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The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

The need to forecast COVID-19 related variables continues to be pressing as the epidemic unfolds. Different efforts have been made, with compartmental models in epidemiology and statistical models such as AutoRegressive Integrated Moving…

Applications · Statistics 2020-10-07 Bahman Rostami-Tabar , Juan F. Rendon-Sanchez

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

Objective: COVID-19 has spread worldwide and made a huge influence across the world. Modeling the infectious spread situation of COVID-19 is essential to understand the current condition and to formulate intervention measurements.…

Machine Learning · Computer Science 2023-06-23 Ruhan Liu , Jiajia Li , Yang Wen , Huating Li , Ping Zhang , Bin Sheng , David Dagan Feng

In this paper we model the spreading of the SARS-CoV-2 in Mexico by introducing a new stochastic approximation constructed from first principles, structured on the basis of a Latent-Infectious- (Recovered or Deceased) (LI(RD)) compartmental…

Populations and Evolution · Quantitative Biology 2023-01-11 Pablo Carlos López Vázquez , Gilberto Sánchez González , Jorge Martínez Ortega , Renato Salomón Arroyo Duarte

In this paper we develop a SIR epidemiological model with parameters calculated according to existing data at the time of writing (24/03/2020); the data is from Italy, South Korea and Colombia, the model is then used to project the…

Populations and Evolution · Quantitative Biology 2020-09-28 Carlos Armando De Castro

The coronavirus disease 2019 (COVID-19) pandemic radically impacts our lives, while the transmission/infection and recovery dynamics of COVID-19 remain obscure. A time-dependent Susceptible, Exposed, Infectious, and Recovered (SEIR) model…

Populations and Evolution · Quantitative Biology 2020-04-01 Yong Zhang , Xiangnan Yu , HongGuang Sun , Geoffrey R. Tick , Wei Wei , Bin Jin

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Optimization and Control · Mathematics 2020-08-20 Mauricio C. de Oliveira

Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with…

Populations and Evolution · Quantitative Biology 2022-01-31 Jason Hindes , Michael Assaf , Ira B. Schwartz

In this work, we adapt the epidemiological SIR model to study the evolution of the dissemination of COVID-19 in Germany and Brazil (nationally, in the State of Paraiba, and in the City of Campina Grande). We prove the well posedness and the…

Populations and Evolution · Quantitative Biology 2022-04-20 Adriano A. Batista , Severino Horácio da Silva

In this work we evaluate the applicability of an ensemble of population models and machine learning models to predict the near future evolution of the COVID-19 pandemic, with a particular use case in Spain. We rely solely in open and public…

We study maximum likelihood estimation in log-linear models under conditional Poisson sampling schemes. We derive necessary and sufficient conditions for existence of the maximum likelihood estimator (MLE) of the model parameters and…

Statistics Theory · Mathematics 2012-07-24 Stephen E. Fienberg , Alessandro Rinaldo

Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardless of the employed fatality measure, the infected population…

Quantitative Methods · Quantitative Biology 2021-12-28 Lucas Böttcher , Maria D'Orsogna , Tom Chou

We propose a novel approach that integrates machine learning into compartmental disease modeling to predict the progression of COVID-19. Our model is explainable by design as it explicitly shows how different compartments evolve and it uses…

This paper considers maximum likelihood (ML) estimation in a large class of models with hidden Markov regimes. We investigate consistency of the ML estimator and local asymptotic normality for the models under general conditions which allow…

Statistics Theory · Mathematics 2021-12-07 Demian Pouzo , Zacharias Psaradakis , Martin Sola

In the absence of other tools, monitoring the effects of protective measures, including social distancing and forecasting the outcome of outbreaks is of immense interest. Real-time data is noisy and very often hampered by systematic errors…

Populations and Evolution · Quantitative Biology 2020-08-11 Gabor Vattay

During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage…

Machine Learning · Computer Science 2021-01-05 Cornelius Fritz , Emilio Dorigatti , David Rügamer

Objective. The COVID-19 pandemic has threatened to collapse hospital and ICU services, and it has affected the care programs for non-COVID patients. The objective was to develop a mathematical model designed to optimize predictions related…

COVID-19 has been a public health emergency of international concern since early 2020. Reliable forecasting is critical to diminish the impact of this disease. To date, a large number of different forecasting models have been proposed,…

Machine Learning · Computer Science 2021-10-04 Yun Zhao , Yuqing Wang , Junfeng Liu , Haotian Xia , Zhenni Xu , Qinghang Hong , Zhiyang Zhou , Linda Petzold

In this study, we have formulated and analyzed a non-linear compartmental model (SEIR) for the dynamics of COVID-19 with reference to immigration from urban to rural population in Indian scenario. We have captured the effect of the…

Dynamical Systems · Mathematics 2022-05-12 D. K. K. Vamsi , C. Bishal Chhetri , D. Bhanu Prakash , Seshasainath Ch. , D. Surabhi Pandey
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