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Related papers: Proton radiographs using position-sensitive silico…

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Proton radiography is a central diagnostic technique for measuring electromagnetic (EM) fields in high-energy-density, laser-produced plasmas. In this technique, protons traverse the plasma where they accumulate small EM deflections which…

Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

Protontherapy is hadrontherapy fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct…

Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…

Medical Physics · Physics 2025-08-06 Hunter D. Ellis , Imteaz Rahaman , Apostoli Hillas , Botong Li , Vikren Sarkar , Kai Fu

In this work, we report on the advantageous aspects of the i-TED Compton imager for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that…

The determination of relative stopping power (RSP) via proton computed tomography (pCT) of a patient is dependent in part on the knowledge of the incoming proton kinetic energies; the uncertainty in these energies is in turn determined by…

This article examines the critical role of fast Monte Carlo dose calculations in advancing proton therapy techniques, particularly in the context of increasing treatment customization and precision. As adaptive radiotherapy and other…

Medical Physics · Physics 2024-04-24 Jason Holmes , Hongying Feng , Lian Zhang , Michael Fix , Steve B. Jiang , Wei Liu

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

We present a nitrogen-targeting-Proton-Carbon-Alpha-Therapy method, abbreviated as Proton-CAT, which partially converts protons into carbon-12 and $\alpha$ particles through nuclear reactions between protons and nitrogen-15. Monte Carlo…

Proton radiography is a new scatheless diagnostic tool, and which provides a potential development direction for advanced hydrotesting. Recently a low energy proton radiography system has been developed at CAEP. This system has been…

Accelerator Physics · Physics 2013-10-22 Tao Wei , Guojun Yang , Jidong Long , Xiaozhong He , Yiding Li , Xiaoding Zhang , Chaofan Ma , Liangchao Zhao , Jinshui Shi

Cancer therapy using protons and heavier ions such as carbon has demonstrated advantages over other radiotherapy treatments. To bring about the next generation of clinical facilities, the requirements are likely to reduce the footprint,…

Accelerator Physics · Physics 2021-05-19 H. X. Q. Norman , A. F. Steinberg , R. B. Appleby , H. L. Owen , E. Benedetto , M. Sapinski , S. L. Sheehy

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

Purpose: To improve target coverage and reduce the dose in the surrounding organs-at-risks (OARs), we developed an image-guided treatment method based on a precomputed library of treatment plans controlled and delivered in real-time.…

Medical Physics · Physics 2022-11-02 Valentin Hamaide , Kevin Souris , Damien Dasnoy , Francois Glineur , Benoit Macq

Objective: Proton therapy is a precision-focused cancer treatment where accurate proton beam range monitoring is critical to ensure effective dose delivery. This can be achieved by prompt gamma detection with a Compton camera like the…

We have used an inexpensive 3D printer mounting an inexpensive pre-irradiated silicon diode to measure the 2D dose distribution of a small (approximately 10mm FWHM) proton beam. z was measured with high resolution whereas x was changed on a…

Instrumentation and Detectors · Physics 2019-08-13 Ethan W. Cascio , Bernard Gottschalk

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…

Proton computed tomography (pCT) is an image modality that will improve treatment planning for patients receiving proton radiation therapy compared with the current treatment techniques, which are based on X-ray CT. Reconstruction of a pCT…

Medical Physics · Physics 2021-08-30 Micah Witt , Blake Schultze , Reinhard Schulte , Keith Schubert , Ernesto Gomez

Hadron therapy is a novel treatment against cancer. The main advantage of this therapy causes less side effect in comparison to X-ray irradiation methods. Hadron therapy is just ahead of a significant breakthrough since this technique can…

Instrumentation and Detectors · Physics 2020-05-07 Ákos Sudár

Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…

Hadron therapy, because of the dosimetric and radiobiological advantages, is more and more often used in tumour treatment. This treatment method leads also to the radioactive effects induced by energetic protons on nuclei. Nuclear reactions…

Medical Physics · Physics 2018-04-26 Przemysław Sękowski , Izabela Skwira-Chalot , Tomasz Matulewicz