English
Related papers

Related papers: Cryo-shift: Reducing domain shift in cryo-electron…

200 papers

Advances in imagery at atomic and near-atomic resolution, such as cryogenic electron microscopy (cryo-EM), have led to an influx of high resolution images of proteins and other macromolecular structures to data banks worldwide. Producing a…

Quantitative Methods · Quantitative Biology 2021-04-06 Nathan Ranno , Dong Si

Deep learning methods have shown promise in unsupervised domain adaptation, which aims to leverage a labeled source domain to learn a classifier for the unlabeled target domain with a different distribution. However, such methods typically…

Computer Vision and Pattern Recognition · Computer Science 2019-10-10 Zhijie Deng , Yucen Luo , Jun Zhu

Aiming towards human-level generalization, there is a need to explore adaptable representation learning methods with greater transferability. Most existing approaches independently address task-transferability and cross-domain adaptation,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Jogendra Nath Kundu , Nishank Lakkakula , R. Venkatesh Babu

In this paper, we introduce a novel unsupervised domain adaptation technique for the task of 3D keypoint prediction from a single depth scan or image. Our key idea is to utilize the fact that predictions from different views of the same or…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Xingyi Zhou , Arjun Karpur , Chuang Gan , Linjie Luo , Qixing Huang

Despite the widespread use of deep learning methods for semantic segmentation of images that are acquired from a single source, clinicians often use multi-domain data for a detailed analysis. For instance, CT and MRI have advantages over…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Bora Baydar , Savas Ozkan , A. Emre Kavur , N. Sinem Gezer , M. Alper Selver , Gozde Bozdagi Akar

Unsupervised Domain Adaptive Object Detection (UDA-OD) uses unlabelled data to improve the reliability of robotic vision systems in open-world environments. Previous approaches to UDA-OD based on self-training have been effective in…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Nicolas Harvey Chapman , Feras Dayoub , Will Browne , Christopher Lehnert

Many imaging modalities involve reconstruction of unknown objects from collections of noisy projections related by random rotations. In one of these modalities, cryogenic electron microscopy (cryo-EM), the extremely low signal-to-noise…

Image and Video Processing · Electrical Eng. & Systems 2025-10-16 Joakim Andén , Justus Sagemüller

Domain Adaptation is a technique to address the lack of massive amounts of labeled data in unseen environments. Unsupervised domain adaptation is proposed to adapt a model to new modalities using solely labeled source data and unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Thong Vo , Naimul Khan

Knowledge of a protein's atomic conformational ensemble is critical to determining its function, yet state-of-the-art ensemble prediction models are limited by lack of high-quality conformational data from simulation or experiment. Recent…

Machine Learning · Computer Science 2026-05-12 Jay Shenoy , Miro Astore , Axel Levy , Frédéric Poitevin , Sonya M. Hanson , Gordon Wetzstein

High-resolution structure determination by cryo-electron microscopy (cryo-EM) requires the accurate fitting of an atomic model into an experimental density map. Traditional refinement pipelines such as Phenix.real_space_refine and Rosetta…

Biomolecules · Quantitative Biology 2026-03-10 Fuyao Huang , Xiaozhu Yu , Kui Xu , Qiangfeng Cliff Zhang

In this paper, we tackle the problem of domain shift. Most existing methods perform training on multiple source domains using a single model, and the same trained model is used on all unseen target domains. Such solutions are sub-optimal as…

Machine Learning · Computer Science 2023-01-13 Tao Zhong , Zhixiang Chi , Li Gu , Yang Wang , Yuanhao Yu , Jin Tang

Cryogenic electron microscopy (Cryo-EM) has become an essential tool for capturing high-resolution biological structures. Despite its advantage in visualizations, the large storage size of Cryo-EM data file poses significant challenges for…

Machine Learning · Computer Science 2025-12-16 Chunyu Zou

Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approach that learns individual particle orientations from cryo-EM…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Youssef S. G. Nashed , Frederic Poitevin , Harshit Gupta , Geoffrey Woollard , Michael Kagan , Chuck Yoon , Daniel Ratner

In this work, we explore the usage of the Frequency Transformation for reducing the domain shift between the source and target domain (e.g., synthetic image and real image respectively) towards solving the Domain Adaptation task. Most of…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Vikash Kumar , Himanshu Patil , Rohit Lal , Anirban Chakraborty

Digitization techniques for biomedical images yield different visual patterns in radiological exams. These differences may hamper the use of data-driven approaches for inference over these images, such as Deep Neural Networks. Another…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Hugo Oliveira , Edemir Ferreira , Jefersson A. dos Santos

End-to-end learning methods have achieved impressive results in many areas of computer vision. At the same time, these methods still suffer from a degradation in performance when testing on new datasets that stem from a different…

Computer Vision and Pattern Recognition · Computer Science 2016-03-24 Rahaf Aljundi , Tinne Tuytelaars

Unsupervised domain adaptation aims to transfer knowledge from a labeled source domain to an unlabeled target domain. Previous methods focus on learning domain-invariant features to decrease the discrepancy between the feature distributions…

Machine Learning · Computer Science 2021-06-30 Yuntao Du , Yinghao Chen , Fengli Cui , Xiaowen Zhang , Chongjun Wang

In this paper, we propose a novel unsupervised domain adaptation algorithm based on deep learning for visual object recognition. Specifically, we design a new model called Deep Reconstruction-Classification Network (DRCN), which jointly…

Computer Vision and Pattern Recognition · Computer Science 2016-08-03 Muhammad Ghifary , W. Bastiaan Kleijn , Mengjie Zhang , David Balduzzi , Wen Li

Electron cryo-tomography (cryo-ET) enables 3D imaging of complex, radiation-sensitive structures with molecular detail. However, image contrast from the interference of scattered electrons is nonlinear with atomic density and multiple…

Automated experiments in scanning transmission electron microscopy (STEM) require rapid image segmentation to optimize data representation for human interpretation, decision-making, site-selective spectroscopies, and atomic manipulation.…

Materials Science · Physics 2024-09-23 Kamyar Barakati , Utkarsh Pratiush , Austin C. Houston , Gerd Duscher , Sergei V. Kalinin