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Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

The past decade has seen a substantial rise in the amount of mis- and disinformation online, from targeted disinformation campaigns to influence politics, to the unintentional spreading of misinformation about public health. This…

Computation and Language · Computer Science 2021-12-09 Isabelle Augenstein

There is a growing concern about typically opaque decision-making with high-performance machine learning algorithms. Providing an explanation of the reasoning process in domain-specific terms can be crucial for adoption in risk-sensitive…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Aditya Chattopadhyay , Stewart Slocum , Benjamin D. Haeffele , Rene Vidal , Donald Geman

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

The success of neural networks builds to a large extent on their ability to create internal knowledge representations from real-world high-dimensional data, such as images, sound, or text. Approaches to extract and present these…

Artificial Intelligence · Computer Science 2023-01-03 Lars Holmberg , Paul Davidsson , Per Linde

In 2019, The Centers for Medicare and Medicaid Services (CMS) launched an Artificial Intelligence (AI) Health Outcomes Challenge seeking solutions to predict risk in value-based care for incorporation into CMS Innovation Center payment and…

Machine Learning · Computer Science 2021-05-21 Chuhong Lahlou , Ancil Crayton , Caroline Trier , Evan Willett

Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques…

Machine Learning · Computer Science 2022-09-15 Flavio Di Martino , Franca Delmastro

The use of convolutional neural networks (CNNs) for classification tasks has become dominant in various medical imaging applications. At the same time, recent advances in interpretable machine learning techniques have shown great potential…

Image and Video Processing · Electrical Eng. & Systems 2019-10-02 Irina Grigorescu , Lucilio Cordero-Grande , A David Edwards , Jo Hajnal , Marc Modat , Maria Deprez

Recent powerful pre-trained language models have achieved remarkable performance on most of the popular datasets for reading comprehension. It is time to introduce more challenging datasets to push the development of this field towards more…

Computation and Language · Computer Science 2020-08-25 Weihao Yu , Zihang Jiang , Yanfei Dong , Jiashi Feng

While recently developed NLP explainability methods let us open the black box in various ways (Madsen et al., 2022), a missing ingredient in this endeavor is an interactive tool offering a conversational interface. Such a dialogue system…

Computation and Language · Computer Science 2023-10-24 Nils Feldhus , Qianli Wang , Tatiana Anikina , Sahil Chopra , Cennet Oguz , Sebastian Möller

Recent advances in machine learning have led to a surge in adoption of neural networks for various tasks, but lack of interpretability remains an issue for many others in which an understanding of the features influencing the prediction is…

Clinical case formulation organizes patient symptoms and psychosocial factors into causal models, often using the 5P framework. However, constructing such graphs from therapy transcripts is time consuming and varies across clinicians. We…

Computation and Language · Computer Science 2026-04-15 Shreya Gupta , Prottay Kumar Adhikary , Bhavyaa Dave , Salam Michael Singh , Aniket Deroy , Tanmoy Chakraborty

Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…

Machine Learning · Computer Science 2019-08-08 Sana Tonekaboni , Shalmali Joshi , Melissa D McCradden , Anna Goldenberg

Deep learning as represented by the artificial deep neural networks (DNNs) has achieved great success in many important areas that deal with text, images, videos, graphs, and so on. However, the black-box nature of DNNs has become one of…

Machine Learning · Computer Science 2021-09-29 Fenglei Fan , Jinjun Xiong , Mengzhou Li , Ge Wang

The success of neural networks comes hand in hand with a desire for more interpretability. We focus on text classifiers and make them more interpretable by having them provide a justification, a rationale, for their predictions. We approach…

Computation and Language · Computer Science 2020-06-22 Jasmijn Bastings , Wilker Aziz , Ivan Titov

Medical AI, including clinical language models, vision-language models, and multimodal health record models, already summarizes notes, answers questions, and supports decisions. Their adaptation to new populations, specialties, or care…

Artificial Intelligence · Computer Science 2025-12-01 Michelle M. Li , Ben Y. Reis , Adam Rodman , Tianxi Cai , Noa Dagan , Ran D. Balicer , Joseph Loscalzo , Isaac S. Kohane , Marinka Zitnik

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

The widespread application of pre-trained language models (PLMs) in natural language processing (NLP) has led to increasing concerns about their explainability. Selective rationalization is a self-explanatory framework that selects…

Computation and Language · Computer Science 2025-01-07 Libing Yuan , Shuaibo Hu , Kui Yu , Le Wu

Extracting information from electronic health records (EHR) is a challenging task since it requires prior knowledge of the reports and some natural language processing algorithm (NLP). With the growing number of EHR implementations, such…

Machine Learning · Computer Science 2019-08-02 Sanghyun Choi , Nikita Ivkin , Vladimir Braverman , Michael A. Jacobs