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Nanoscale biosystems are widely used in numerous medical applications. The approaches for structure and function of the nanomachines that are available in the cell (natural nanomachines) are discussed. Molecular simulation studies have been…

Biological Physics · Physics 2016-09-08 Babu A Manjasetty , T. R. Gopalakrishnan Nair , Y. S. Ramaswamy

Registration is an essential tool in image analysis. Deep learning based alternatives have recently become popular, achieving competitive performance at a faster speed. However, many contemporary techniques are limited to volumetric…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Balder Croquet , Daan Christiaens , Seth M. Weinberg , Michael Bronstein , Dirk Vandermeulen , Peter Claes

Neural Architecture Search (NAS) algorithms are intended to remove the burden of manual neural network design, and have shown to be capable of designing excellent models for a variety of well-known problems. However, these algorithms…

Machine Learning · Computer Science 2022-04-21 Rob Geada , Andrew Stephen McGough

Our work is concerned with the generation and targeted design of RNA, a type of genetic macromolecule that can adopt complex structures which influence their cellular activities and functions. The design of large scale and complex…

Biomolecules · Quantitative Biology 2021-02-02 Zichao Yan , William L. Hamilton , Mathieu Blanchette

Latent diffusion models such as Stable Diffusion 1.5 offer strong generative priors that are highly valuable for image restoration, yet their full pipelines remain too computationally heavy for deployment on edge devices. Existing…

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single- and few-atom thick layers of 2D materials beyond graphene, and also that these materials can exhibit fascinating and…

Mesoscale and Nanoscale Physics · Physics 2022-01-19 Benjamin O. Tayo

The democratization of fabrication equipment has spurred recent interest in maskless grayscale lithography for both 2D and 3D microfabrication. However, the design of suitable template images remains a challenge. This work presents a…

While the keypoint-based maps created by sparse monocular simultaneous localisation and mapping (SLAM) systems are useful for camera tracking, dense 3D reconstructions may be desired for many robotic tasks. Solutions involving depth cameras…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Tristan Laidlow , Jan Czarnowski , Stefan Leutenegger

The Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked 2.5 kb-long DNA minicircles found in certain parasites called Trypanosomes. Understanding the self-assembly and replication of this structure are…

Soft Condensed Matter · Physics 2022-09-07 Pinyao He , Allard J. Katan , Luca Tubiana , Cees Dekker , Davide Michieletto

We present Brownian dynamics simulations of the facilitated diffusion of a protein, modelled as a sphere with a binding site on its surface, along DNA, modelled as a semi-flexible polymer. We consider both the effect of DNA organisation in…

Biological Physics · Physics 2012-12-10 C. A. Brackley , M. E. Cates , D. Marenduzzo

A construction method for duplex cage structures with icosahedral sym- metry made out of single-stranded DNA molecules is presented and applied to an icosidodecahedral cage. It is shown via a mixture of analytic and computer techniques that…

Biomolecules · Quantitative Biology 2013-04-09 N. E. Grayson , A. Taormina , R. Twarock

X-ray computed tomography at the nanometer scale (nano-CT) offers a wide range of applications in scientific and industrial areas. Here we describe a reliable, user-friendly and fast software package based on LabVIEW that may allow to…

Computational Engineering, Finance, and Science · Computer Science 2015-01-13 Shenghao Wang , Kai Zhang , Zhili Wang , Kun Gao , Zhao Wu , Peiping Zhu , Ziyu Wu

Drug discovery is a complex, resource-intensive process requiring significant time and cost to bring new medicines to patients. Many generative models aim to accelerate drug discovery, but few produce synthetically accessible molecules.…

Machine Learning · Computer Science 2025-01-30 Zygimantas Jocys , Zhanxing Zhu , Henriette M. G. Willems , Katayoun Farrahi

As the global need for large-scale data storage is rising exponentially, existing storage technologies are approaching their theoretical and functional limits in terms of density and energy consumption, making DNA based storage a potential…

Emerging Technologies · Computer Science 2021-10-12 Yotam Nahum , Eyar Ben-Tolila , Leon Anavy

Traditional sheet metal forming relies on time-consuming and expensive Finite Element Analysis (FEA) for design validation, a process that significantly prolongs design cycles. While surrogate models offer faster iteration, current…

Machine Learning · Computer Science 2026-05-20 Jiajie Luo , Mohamed Mohamed , Osama Hassan , Haosu Zhou , Yingxue Zhao , Haoran Li , Xinrun Li , Zhutao Shao , Yang Long , Nan Li , Jichun Li

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

Creating flexible 3D scenes from a single image is vital when direct 3D data acquisition is costly or impractical. We introduce NavCrafter, a novel framework that explores 3D scenes from a single image by synthesizing novel-view video…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Hongbo Duan , Peiyu Zhuang , Yi Liu , Zhengyang Zhang , Yuxin Zhang , Pengting Luo , Fangming Liu , Xueqian Wang

Despite many studies on how geometry can be used to control the electronic properties of graphene, certain limitations to fabrication of designed graphene nanostructures exist. Here, we demonstrate controlled topographical replication of…

Mesoscale and Nanoscale Physics · Physics 2015-06-19 Y. Moon , J. Shin , S. Seo , J. Park , S. R. Dugasani , S. H. Woo , T. Park , S. H. Park , J. R. Ahn

Neural Architecture Search (NAS) is a popular tool for automatically generating Neural Network (NN) architectures. In early NAS works, these tools typically optimized NN architectures for a single metric, such as accuracy. However, in the…

Neural and Evolutionary Computing · Computer Science 2023-04-05 Emil Njor , Jan Madsen , Xenofon Fafoutis

Fabrication of DNA nanostructures primarily follows two fundamental rules. First, DNA oligonucleotides mutually combine by Watson-Crick base pairing rules between complementary base sequences. Second, the geometrical compatibility of the…

Mesoscale and Nanoscale Physics · Physics 2011-06-01 Jihoon Shin , Junghoon Kim , Rashid Amin , Seungjae Kim , Young Hun Kwon , Sung Ha Park