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Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Designing efficient quantum circuits is a central bottleneck to exploring the potential of quantum computing, particularly for noisy intermediate-scale quantum (NISQ) devices, where circuit efficiency and resilience to errors are paramount.…

Quantum Physics · Physics 2025-10-31 Jun Dai , Michael Rizvi-Martel , Guillaume Rabusseau

DNA pattern matching is essential for many widely used bioinformatics applications. Disease diagnosis is one of these applications, since analyzing changes in DNA sequences can increase our understanding of possible genetic diseases. The…

Hardware Architecture · Computer Science 2022-06-01 Jinane Bazzi , Jana Sweidan , Mohammed E. Fouda , Rouwaida Kanj , Ahmed M. Eltawil

This briefing paper focuses on data equity within foundation models, both in terms of the impact of Generative AI (genAI) on society and on the further development of genAI tools. GenAI promises immense potential to drive digital and social…

The rapid advancement of DNA sequencing has produced vast genomic datasets, yet interpreting and engineering genomic function remain fundamental challenges. Recent large language models have opened new avenues for genomic analysis, but…

In this paper, we propose the Neural Knowledge DNA, a framework that tailors the ideas underlying the success of neural networks to the scope of knowledge representation. Knowledge representation is a fundamental field that dedicate to…

Artificial Intelligence · Computer Science 2016-03-01 Haoxi Zhang , Cesar Sanin , Edward Szczerbicki

Designers rely on visual search to explore and develop ideas in early design stages. However, designers can struggle to identify suitable text queries to initiate a search or to discover images for similarity-based search that can…

Human-Computer Interaction · Computer Science 2024-03-05 Kihoon Son , DaEun Choi , Tae Soo Kim , Young-Ho Kim , Juho Kim

Generative AI is reshaping how computing systems are designed, optimized, and built, yet research remains fragmented across software, architecture, and chip design communities. This paper takes a cross-stack perspective, examining how…

Most state-of-the-art Graph Neural Networks (GNNs) can be defined as a form of graph convolution which can be realized by message passing between direct neighbors or beyond. To scale such GNNs to large graphs, various neighbor-, layer-, or…

Machine Learning · Computer Science 2021-10-28 Mucong Ding , Kezhi Kong , Jingling Li , Chen Zhu , John P Dickerson , Furong Huang , Tom Goldstein

The rapid development of the DNA nanotechnology field has been facilitated by advances in CAD software. However, as more complex concepts arose, the lag between the needs and software capabilities appeared. Further derailed by manual…

Quantitative Methods · Quantitative Biology 2021-11-30 Samson Petrosyan , Grigory Tikhomirov

Exploiting the properties of quantum information to the benefit of machine learning models is perhaps the most active field of research in quantum computation. This interest has supported the development of a multitude of software…

Quantum Physics · Physics 2023-10-24 Francesco Di Marcantonio , Massimiliano Incudini , Davide Tezza , Michele Grossi

Spanning two decades, the Encyclopaedia of DNA Elements (ENCODE) is a collaborative research project that aims to identify all the functional elements in the human and mouse genomes. To best serve the scientific community, all data…

The availability of rich 3D datasets corresponding to the geometrical complexity of the built environments is considered an ongoing challenge for 3D deep learning methodologies. To address this challenge, we introduce GenScan, a generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Mohammad Keshavarzi , Oladapo Afolabi , Luisa Caldas , Allen Y. Yang , Avideh Zakhor

Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

Machine Learning · Statistics 2023-04-11 Alan Nawzad Amin , Eli Nathan Weinstein , Debora Susan Marks

Generative art unlocks boundless creative possibilities, yet its full potential remains untapped due to the technical expertise required for advanced architectural concepts and computational workflows. To bridge this gap, we present…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Duc-Hung Nguyen , Huu-Phuc Huynh , Minh-Triet Tran , Trung-Nghia Le

We propose a novel and flexible DNA-storage architecture, which divides the storage space into fixed-size units (blocks) that can be independently and efficiently accessed at random for both read and write operations, and further allows…

Emerging Technologies · Computer Science 2023-10-02 Puru Sharma , Cheng-Kai Lim , Dehui Lin , Yash Pote , Djordje Jevdjic

DNA-coated colloids can crystallize into a multitude of lattices, ranging from face-centered cubic to diamond and thereby contribute to our understanding of crystallization and open avenues to producing structures with useful photonic…

Soft Condensed Matter · Physics 2026-04-17 Pepijn G. Moerman , Huang Fang , Thomas E. Videbæk , W. Benjamin Rogers , Rebecca Schulman

Superconducting quantum hardware architectures have been designed by considering the physical constraints of the underlying physics. These general-purpose architectures leave room for customization and optimization that can be exploited…

Quantum Physics · Physics 2024-05-06 Jagatheesan Kunasaikaran , Kevin Mato , Robert Wille

LAGE is a systematic framework developed in Java. The motivation of LAGE is to provide a scalable and parallel solution to reconstruct Gene Regulatory Networks (GRNs) from continuous gene expression data for very large amount of genes. The…

Machine Learning · Computer Science 2012-11-12 Yang Lu , Mengying Wang , Kenny Q. Zhu , Bo Yuan

Quantum circuits that generate coherent superpositions of stochastic processes are key to many downstream quantum-accelerated tasks, such as risk analysis, importance sampling, and DNA sequencing. However, traditional methods for designing…

Quantum Physics · Physics 2026-03-26 Ximing Wang , Chengran Yang , Chidambaram Aditya Somasundaram , Jayne Thompson , Mile Gu