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The issue of failed weaning is a critical concern in the intensive care unit (ICU) setting. This scenario occurs when a patient experiences difficulty maintaining spontaneous breathing and ensuring a patent airway within the first 48 hours…

Machine Learning · Computer Science 2025-03-05 Hernando Gonzalez , Carlos Julio Arizmendi , Beatriz F. Giraldo

This work presents an algorithm for determining the parameters of a nonlinear dynamic model of the respiratory system in patients undergoing assisted ventilation. Using the pressure and flow signals measured at the mouth, the model's…

Systems and Control · Electrical Eng. & Systems 2024-03-01 Diego A. Riva , Carolina A. Evangelista , Paul F. Puleston , Luis Corsiglia , Nahuel Dargains

This tutorial paper focuses on safe physics-informed machine learning in the context of dynamics and control, providing a comprehensive overview of how to integrate physical models and safety guarantees. As machine learning techniques…

Systems and Control · Electrical Eng. & Systems 2025-06-16 Jan Drgona , Truong X. Nghiem , Thomas Beckers , Mahyar Fazlyab , Enrique Mallada , Colin Jones , Draguna Vrabie , Steven L. Brunton , Rolf Findeisen

Proportional-Integral-Derivative (PID) scheme is the most commonly used algorithm for designing the controllers for unmanned aerial vehicles (UAVs). However, tuning PID gains is a non trivial task. A number of methods have been developed…

Systems and Control · Electrical Eng. & Systems 2020-04-01 Sunsoo Kim , Vedang Deshpande , Raktim Bhattacharya

The rapidly increasing prevalence of debilitating breathing disorders, such as chronic obstructive pulmonary disease (COPD), calls for a meaningful integration of artificial intelligence (AI) into healthcare. While this promises improved…

Medical Physics · Physics 2022-10-07 Harry J. Davies , Ghena Hammour , Hongjian Xiao , Danilo P. Mandic

Deep reinforcement learning (RL) has shown immense potential for learning to control systems through data alone. However, one challenge deep RL faces is that the full state of the system is often not observable. When this is the case, the…

Machine Learning · Computer Science 2023-10-27 Ian Char , Jeff Schneider

Wind resistance control is an essential feature for quadcopters to maintain their position to avoid deviation from target position and prevent collisions with obstacles. Conventionally, cascaded PID controller is used for the control of…

Robotics · Computer Science 2023-08-04 Yu Ishihara , Yuichi Hazama , Kousuke Suzuki , Jerry Jun Yokono , Kohtaro Sabe , Kenta Kawamoto

The canonical proportional-integral-derivative (PID) control approach has been widely used in industrial application due to their simplicity and ease of use. However, its corresponding controller parameters are hard to be adjusted,…

Optimization and Control · Mathematics 2020-05-05 Xiaojun Zhou

Model predictive control (MPC) is an effective method for controlling robotic systems, particularly autonomous aerial vehicles such as quadcopters. However, application of MPC can be computationally demanding, and typically requires…

Machine Learning · Computer Science 2016-02-17 Tianhao Zhang , Gregory Kahn , Sergey Levine , Pieter Abbeel

We develop a deep learning approach to predicting a set of ventilator parameters for a mechanically ventilated septic patient using a long and short term memory (LSTM) recurrent neural network (RNN) model. We focus on short-term predictions…

Quantitative Methods · Quantitative Biology 2022-02-23 Zhijun Zeng , Zhen Hou , Ting Li , Lei Deng , Jianguo Hou , Xinran Huang , Jun Li , Meirou Sun , Yunhan Wang , Qiyu Wu , Wenhao Zheng , Hua Jiang , Qi Wang

Mechanical ventilation is critical for managing respiratory failure, but inappropriate ventilator settings can lead to ventilator-induced lung injury (VILI), increasing patient morbidity and mortality. Evaluating the causal impact of…

Methodology · Statistics 2025-07-15 Ziren Jiang , Philip S. Crooke , John J. Marini , Jared D. Huling

Chronic obstructive pulmonary disease (COPD) represents a significant global health burden, where precise severity assessment is particularly critical for effective clinical management in intensive care unit (ICU) settings. This study…

Machine Learning · Computer Science 2025-04-29 Akram Shojaei , Mehdi Delrobaei

Control of an inflammatory immune response is still an ongoing research. Here, a strategy consisting of manipulating a pro and anti-inflammatory mediator is considered. Already existing and promising model-based techniques suffer…

Optimization and Control · Mathematics 2016-07-26 Ouassim Bara , Michel Fliess , Cédric Join , Judy Day , Seddik M. Djouadi

This manuscript offers the perspective of experimentalists on a number of modern data-driven techniques: model predictive control relying on Gaussian processes, adaptive data-driven control based on behavioral theory, and deep reinforcement…

Systems and Control · Electrical Eng. & Systems 2022-06-01 Loris Di Natale , Yingzhao Lian , Emilio T. Maddalena , Jicheng Shi , Colin N. Jones

Robotic catheterization is typically used for percutaneous coronary intervention procedures nowadays and it involves steering flexible endovascular tools to open up occlusion in the coronaries. In this study, a sample-efficient deep…

Robotics · Computer Science 2021-10-29 Olatunji Mumini Omisore , Toluwanimi Akinyemi , Wenke Duan , Wenjing Du , Lei Wang

Systems and machines undergo various failure modes that result in machine health degradation, so maintenance actions are required to restore them back to a state where they can perform their expected functions. Since maintenance tasks are…

Machine Learning · Computer Science 2023-07-11 Oluwaseyi Ogunfowora , Homayoun Najjaran

We present a viable prototype of a simple mechanical ventilator intended as a last resort to ventilate COVID-19 patients. The prototype implements the pressure-controlled continuous mandatory ventilation mode (PC-CMV) with settable…

The design of control engineering applications usually requires a model that accurately represents the dynamics of the real system. In addition to classical physical modeling, powerful data-driven approaches are increasingly used. However,…

Systems and Control · Electrical Eng. & Systems 2023-01-02 Annika Junker , Julia Timmermann , Ansgar Trächtler

Non-invasive estimation of respiratory physiology using computational algorithms promises to be a valuable technique for future clinicians to detect detrimental changes in patient pathophysiology. However, few clinical algorithms used to…

Quantitative Methods · Quantitative Biology 2021-09-22 Gregory Rehm , Jimmy Nguyen , Chelsea Gilbeau , Marc T Bomactao , Chen-Nee Chuah , Jason Adams

Data-driven control offers a viable option for control scenarios where constructing a system model is expensive or time-consuming. Nonetheless, many of these algorithms are not entirely automated, often necessitating the adjustment of…

Systems and Control · Electrical Eng. & Systems 2024-03-22 Riccardo Busetto , Valentina Breschi , Federica Baracchi , Simone Formentin