English
Related papers

Related papers: Sensitivity analysis in an Immuno-Epidemiological …

200 papers

In the presence of treatment effect heterogeneity, the average treatment effect (ATE) in a randomized controlled trial (RCT) may differ from the average effect of the same treatment if applied to a target population of interest. If all…

Methodology · Statistics 2017-05-02 Trang Quynh Nguyen , Cyrus Ebnesajjad , Stephen R. Cole , Elizabeth A. Stuart

Understanding the dynamics of infectious disease spread in a heterogeneous population is an important factor in designing control strategies. Here, we develop a novel tensor-driven multi-compartment version of the classic…

Populations and Evolution · Quantitative Biology 2020-04-22 Inbar Seroussi , Nir Levy , Elad Yom-Tov

The scope of this work is to serve as a guiding tool against subjective estimations on real pandemic situations (mainly due to the inability to acquire objective real data over whole populations). The previously introduced model of closed…

Physics and Society · Physics 2020-05-18 Y. Contoyiannis , S. G. Stavrinides , M. P. Hanias , M. Kampitakis , P. Papadopoulos , S. Potirakis

This paper investigates the spread of infectious diseases within a networked community by integrating epidemic transmission and public opinion dynamics. We propose a novel discrete-time networked SIS (Susceptible-Infectious-Susceptible)…

Systems and Control · Electrical Eng. & Systems 2025-08-14 Qiulin Xu , Tatsuya Masada , Hideaki Ishii

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

Physics and Society · Physics 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

Covid-19 is one of the most dreaded pandemics/epidemics in the world threatening the human population. The dynamics of this pandemic is quite complicated and prediction of pandemic states often fails. In this work, we study and correlate…

Populations and Evolution · Quantitative Biology 2021-10-06 Jyoti Bhadana , R. K. Brojen Singh

We present a new method for analyzing stochastic epidemic models under minimal assumptions. The method, dubbed DSA, is based on a simple yet powerful observation, namely that population-level mean-field trajectories described by a system of…

Populations and Evolution · Quantitative Biology 2022-02-22 Francesco Di Lauro , Wasiur R. KhudaBukhsh , Istvan Z. Kiss , Eben Kenah , Max Jensen , Grzegorz A. Rempala

We propose a network behavioral-feedback Susceptible-Infected-Recovered (SIR) epidemic model in which the interaction matrix describing the infection rates across subpopulations depends in feedback on the current epidemic state. This model…

Dynamical Systems · Mathematics 2025-07-08 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani

The surprisingly mercurial Covid-19 pandemic has highlighted the need to not only accelerate research on infectious disease, but to also study them using novel techniques and perspectives. A major contributor to the difficulty of containing…

Populations and Evolution · Quantitative Biology 2022-07-21 Aminur Rahman , Angela Peace , Ramesh Kesawan , Souparno Ghosh

Research in epidemiology often focusses on designing interventions that result in the number of infected individuals asymptotically approaching zero, without considering that this number may peak at high values during transients. Recent…

Optimization and Control · Mathematics 2020-03-24 Willem Esterhuizen , Tim Aschenbruck , Jean Lévine , Stefan Streif

Sensitivity analysis is widely used to assess the robustness of causal conclusions in observational studies, yet its interaction with the structure of measured covariates is often overlooked. When latent confounders cannot be directly…

Methodology · Statistics 2026-02-17 Abhinandan Dalal , Iris Horng , Yang Feng , Dylan S. Small

Despite the advanced stage of epidemic modeling, there is a major demand for methods to incorporate behavioral responses to the spread of a disease such as social distancing and adoption of prevention methods. Mobility plays an important…

Physics and Society · Physics 2022-03-14 Paulo Cesar Ventura , Alberto Aleta , Francisco A. Rodrigues , Yamir Moreno

The Susceptible-Infected-Recovered (SIR) model has successfully mimicked the propagation of such airborne diseases as influenza A (H1N1). Although the SIR model has recently been studied in a multilayer networks configuration, in almost all…

Physics and Society · Physics 2015-07-16 L. G. Alvarez Zuzek , H. E. Stanley , L. A. Braunstein

We study the influence of global, local and community-level risk perception on the extinction probability of a disease in several models of social networks. In particular, we study the infection progression as a…

Physics and Society · Physics 2012-12-05 Franco Bagnoli , Daniel Borkmann , Andrea Guazzini , Emanuele Massaro , Stefan Rudolph

For many infectious diseases, a small-world network on an underlying regular lattice is a suitable simplified model for the contact structure of the host population. It is well known that the contact network, described in this setting by a…

Populations and Evolution · Quantitative Biology 2009-11-11 M. M. Telo da Gama , A. Nunes

A model based on a thermodynamic approach is proposed for predicting the dynamics of communicable epidemics in a city, when the epidemic is governed by controlling efforts of multiple scales so that an entropy is associated with the system.…

Medical Physics · Physics 2013-10-01 W. B. Wang , Z. N. Wu , Z. M. Cao , R. F. Hu

In this paper, we explore whether the infection-rate of a disease can serve as a robust monitoring variable in epidemiological surveillance algorithms. The infection-rate is dependent on population mixing patterns that do not vary…

Applications · Statistics 2024-07-17 Wyatt Bridgman , Cosmin Safta , Jaideep Ray

Many models in mathematical epidemiology are developed with the aim to provide a framework for parameter estimation and then prediction. It is well-known that parameters are not always uniquely identifiable. In this paper we consider…

Dynamical Systems · Mathematics 2022-08-17 István Zoltán Kiss , Péter L. Simon

Epidemic models play a key role in understanding and responding to the emerging COVID-19 pandemic. Widely used compartmental models are static and are of limited use to evaluate intervention strategies with the emerging pandemic. Applying…

Populations and Evolution · Quantitative Biology 2021-01-01 Shuo Wang , Xian Yang , Ling Li , Philip Nadler , Rossella Arcucci , Yuan Huang , Zhongzhao Teng , Yike Guo

Disease classification is a crucial element of biomedical research. Recent studies have demonstrated that machine learning techniques, such as Support Vector Machine (SVM) modeling, produce similar or improved predictive capabilities in…

Machine Learning · Statistics 2017-08-02 Jessica M. Rudd