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Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Contrastive, self-supervised learning of object representations recently emerged as an attractive alternative to reconstruction-based training. Prior approaches focus on contrasting individual object representations (slots) against one…

Computer Vision and Pattern Recognition · Computer Science 2020-11-23 Sindy Löwe , Klaus Greff , Rico Jonschkowski , Alexey Dosovitskiy , Thomas Kipf

Contrastive learning between multiple views of the data has recently achieved state of the art performance in the field of self-supervised representation learning. Despite its success, the influence of different view choices has been less…

Computer Vision and Pattern Recognition · Computer Science 2020-12-21 Yonglong Tian , Chen Sun , Ben Poole , Dilip Krishnan , Cordelia Schmid , Phillip Isola

Contrastive learning is one of the fastest growing research areas in machine learning due to its ability to learn useful representations without labeled data. However, contrastive learning is susceptible to feature suppression, i.e., it may…

Machine Learning · Computer Science 2021-11-30 Tianhong Li , Lijie Fan , Yuan Yuan , Hao He , Yonglong Tian , Rogerio Feris , Piotr Indyk , Dina Katabi

We propose a self-supervised approach for learning representations of objects from monocular videos and demonstrate it is particularly useful in situated settings such as robotics. The main contributions of this paper are: 1) a…

Computer Vision and Pattern Recognition · Computer Science 2019-06-12 Sören Pirk , Mohi Khansari , Yunfei Bai , Corey Lynch , Pierre Sermanet

Protein interactions are important in a broad range of biological processes. Traditionally, computational methods have been developed to automatically predict protein interface from hand-crafted features. Recent approaches employ deep…

Machine Learning · Computer Science 2020-07-21 Yi Liu , Hao Yuan , Lei Cai , Shuiwang Ji

Deep neural networks (DNNs) have achieved remarkable success in computer vision tasks such as image classification, segmentation, and object detection. However, they are vulnerable to adversarial attacks, which can cause incorrect…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Suklav Ghosh , Sonal Kumar , Arijit Sur

Contrastive approaches to representation learning have recently shown great promise. In contrast to generative approaches, these contrastive models learn a deterministic encoder with no notion of uncertainty or confidence. In this paper, we…

Machine Learning · Computer Science 2020-10-06 Mike Wu , Noah Goodman

Chromosome recognition is an essential task in karyotyping, which plays a vital role in birth defect diagnosis and biomedical research. However, existing classification methods face significant challenges due to the inter-class similarity…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ruijia Chang , Suncheng Xiang , Chengyu Zhou , Kui Su , Dahong Qian , Jun Wang

Trajectory prediction is an essential task for successful human robot interaction, such as in autonomous driving. In this work, we address the problem of predicting future pedestrian trajectories in a first person view setting with a moving…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Marah Halawa , Olaf Hellwich , Pia Bideau

Accurate identification of drug-target interactions (DTI) remains a central challenge in computational pharmacology, where sequence-based methods offer scalability. This work introduces a sequence-based drug-target interaction framework…

Learning discriminative image representations plays a vital role in long-tailed image classification because it can ease the classifier learning in imbalanced cases. Given the promising performance contrastive learning has shown recently in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Peng Wang , Kai Han , Xiu-Shen Wei , Lei Zhang , Lei Wang

Cross entropy loss has served as the main objective function for classification-based tasks. Widely deployed for learning neural network classifiers, it shows both effectiveness and a probabilistic interpretation. Recently, after the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Rahaf Aljundi , Yash Patel , Milan Sulc , Daniel Olmeda , Nikolay Chumerin

Contrastive learning has moved the state of the art for many tasks in computer vision and information retrieval in recent years. This poster is the first work that applies supervised contrastive learning to the task of product matching in…

Machine Learning · Computer Science 2022-05-03 Ralph Peeters , Christian Bizer

Multi-view representation learning has developed rapidly over the past decades and has been applied in many fields. However, most previous works assumed that each view is complete and aligned. This leads to an inevitable deterioration in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Yiming Wang , Dongxia Chang , Zhiqiang Fu , Jie Wen , Yao Zhao

Humans perceive the world through multisensory integration, blending the information of different modalities to adapt their behavior. Contrastive learning offers an appealing solution for multimodal self-supervised learning. Indeed, by…

Machine Learning · Computer Science 2025-03-06 Benoit Dufumier , Javiera Castillo-Navarro , Devis Tuia , Jean-Philippe Thiran

Reasoning about objects, relations, and physics is central to human intelligence, and a key goal of artificial intelligence. Here we introduce the interaction network, a model which can reason about how objects in complex systems interact,…

Artificial Intelligence · Computer Science 2016-12-02 Peter W. Battaglia , Razvan Pascanu , Matthew Lai , Danilo Rezende , Koray Kavukcuoglu

Current state-of-the-art object-centric models use slots and attention-based routing for binding. However, this class of models has several conceptual limitations: the number of slots is hardwired; all slots have equal capacity; training…

Machine Learning · Computer Science 2023-11-10 Aleksandar Stanić , Anand Gopalakrishnan , Kazuki Irie , Jürgen Schmidhuber

While supervised learning has enabled great progress in many applications, unsupervised learning has not seen such widespread adoption, and remains an important and challenging endeavor for artificial intelligence. In this work, we propose…

Machine Learning · Computer Science 2019-01-23 Aaron van den Oord , Yazhe Li , Oriol Vinyals

This paper targets the problem of multi-task dense prediction which aims to achieve simultaneous learning and inference on a bunch of multiple dense prediction tasks in a single framework. A core objective in design is how to effectively…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Siwei Yang , Hanrong Ye , Dan Xu