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We introduce and analyse an individual-based evolutionary model, in which a population of genetically diverse organisms compete with each other for limited resources. Through theoretical analysis and stochastic simulations, we show that the…

Populations and Evolution · Quantitative Biology 2012-11-02 Tim Rogers , Alan J. McKane , Axel G. Rossberg

Microbiomes are complex systems comprised of many interacting species. Species can survive harsh or changing conditions by rapid adaptation, a process accelerated by the exchange of genetic material between different species through…

Populations and Evolution · Quantitative Biology 2025-09-04 Johannes Nauta , Kaitlin A. Schaal , Ying-Jie Wang , James P. J. Hall , Shai Pilosof , Manlio De Domenico

The foundational concepts behind the persistence of ecological communities have been based on two ecological properties: dynamical stability and feasibility. The former is typically regarded as the capacity of a community to return to an…

Populations and Evolution · Quantitative Biology 2016-01-21 Serguei Saavedra , Rudolf P. Rohr , Jens M. Olesen , Jordi Bascompte

Biological systems must be robust for stable function against perturbations, but robustness alone is not sufficient. The ability to switch between appropriate states (phenotypes) in response to different conditions is essential for…

Populations and Evolution · Quantitative Biology 2023-04-25 Ayaka Sakata , Kunihiko Kaneko

Environmental stochasticity is known to be a destabilizing factor, increasing abundance fluctuations and extinction rates of populations. However, the stability of a community may benefit from the differential response of species to…

Populations and Evolution · Quantitative Biology 2016-02-10 Matan Danino , Nadav M. Shnerb , Sandro Azaele , William E. Kunin , David A. Kessler

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

Populations and Evolution · Quantitative Biology 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

Populations and Evolution · Quantitative Biology 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

What determines biodiversity in nature is a prominent issue in ecology, especially in biotic resource systems that are typically devoid of cross-feeding. Here, we show that by incorporating pairwise encounters among consumer individuals…

Populations and Evolution · Quantitative Biology 2025-06-18 Ju Kang , Shijie Zhang , Yiyuan Niu , Xin Wang

The observation that phenotypic variability is ubiquitous in isogenic populations has led to a multitude of experimental and theoretical studies seeking to probe the causes and consequences of this variability. Whether it be in the context…

Populations and Evolution · Quantitative Biology 2022-02-18 Ethan Levien , Jiseon Min , Jane Kondev , Ariel Amir

Environment plays a fundamental role in the competition for resources, and hence in the evolution of populations. Here, we study a well-mixed, finite population consisting of two strains competing for the limited resources provided by an…

Populations and Evolution · Quantitative Biology 2017-10-16 Karl Wienand , Erwin Frey , Mauro Mobilia

Bacterial chemotaxis systems are as diverse as the environments that bacteria inhabit, but how much environmental variation can cells tolerate with a single system? Diversification of a single chemotaxis system could serve as an…

Populations and Evolution · Quantitative Biology 2015-11-30 Nicholas W Frankel , William Pontius , Yann S Dufour , Junjiajia Long , Luis Hernandez- Nunez , Thierry Emonet

Synergistic and antagonistic interactions in multi-species populations - such as resource sharing and competition - result in remarkably diverse behaviors in populations of interacting cells, such as in soil or human microbiomes, or clonal…

Populations and Evolution · Quantitative Biology 2019-10-15 MattheW Badali , Anton Zilman

Recent theoretical studies have shown that demographic stochasticity can greatly increase the tendency of asexually reproducing phenotypically diverse organisms to spontaneously evolve into localised clusters, suggesting a simple mechanism…

Populations and Evolution · Quantitative Biology 2016-03-23 Luis F. Lafuerza , Alan J. McKane

Cells use genetic switches to shift between alternate gene expression states, e.g., to adapt to new environments or to follow a developmental pathway. Here, we study the dynamics of switching in a generic-feedback on/off switch. Unlike…

Molecular Networks · Quantitative Biology 2015-05-27 Michael Assaf , Elijah Roberts , Zaida Luthey-Schulten

Non-genetic perturbations, such as environmental change or developmental noise, can induce novel phenotypes. If an induced phenotype confers a fitness advantage, selection may promote its genetic stabilization. Non-genetic perturbations can…

Populations and Evolution · Quantitative Biology 2015-03-17 Carlos Espinosa-Soto , Olivier C. Martin , Andreas Wagner

Individuals within any species exhibit differences in size, developmental state, or spatial location. These differences coupled with environmental fluctuations in demographic rates can have subtle effects on population persistence and…

Populations and Evolution · Quantitative Biology 2015-12-16 Gregory Roth , Sebastian J. Schreiber

Molecular phenotypes are important links between genomic information and organismic functions, fitness, and evolution. Complex phenotypes, which are also called quantitative traits, often depend on multiple genomic loci. Their evolution…

Populations and Evolution · Quantitative Biology 2015-06-12 Armita Nourmohammad , Stephan Schiffels , Michael Laessig

Structure, composition and stability of ecological populations are shaped by the inter- and intra-species interactions within these communities. It remains to be fully understood how the interplay of these interactions with other factors,…

Populations and Evolution · Quantitative Biology 2023-01-16 Nava Leibovich , Jeremy Rothschild , Sidhartha Goyal , Anton Zilman

Interactions in natural communities can be highly heterogeneous, with any given species interacting appreciably with only some of the others, a situation commonly represented by sparse interaction networks. We study the consequences of…

Populations and Evolution · Quantitative Biology 2022-10-12 Stav Marcus , Ari M. Turner , Guy Bunin

In complex ecosystems such as microbial communities, there is constant ecological and evolutionary feedback between the residing species and the environment occurring on concurrent timescales. Species respond and adapt to their surroundings…

Populations and Evolution · Quantitative Biology 2023-10-17 Jim Wu , David J. Schwab , Trevor GrandPre