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In recent years, four-dimensional (4D) fabrication has emerged as a powerful technology capable of revolutionizing the field of tissue engineering. This technology represents a shift in perspective from traditional tissue engineering…

Medical Physics · Physics 2025-01-15 Lorenzo Bonetti , Giulia Scalet

Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in…

Medical Physics · Physics 2024-11-14 Feng Zhao , Yizhou Wu , Mingzhe Hu , Chih-Wei Chang , Ruirui Liu , Richard Qiu , Xiaofeng Yang

The biomaterials exploitation in a sophisticated manner can provide extensive opportunities for experimentation in the field of interdisciplinary and multidisciplinary scientific research. Owing to the unique features of this trendy area,…

Applied Physics · Physics 2018-03-19 Hafiz M. N. Iqbal

In the field of biomedical imaging, ultrasonography has become increasingly widespread, and an important auxiliary diagnostic tool with unique advantages, such as being non-ionising and often portable. This article reviews the…

Signal Processing · Electrical Eng. & Systems 2022-11-08 Tianqi Yang , Oktay Karakuş , Nantheera Anantrasirichai , Alin Achim

During embryonic morphogenesis, tissues undergo dramatic deformations in order to form functional organs. Similarly, in adult animals, living cells and tissues are continually subjected to forces and deformations. Therefore, the success of…

Soft Condensed Matter · Physics 2024-05-06 Michael J. Hertaeg , Suzanne M. Fielding , Dapeng Bi

With many advancements in in silico biology in recent years, the paramount challenge is to translate the accumulated knowledge into exciting industry partnerships and clinical applications. Achieving models that characterize the link of…

Quantitative Methods · Quantitative Biology 2023-06-06 Michael Taynnan Barros , Michelangelo Paci , Aapo Tervonen , Elisa Passini , Jussi Koivumäki , Jari Hyttinen , Kerstin Lenk

There is an increase in demand for organs as transplantation is becoming a common practice to elongate human life. To reach this demand, three-dimensional bioprinting is developing from prior knowledge of scaffolds, growth factors, etc.…

Tissues and Organs · Quantitative Biology 2022-12-29 Alicia Shin

Biomaterials are becoming an essential tool in the study and application of stem cell research. Various types of biomaterials enable three-dimensional (3D) culture of stem cells, and, more recently, also enable high-resolution patterning…

Tissues and Organs · Quantitative Biology 2016-10-11 Richard J. McMurtrey

The periodontal biomechanical environment is very difficult to investigate. By the complex geometry and composition of the periodontal ligament, its mechanical behavior is very dependent on the type of loading (compressive vs. tensile…

The last decade has witnessed a rapid growth in understanding of the pivotal roles of mechanical stresses and physical forces in cell biology. As a result an integrated view of cell biology is evolving, where genetic and molecular features…

Soft Condensed Matter · Physics 2021-10-08 Amin Doostmohammadi , Benoit Ladoux

Neuromorphic computing and engineering has been the focus of intense research efforts that have been intensified recently by the mutation of Information and Communication Technologies (ICT). In fact, new computing solutions and new hardware…

Applied Physics · Physics 2018-10-09 Sebastien Pecqueur , Dominique Vuillaume , Fabien Alibart

The scarcity of organs for transplant has led to large waiting lists of very sick patients. In drug development, the time required for human trials greatly increases the time to market. Drug companies are searching for alternative…

Tissues and Organs · Quantitative Biology 2015-07-28 Ali Bakhshinejad , Roshan M D'Souza

Cultured meat has the potential to provide a complementary meat industry with reduced environmental, ethical, and health impacts. However, major technological challenges remain which require time- and resource-intensive research and…

Computers and Society · Computer Science 2024-10-24 Michael E. Todhunter , Sheikh Jubair , Ruchika Verma , Rikard Saqe , Kevin Shen , Breanna Duffy

Biological engineering, the convergence between engineering and biology, is at the forefront of significant advances in healthcare, agriculture, and environmental sustainability, making it highly relevant to current scientific and societal…

Other Quantitative Biology · Quantitative Biology 2026-02-17 Ulrike A. Nuber , Viktor Stein

Tissue biopsy is the gold standard for diagnosing many diseases, involving the extraction of diseased tissue for histopathology analysis by expert pathologists. However, this procedure has two main limitations: 1) Manual sampling through…

Robotics · Computer Science 2025-09-03 Fanxin Wang , Yikun Cheng , Chuyuan Tao , Rohit Bhargava , Thenkurussi Kesavadas

The science and clinical practice of medical physics has been integral to the advancement of radiology and radiation therapy for over a century. In parallel, advances in surgery - including intraoperative imaging, registration, and other…

Medical Physics · Physics 2025-09-04 Jeffrey H. Siewerdsen

Cells segmentation shows rapid growth in biology. Indeed, using the classical segmentation methods only is not enough to segment this type of images. In this manuscript, we will present a new method of ribosomes segmentation. A…

Image and Video Processing · Electrical Eng. & Systems 2021-01-14 Mariam El Oussini

Systems Biology has emerged in the last years as a new holistic approach based on the global understanding of cells instead of only being focused on their individual parts (genes or proteins), to better understand the complexity of human…

The evolution of various competing cell types in tissues, and the resulting persistent tissue population, is studied numerically and analytically in a particle-based model of active tissues. Mutations change the properties of cells in…

Populations and Evolution · Quantitative Biology 2024-06-03 Tobias Büscher , Nirmalendu Ganai , Gerhard Gompper , Jens Elgeti

Robotic technology has the potential to revolutionize the field of neurology by providing new methods for diagnosis, treatment, and rehabilitation of neurological disorders. In recent years, there has been an increasing interest in the…