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Tissue engineering aims to grow artificial tissues \emph{in vitro} to replace those in the body that have been damaged through age, trauma or disease. A recent approach to engineer artificial cartilage involves seeding cells within a…

Soft Condensed Matter · Physics 2017-12-05 M. J. Chen , L. S. Kimpton , J. P. Whiteley , M. Castilho , J. Malda , C. P. Please , S. L. Waters , H. M. Byrne

Scaffolds have a key role in the clinical success of tissue engineering for the regeneration of damaged tissues. Their bio-performance is often described as the extent to which they can provide an extracellular matrix-like environment for…

Biological Physics · Physics 2026-02-03 A. M. Maadani , F. Davoodian , E. Salahinejad

MRI is an indispensable clinical tool, offering a rich variety of tissue contrasts to support broad diagnostic and research applications. Clinical exams routinely acquire multiple structural sequences that provide complementary information…

Image and Video Processing · Electrical Eng. & Systems 2025-10-03 Tolga Çukur , Salman U. H. Dar , Valiyeh Ansarian Nezhad , Yohan Jun , Tae Hyung Kim , Shohei Fujita , Berkin Bilgic

Brillouin imaging is increasingly recognized to be a powerful technique that enables non-invasive measurement of the mechanical properties of cells and tissues on a microscopic scale. This provides an unprecedented tool for investigating…

Biological Physics · Physics 2020-01-22 Christine Poon , Joshua Chou , Michael Cortie , Irina Kabakova

Synthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.…

Modern spatial microscopy has provided developmental biology with powerful research tools. However, the recent significant technological breakthroughs have inevitably led to technical "bottlenecks" for the application of the new procedures…

Quantitative Methods · Quantitative Biology 2012-05-02 Ivan V. Rudskiy , Nadejda V. Khodorova

In this article we highlight chemotaxis (cellular movement) as a rich source of potential engineering applications and computational models, highlighting current research and possible future work. We first give a brief description of the…

Cell Behavior · Quantitative Biology 2007-05-23 Martyn Amos , David A. Hodgson , Alan Gibbons

The challenge of translating vast, multimodal biological data into predictive and mechanistic understanding of cellular function is a central theme in modern biology. Virtual cells, or digital cellular twins, have emerged as a critical…

Quantitative Methods · Quantitative Biology 2025-09-24 Saurabh Bhardwaj , Gaurav Kumar , Haochen Yang , Shaurya Bhardwaj , Qun Wang , Minjie Shen , Yizhi Wang , Cristabelle Madona De Souza

Optically transparent wound dressings offer a range of potential applications in the biomedical field, as they allow for the monitoring of wound healing progress without having to replace the dressing. These dressings must be impermeable to…

Biomolecules · Quantitative Biology 2023-06-28 Muzammil Kuddushi , Aatif Ali Shah , Cagri Ayranci , Xuehua Zhanga

In recent years, machine learning algorithms have achieved much success in segmenting lesions across various tissues. There is, however, not one satisfying model that works well on all tissue types universally. In response to this need, we…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Kaiwen Shi , Yifei Li , Binh Ho , Jovian Wang , Kobe Guo

Robotic systems are increasingly used in rehabilitation to provide high intensity training for patients with motor impairment. The results of controlled trials involving human subjects confirm the effectiveness of robot-enhanced methods and…

Robotics · Computer Science 2017-12-20 Rana Soltani-Zarrin , Amin Zeiaee , Reza Langari , Reza Tafreshi

As the potential for neural networks to augment our daily lives grows, ensuring their quality through effective testing, debugging, and maintenance is essential. This is especially the case as we acknowledge the prospects of negative…

Software Engineering · Computer Science 2025-07-08 Fatema Tuz Zohra , Brittany Johnson

As an effective method to deliver external materials into biological cells, microinjection has been widely applied in the biomedical field. However, the cognition of cell mechanical property is still inadequate, which greatly limits the…

Robotics · Computer Science 2022-11-29 Shengzheng Kang , Zhicheng Song , Xiaolong Yang , Yao Li , Hongtao Wu , Tao Li

Spine biomechanics is at a transformation with the advent and integration of machine learning and computer vision technologies. These novel techniques facilitate the estimation of 3D body shapes, anthropometrics, and kinematics from as…

The human body is mysterious, consisting of innumerable fine and complex structures and a vast amount of information. The field of modern pathology has been systematized around the findings and observations obtained from light microscopy.…

Medical Physics · Physics 2021-11-29 Satoshi Kume

Microbes and pathogens play a detrimental role in healing wounds, causing infections like impetigo through bodily fluids and skin and entering the bloodstream through the wounds, thereby hindering the healing process and tissue…

Biomolecules · Quantitative Biology 2025-02-24 Suvash Ghimire , Yi Wu , Manjyot Kaur Chug , Elizabeth J. Brisbois , Kyungtae Kim , Kausik Mukhopadhyay

In this article, a new conceptual biomedical engineering strategy to tackle modern disease challenges, termed as liquid metal enabled electrobiology, is proposed. This generalized and easy going way is based on the physiological fact that…

Medical Physics · Physics 2018-05-11 Xuelin Wang , Yi Ren , Jing Liu

A new strategy with bone tissue engineering by mesenchymal stem cell transplantation on titanium implant has been dawn attention. The surface scaffold properties of titanium surface play an important role in bone regenerative potential of…

Cell Behavior · Quantitative Biology 2010-05-03 Yukimichi Tamaki , Yu Kataoka , Takashi Miyazaki

The application of single-cell molecular profiling coupled with spatial technologies has enabled charting cellular heterogeneity in reference tissues and in disease. This new wave of molecular data has highlighted the expected diversity of…

Tissues and Organs · Quantitative Biology 2024-03-12 Ricardo Omar Ramirez Flores , Philipp Sven Lars Schäfer , Leonie Küchenhoff , Julio Saez-Rodriguez

When they are damaged or injured, soft biological tissues are able to self-repair and heal. Mechanics is critical during the healing process, as the damaged extracellular matrix (ECM) tends to be replaced with a new undamaged ECM supporting…

Computational Engineering, Finance, and Science · Computer Science 2021-12-08 Di Zuo , Yiqian He , Stéphane Avril , Haitian Yang , Klaus Hackl