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The presence of a large number of infected individuals with few or no symptoms is an important epidemiological difficulty and the main mathematical feature of COVID-19. The A-SIR model, i.e. a SIR (Susceptible-Infected-Removed) model with a…

Populations and Evolution · Quantitative Biology 2020-08-19 Armando G. M. Neves , Gustavo Guerrero

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

Populations and Evolution · Quantitative Biology 2020-05-04 Andrew Lesniewski

We propose a robust parameter estimation method for dynamical systems based on Statistical Learning techniques which aims to estimate a set of parameters that well fit the dynamics in order to obtain robust evidences about the qualitative…

Methodology · Statistics 2021-02-26 Diego Marcondes

In this paper we develop a nonparametric maximum likelihood estimate of the mixing distribution of the parameters of a linear stochastic dynamical system. This includes, for example, pharmacokinetic population models with process and…

Methodology · Statistics 2015-09-16 Alona Kryshchenko , Alan Schumitzky , Mike van Guilder , Michael Neely

COVID-19, due to its accelerated spread has brought in the need to use assistive tools for faster diagnosis in addition to typical lab swab testing. Chest X-Rays for COVID cases tend to show changes in the lungs such as ground glass…

Image and Video Processing · Electrical Eng. & Systems 2020-10-27 Gayathiri Murugamoorthy , Naimul Khan

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

Computation · Statistics 2022-11-02 Georgios Efstathiadis

The U.S. Covid-19 data exhibit a high-frequency oscillation along a low-frequency wave for outbreaks. There is no model to account for it. A modified SIR model is proposed to explain this spiking phenomenon. It is also used to best-fit the…

Populations and Evolution · Quantitative Biology 2023-11-21 Bo Deng

Accurate forecasts of COVID-19 is central to resource management and building strategies to deal with the epidemic. We propose a heterogeneous infection rate model with human mobility for epidemic modeling, a preliminary version of which we…

Populations and Evolution · Quantitative Biology 2020-05-06 Ajitesh Srivastava , Viktor K. Prasanna

Current efforts of modelling COVID-19 are often based on the standard compartmental models such as SEIR and their variations. As pre-symptomatic and asymptomatic cases can spread the disease between populations through travel, it is…

Physics and Society · Physics 2020-10-06 Xiaoye Ding , Shenyang Huang , Abby Leung , Reihaneh Rabbany

We demonstrate the ability of statistical data assimilation to identify the measurements required for accurate state and parameter estimation in an epidemiological model for the novel coronavirus disease COVID-19. Our context is an effort…

Populations and Evolution · Quantitative Biology 2020-08-04 Eve Armstrong , Manuela Runge , Jaline Gerardin

We present a numerical implementation for a multilayer network used to model the transmission of Covid-19 or other diseases with a similar transmission mechanism. The model incorporates different contact types between individuals…

Physics and Society · Physics 2021-03-17 Juan G. Calvo , Fabio Sanchez , Luis A. Barboza , Yury E. García , Paola Vásquez

In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

Populations and Evolution · Quantitative Biology 2020-05-22 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

Effective epidemic modeling and surveillance require computationally efficient methods that can continuously update estimates as new data becomes available. This paper explores the application of an online variant of Sequential Monte Carlo…

Populations and Evolution · Quantitative Biology 2025-09-09 Dhorasso Temfack , Jason Wyse

We adopt a maximum-likelihood framework to estimate parameters of a stochastic susceptible-infected-recovered (SIR) model with contact tracing on a rooted random tree. Given the number of detectees per index case, our estimator allows to…

Dynamical Systems · Mathematics 2023-11-23 Augustine Okolie , Johannes Müller , Mirjam Kretzschmar

The aim of the paper is to describe two models of Covid-19 infection dynamics. For this purpose a special class of branching processes with two types of individuals is considered. These models are intended to use only the observed daily…

Populations and Evolution · Quantitative Biology 2020-05-05 Nikolay M. Yanev , Vessela K. Stoimenova , Dimitar V. Atanasov

In a world being hit by waves of COVID-19, vaccination is a light on the horizon. However, the roll-out of vaccination strategies and their influence on the pandemic are still open problems. In order to compare the effect of various…

Physics and Society · Physics 2021-04-23 N. L. Barreiro , C. I. Ventura , T. Govezensky , M. Núñez , P. G. Bolcatto , R. A. Barrio

A novel yet simple extension of the symmetric logistic distribution is proposed by introducing a skewness parameter. It is shown how the three parameters of the ensuing skew logistic distribution may be estimated using maximum likelihood.…

Physics and Society · Physics 2022-05-06 Mark Levene

With the prevalence of COVID-19, the modeling of epidemic propagation and its analyses have played a significant role in controlling epidemics. However, individual behaviors, in particular the self-protection and migration, which have a…

Social and Information Networks · Computer Science 2025-11-25 Yuhan Li , Ziyan Zeng , Minyu Feng , Jürgen Kurths

As the COVID-19 pandemic continues to ravage the world, it is of critical significance to provide a timely risk prediction of the COVID-19 in multi-level. To implement it and evaluate the public health policies, we develop a framework with…

Physics and Society · Physics 2020-12-02 Lingxiao Wang , Tian Xu , Till Hannes Stoecker , Horst Stoecker , Yin Jiang , Kai Zhou

Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…

Computation · Statistics 2017-02-14 Jonathan Fintzi , Xiang Cui , Jon Wakefield , Vladimir N. Minin