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We consider the problem of controlling an invasive mechanical ventilator for pressure-controlled ventilation: a controller must let air in and out of a sedated patient's lungs according to a trajectory of airway pressures specified by a…

The management of invasive mechanical ventilation, and the regulation of sedation and analgesia during ventilation, constitutes a major part of the care of patients admitted to intensive care units. Both prolonged dependence on mechanical…

Artificial Intelligence · Computer Science 2017-04-24 Niranjani Prasad , Li-Fang Cheng , Corey Chivers , Michael Draugelis , Barbara E Engelhardt

Mechanical ventilation is a critical life support intervention that delivers controlled air and oxygen to a patient's lungs, assisting or replacing spontaneous breathing. While several data-driven approaches have been proposed to optimize…

Machine Learning · Computer Science 2025-01-10 Joo Seung Lee , Malini Mahendra , Anil Aswani

Deciding on appropriate mechanical ventilator management strategies significantly impacts the health outcomes for patients with respiratory diseases. Acute Respiratory Distress Syndrome (ARDS) is one such disease that requires careful…

Systems and Control · Electrical Eng. & Systems 2024-11-13 Isaac Ronald Ward , Dylan M. Asmar , Mansur Arief , Jana Krystofova Mike , Mykel J. Kochenderfer

Mechanical ventilators sustain life of patients that are unable to breathe (sufficiently) on their own. The aim of this paper is to improve pressure tracking performance of mechanical ventilators for a wide variety of sedated patients. This…

Systems and Control · Electrical Eng. & Systems 2020-04-02 Joey Reinders , Ruben Verkade , Bram Hunnekens , Nathan van de Wouw , Tom Oomen

In addition to its public health crisis, COVID-19 pandemic has led to the shutdown and closure of workplaces with an estimated total cost of more than $16 trillion. Given the long hours an average person spends in buildings and indoor…

Systems and Control · Electrical Eng. & Systems 2022-12-29 Ashkan Haji Hosseinloo , Saleh Nabi , Anette Hosoi , Munther A. Dahleh

Clinical decision support systems (CDSS) will play an in-creasing role in improving the quality of medical care for critically ill patients. However, due to limitations in current informatics infrastructure, CDSS do not always have…

Machine Learning · Computer Science 2019-05-01 Gregory B. Rehm , Brooks T. Kuhn , Jimmy Nguyen , Nicholas R. Anderson , Chen-Nee Chuah , Jason Y. Adams

This paper presents a recurrent neural network approach to simulating mechanical ventilator pressure. The traditional mechanical ventilator has a control pressure that is monitored by a medical practitioner and can behave incorrectly if the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-10 Su Diao , Changsong Wei , Junyu Wang , Yizhou Li

Mechanical ventilation is a key form of life support for patients with pulmonary impairment. Healthcare workers are required to continuously adjust ventilator settings for each patient, a challenging and time consuming task. Hence, it would…

Machine Learning · Computer Science 2022-10-07 Flemming Kondrup , Thomas Jiralerspong , Elaine Lau , Nathan de Lara , Jacob Shkrob , My Duc Tran , Doina Precup , Sumana Basu

The purpose of this study is to provide means to physicians for automated and fast recognition of airways diseases. In this work, we mainly focus on measures that can be easily recorded using a spirometer. The signals used in this framework…

Machine Learning · Computer Science 2021-11-09 Riccardo Dio , André Galligo , Angelos Mantzaflaris , Benjamin Mauroy

Mechanical Ventilation (MV) is a critical life-support intervention in intensive care units (ICUs). However, optimal ventilator settings are challenging to determine because of the complexity of balancing patient-specific physiological…

Machine Learning · Computer Science 2024-12-18 Niloufar Eghbali , Tuka Alhanai , Mohammad M. Ghassemi

The choice of lung protective ventilation settings for mechanical ventilation has a considerable impact on patient outcome, yet identifying optimal ventilatory settings for individual patients remains highly challenging due to the inherent…

Respiratory diseases impose a significant burden on global health, with current diagnostic and management practices primarily reliant on specialist clinical testing. This work aims to develop machine learning-based algorithms to facilitate…

Machine Learning · Computer Science 2024-09-06 Negar Orangi-Fard , Alexandru Bogdan , Hersh Sagreiya

Objectives: The main objective of this review article is to evaluate the usability of Computational Fluid Dynamics (CFD) as a supporting clinical tool for respiratory system. Data Source: The English articles referred for this review paper…

Fluid Dynamics · Physics 2023-10-24 Rajneesh Kashyap , R. Thundil Karuppa Raj

A ventilator simulation system can make mechanical ventilation easier and more effective. As a result, predicting a patient's ventilator pressure is essential when designing a simulation ventilator. We suggested a hybrid deep learning-based…

Machine Learning · Computer Science 2023-02-21 Md. Jafril Alam , Jakaria Rabbi , Shamim Ahamed

Although mechanical ventilation is a lifesaving intervention in the ICU, it has harmful side-effects, such as barotrauma and volutrauma. These harms can occur due to asynchronies. Asynchronies are defined as a mismatch between the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 A. van Diepen , T. H. G. F. Bakkes , A. J. R. De Bie , S. Turco , R. A. Bouwman , P. H. Woerlee , M. Mischi

Energy-efficient ventilation control plays a vital role in reducing building energy consumption while ensuring occupant health and comfort. While Computational Fluid Dynamics (CFD) simulations provide detailed and physically accurate…

Systems and Control · Electrical Eng. & Systems 2025-11-20 Yuexin Bian , Oliver Schmidt , Yuanyuan Shi

Control theory provides engineers with a multitude of tools to design controllers that manipulate the closed-loop behavior and stability of dynamical systems. These methods rely heavily on insights about the mathematical model governing the…

Systems and Control · Electrical Eng. & Systems 2020-09-24 Simen Theie Havenstrøm , Camilla Sterud , Adil Rasheed , Omer San

Identifying the effects of mechanical ventilation strategies and protocols in critical care requires analyzing data from heterogeneous patient-ventilator systems within the context of the clinical decision-making environment. This research…

Quantitative Methods · Quantitative Biology 2026-01-29 David J. Albers , Tell D. Bennett , Jana de Wiljes , George Hripcsak , Bradford J. Smith , Peter D. Sottile , J. N. Stroh

We propose a robust in-time predictor for in-hospital COVID-19 patient's probability of requiring mechanical ventilation. A challenge in the risk prediction for COVID-19 patients lies in the great variability and irregular sampling of…

Machine Learning · Computer Science 2021-02-03 Kai Zhang , Siddharth Karanth , Bela Patel , Robert Murphy , Xiaoqian Jiang
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