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Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in key challenges such as target identification. In the drug…

Biomolecules · Quantitative Biology 2022-06-01 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Charles Tapley Hoyt , William L Hamilton

Knowledge Graph Embeddings (KGE) have become a quite popular class of models specifically devised to deal with ontologies and graph structure data, as they can implicitly encode statistical dependencies between entities and relations in a…

Artificial Intelligence · Computer Science 2023-03-27 Michelangelo Diligenti , Francesco Giannini , Stefano Fioravanti , Caterina Graziani , Moreno Falaschi , Giuseppe Marra

Knowledge graphs (KGs) are a popular way to organise information based on ontologies or schemas and have been used across a variety of scenarios from search to recommendation. Despite advances in KGs, representing knowledge remains a…

Artificial Intelligence · Computer Science 2023-10-10 Christos Theodoropoulos , Natasha Mulligan , Thaddeus Stappenbeck , Joao Bettencourt-Silva

Knowledge Graphs (KGs) and their machine learning counterpart, Knowledge Graph Embedding Models (KGEMs), have seen ever-increasing use in a wide variety of academic and applied settings. In particular, KGEMs are typically applied to KGs to…

Machine Learning · Computer Science 2024-12-16 Jeffrey Sardina , John D. Kelleher , Declan O'Sullivan

Drug discovery and development is a complex and costly process. Machine learning approaches are being investigated to help improve the effectiveness and speed of multiple stages of the drug discovery pipeline. Of these, those that use…

Artificial Intelligence · Computer Science 2022-09-27 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Andreas Bender , Charles Tapley Hoyt , William L Hamilton

Knowledge Graph Embedding (KGE) techniques play a pivotal role in transforming symbolic Knowledge Graphs (KGs) into numerical representations, thereby enhancing various deep learning models for knowledge-augmented applications. Unlike…

Machine Learning · Computer Science 2025-03-24 Guanglin Niu

Knowledge graph embeddings (KGE) apply machine learning methods on knowledge graphs (KGs) to provide non-classical reasoning capabilities based on similarities and analogies. The learned KG embeddings are typically used to answer queries by…

Artificial Intelligence · Computer Science 2025-01-28 Yuqicheng Zhu , Nico Potyka , Jiarong Pan , Bo Xiong , Yunjie He , Evgeny Kharlamov , Steffen Staab

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

Computation and Language · Computer Science 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Knowledge Graph Completion has been increasingly adopted as a useful method for helping address several tasks in biomedical research, such as drug repurposing or drug-target identification. To that end, a variety of datasets and Knowledge…

Machine Learning · Computer Science 2025-11-07 Alberto Cattaneo , Stephen Bonner , Thomas Martynec , Edward Morrissey , Carlo Luschi , Ian P Barrett , Daniel Justus

Knowledge Graphs (KGs) have gained considerable attention recently from both academia and industry. In fact, incorporating graph technology and the copious of various graph datasets have led the research community to build sophisticated…

Artificial Intelligence · Computer Science 2020-06-03 Bilal Abu-Salih , Marwan Al-Tawil , Ibrahim Aljarah , Hossam Faris , Pornpit Wongthongtham

Knowledge graphs (KGs), as structured representations of real world facts, are intelligent databases incorporating human knowledge that can help machine imitate the way of human problem solving. However, KGs are usually huge and there are…

Machine Learning · Computer Science 2023-06-27 Haotian Li , Hongri Liu , Yao Wang , Guodong Xin , Yuliang Wei

Knowledge Graphs (KG) constitute a flexible representation of complex relationships between entities particularly useful for biomedical data. These KG, however, are very sparse with many missing edges (facts) and the visualisation of the…

Artificial Intelligence · Computer Science 2016-12-08 Armando Vieira

A knowledge graph (KG) is a data structure which represents entities and relations as the vertices and edges of a directed graph with edge types. KGs are an important primitive in modern machine learning and artificial intelligence.…

Artificial Intelligence · Computer Science 2021-10-20 Michael R. Douglas , Michael Simkin , Omri Ben-Eliezer , Tianqi Wu , Peter Chin , Trung V. Dang , Andrew Wood

Knowledge Graphs (KGs) are a powerful representation of linked data, offering flexibility, semantic richness, and support for knowledge enrichment and reasoning. They help data owners organize and exploit heterogeneous data to provide…

Cryptography and Security · Computer Science 2026-05-20 Yasmine Hayder

Knowledge Graphs (KGs) have seen increasing use across various domains -- from biomedicine and linguistics to general knowledge modelling. In order to facilitate the analysis of knowledge graphs, Knowledge Graph Embeddings (KGEs) have been…

Machine Learning · Computer Science 2024-12-20 Jeffrey Sardina , John D. Kelleher , Declan O'Sullivan

Knowledge graph (KG) embedding aims at embedding entities and relations in a KG into a lowdimensional latent representation space. Existing KG embedding approaches model entities andrelations in a KG by utilizing real-valued ,…

Machine Learning · Computer Science 2021-03-24 Chengjin Xu , Mojtaba Nayyeri , Yung-Yu Chen , Jens Lehmann

Knowledge graph embedding (KGE) models represent each entity and relation of a knowledge graph (KG) with low-dimensional embedding vectors. These methods have recently been applied to KG link prediction and question answering over…

Computation and Language · Computer Science 2022-03-22 Apoorv Saxena , Adrian Kochsiek , Rainer Gemulla

Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Artificial Intelligence · Computer Science 2023-07-18 Lauren Nicole DeLong , Ramon Fernández Mir , Zonglin Ji , Fiona Niamh Coulter Smith , Jacques D. Fleuriot

Knowledge graph embedding (KGE) models are often used to predict missing links for knowledge graphs (KGs). However, multiple KG embeddings can perform almost equally well for link prediction yet give conflicting predictions for unseen…

Artificial Intelligence · Computer Science 2024-10-07 Yuqicheng Zhu , Nico Potyka , Mojtaba Nayyeri , Bo Xiong , Yunjie He , Evgeny Kharlamov , Steffen Staab

Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has…

Computation and Language · Computer Science 2021-09-22 Rahul Nadkarni , David Wadden , Iz Beltagy , Noah A. Smith , Hannaneh Hajishirzi , Tom Hope
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