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We introduce Deep Linear Discriminant Analysis (DeepLDA) which learns linearly separable latent representations in an end-to-end fashion. Classic LDA extracts features which preserve class separability and is used for dimensionality…

Machine Learning · Computer Science 2016-02-18 Matthias Dorfer , Rainer Kelz , Gerhard Widmer

The task of predicting long-term patient outcomes using supervised machine learning is a challenging one, in part because of the high variance of each patient's trajectory, which can result in the model over-fitting to the training data.…

Machine Learning · Computer Science 2026-02-09 Thomas Frost , Kezhi Li , Steve Harris

An individualized treatment rule (ITR) is a decision rule that aims to improve individual patients health outcomes by recommending optimal treatments according to patients specific information. In observational studies, collected data may…

Methodology · Statistics 2023-10-03 Zeyu Bian , Erica EM Moodie , Susan M Shortreed , Sylvie D Lambert , Sahir Bhatnagar

Recently many first and second order variants of SGD have been proposed to facilitate training of Deep Neural Networks (DNNs). A common limitation of these works stem from the fact that they use the same learning rate across all instances…

Machine Learning · Computer Science 2021-05-31 Shreyas Saxena , Nidhi Vyas , Dennis DeCoste

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

Classification tasks require a balanced distribution of data to ensure the learner to be trained to generalize over all classes. In real-world datasets, however, the number of instances vary substantially among classes. This typically leads…

Machine Learning · Computer Science 2020-11-24 Joel Jang , Yoonjeon Kim , Kyoungho Choi , Sungho Suh

Precision medicine involves developing individualized treatment regimes (ITRs) which allow for treatment decisions to be tailored to patient characteristics. Naturally, the identification of the optimal regime, that is, the rule which…

Methodology · Statistics 2025-09-30 Misha Dolmatov , Erica E. M. Moodie , David A. Stephens , Dipankar Bandyopadhyay

Machine learning algorithms with empirical risk minimization are vulnerable under distributional shifts due to the greedy adoption of all the correlations found in training data. There is an emerging literature on tackling this problem by…

Machine Learning · Computer Science 2022-11-22 Jiashuo Liu , Zheyan Shen , Peng Cui , Linjun Zhou , Kun Kuang , Bo Li

Multi-task learning (MTL) has emerged as a successful strategy in industrial-scale recommender systems, offering significant advantages such as capturing diverse users' interests and accurately detecting different behaviors like ``click" or…

Machine Learning · Computer Science 2025-10-14 Yuguang Liu , Yiyun Miao , Luyao Xia

Conventional treatment policies map patient covariates to a single recommended intervention in order to maximize expected clinical outcomes. Although a rich body of causal inference methods has been developed to estimate such policies,…

Machine Learning · Computer Science 2026-05-20 Laura Fuentes-Vicente , Mathieu Even , Gaëlle Dormion , Antoine Chambaz , Uri Shalit , Julie Josse

Integrative analysis of multiple datasets for estimating optimal individualized treatment rules (ITRs) can enhance decision efficiency. A central challenge is posterior shift, wherein the conditional distribution of potential outcomes given…

Machine Learning · Statistics 2026-03-09 Wenhai Cui , Wen Su , Xingqiu Zhao

Self-distillation (SD) offers a promising path for adapting large language models (LLMs) without relying on stronger external teachers. However, SD in autoregressive LLMs remains challenging because self-generated trajectories are…

Computation and Language · Computer Science 2026-05-22 Yiqiao Jin , Yiyang Wang , Lucheng Fu , Yijia Xiao , Yinyi Luo , Haoxin Liu , B. Aditya Prakash , Josiah Hester , Jindong Wang , Srijan Kumar

Researchers and practitioners are increasingly considering reinforcement learning to optimize decisions in complex domains like robotics and healthcare. To date, these efforts have largely utilized expectation-based learning. However,…

Machine Learning · Computer Science 2026-04-13 Zequn Chen , Wesley J. Marrero

Low precision weights, activations, and gradients have been proposed as a way to improve the computational efficiency and memory footprint of deep neural networks. Recently, low precision networks have even shown to be more robust to…

Machine Learning · Computer Science 2018-07-04 Griffin Lacey , Graham W. Taylor , Shawki Areibi

Machine learning algorithms with empirical risk minimization are vulnerable under distributional shifts due to the greedy adoption of all the correlations found in training data. Recently, there are robust learning methods aiming at this…

Machine Learning · Computer Science 2021-05-12 Jiashuo Liu , Zheyan Shen , Peng Cui , Linjun Zhou , Kun Kuang , Bo Li , Yishi Lin

Dynamic Treatment Regimes (DTRs) provide a systematic approach for making sequential treatment decisions that adapt to individual patient characteristics, particularly in clinical contexts where survival outcomes are of interest.…

Machine Learning · Computer Science 2025-03-11 Animesh Kumar Paul , Russell Greiner

Arguably the biggest challenge in applying neural networks is tuning the hyperparameters, in particular the learning rate. The sensitivity to the learning rate is due to the reliance on backpropagation to train the network. In this paper we…

Machine Learning · Statistics 2018-08-08 Francois Fagan , Garud Iyengar

Ensembling a neural network is a widely recognized approach to enhance model performance, estimate uncertainty, and improve robustness in deep supervised learning. However, deep ensembles often come with high computational costs and memory…

Error backpropagation is a highly effective mechanism for learning high-quality hierarchical features in deep networks. Updating the features or weights in one layer, however, requires waiting for the propagation of error signals from…

Neural and Evolutionary Computing · Computer Science 2017-11-21 Hesham Mostafa , Vishwajith Ramesh , Gert Cauwenberghs

Distributed Deep Learning (DDL) is essential for large-scale Deep Learning (DL) training. Synchronous Stochastic Gradient Descent (SSGD) 1 is the de facto DDL optimization method. Using a sufficiently large batch size is critical to…

Machine Learning · Computer Science 2021-12-03 Wei Zhang , Mingrui Liu , Yu Feng , Xiaodong Cui , Brian Kingsbury , Yuhai Tu