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Parkinson's Disease (PD) affects over 10 million people globally, with speech impairments often preceding motor symptoms by years, making speech a valuable modality for early, non-invasive detection. While recent deep-learning models…

Sound · Computer Science 2025-08-29 Terry Yi Zhong , Cristian Tejedor-Garcia , Martha Larson , Bastiaan R. Bloem

Dementia is a neurodegenerative disease that causes gradual cognitive impairment, which is very common in the world and undergoes a lot of research every year to prevent and cure it. It severely impacts the patient's ability to remember…

Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Pavan Rajkumar Magesh , Richard Delwin Myloth , Rijo Jackson Tom

Parkinson's disease (PD) is a chronic and complex neurodegenerative disorder influenced by genetic, clinical, and lifestyle factors. Predicting this disease early is challenging because it depends on traditional diagnostic methods that face…

Machine Learning · Computer Science 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Masrur Sobhan , Christian Poellabauer , Ananda Mohan Mondal

Parkinson's Disease (PD) is a chronic, degenerative disorder which leads to a range of motor and cognitive symptoms. PD diagnosis is a challenging task since its symptoms are very similar to other diseases such as normal ageing and…

Machine Learning · Computer Science 2021-01-15 Mohamad Alissa

Robust strategies for Alzheimer's disease (AD) detection are important, given the high prevalence of AD. In this paper, we study the performance and generalizability of three approaches for AD detection from speech on the recent ADReSSo…

Computation and Language · Computer Science 2022-09-16 Aparna Balagopalan , Jekaterina Novikova

This Signal Processing Grand Challenge (SPGC) targets a difficult automatic prediction problem of societal and medical relevance, namely, the detection of Alzheimer's Dementia (AD). Participants were invited to employ signal processing and…

Audio and Speech Processing · Electrical Eng. & Systems 2023-01-16 Saturnino Luz , Fasih Haider , Davida Fromm , Ioulietta Lazarou , Ioannis Kompatsiaris , Brian MacWhinney

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Background: Captured between clinical appointments using mobile devices, spoken language has potential for objective, more regular assessment of symptom severity and earlier detection of relapse in major depressive disorder. However,…

Goal: Numerous studies had successfully differentiated normal and abnormal voice samples. Nevertheless, further classification had rarely been attempted. This study proposes a novel approach, using continuous Mandarin speech instead of a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-23 Syu-Siang Wang , Chi-Te Wang , Chih-Chung Lai , Yu Tsao , Shih-Hau Fang

Speech-language pathologists (SLPs) frequently use vocal exercises in the treatment of patients with speech disorders. Patients receive treatment in a clinical setting and need to practice outside of the clinical setting to generalize…

Computers and Society · Computer Science 2016-05-23 Harishchandra Dubey , J. Cody Goldberg , Kunal Mankodiya , Leslie Mahler

Current automatic depression detection systems provide predictions directly without relying on the individual symptoms/items of depression as denoted in the clinical depression rating scales. In contrast, clinicians assess each item in the…

Parkinson disease (PD)'s speech recognition is an effective way for its diagnosis, which has become a hot and difficult research area in recent years. As we know, there are large corpuses (segments) within one subject. However, too large…

Sound · Computer Science 2021-11-18 Yiwen Wang , Fan Li , Xiaoheng Zhang , Pin Wang , Yongming Li

Depression is the most common psychological disorder and is considered as a leading cause of disability and suicide worldwide. An automated system capable of detecting signs of depression in human speech can contribute to ensuring timely…

Sound · Computer Science 2023-02-21 Mashrura Tasnim , Jekaterina Novikova

Automated speech analysis is a thriving approach to detect early markers of Alzheimer's disease (AD). Yet, recording conditions in most AD datasets are heterogeneous, with patients and controls often evaluated in different acoustic…

Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

Computation and Language · Computer Science 2020-11-21 Mireia Farrús , Joan Codina-Filbà

Automatic detection of Parkinson's disease (PD) from speech is a promising non-invasive diagnostic tool, but it raises significant privacy concerns. Speaker anonymization mitigates these risks, but it may suppress the pathological…

Sound · Computer Science 2026-03-10 Carlos Franzreb , Francisco Teixeira , Ben Luks , Sebastian Möller , Alberto Abad

Today, data collection has improved in various areas, and the medical domain is no exception. Auscultation, as an important diagnostic technique for physicians, due to the progress and availability of digital stethoscopes, lends itself well…

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Objective measurements of motor signs are of vital importance for diagnosing, monitoring and developing disease modifying…

This article describes a system for analyzing acoustic data to assist in the diagnosis and classification of children's speech sound disorders (SSDs) using a computer. The analysis concentrated on identifying and categorizing four distinct…

Sound · Computer Science 2022-07-07 Yao-Ming Kuo , Shanq-Jang Ruan , Yu-Chin Chen , Ya-Wen Tu
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