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This work introduces a novel approach to study properties of positive equilibria of a chemical reaction network $\mathscr{N}$ endowed with Hill-type kinetics $K$, called a Hill-type kinetic (HTK) system $\left(\mathscr{N},K\right)$,…

Dynamical Systems · Mathematics 2020-09-08 Bryan S. Hernandez , Eduardo R. Mendoza

Poly-PL kinetic systems (PYK) are kinetic systems consisting of nonnegative linear combinations of power law functions. In this contribution, we analyze these kinetic systems using two main approaches: (1) we define a canonical power law…

Dynamical Systems · Mathematics 2021-12-24 Editha C. Jose , Eduardo R. Mendoza , Dylan Antonio SJ. Talabis

There have been recent theoretic results that provide sufficient conditions for the existence of a species displaying absolute concentration robustness (ACR) in a power law kinetic (PLK) system. One such result involves the detection of ACR…

Chemical Physics · Physics 2020-11-06 Lauro L. Fontanil , Eduardo R. Mendoza , Noel T. Fortun

Robustness against the presence of environmental disruptions can be observed in many systems of chemical reaction network. However, identifying the underlying components of a system that give rise to robustness is often elusive. The…

Dynamical Systems · Mathematics 2020-03-31 Noel T. Fortun , Angelyn R. Lao , Luis F. Razon , Eduardo R. Mendoza

Poly-PL kinetic systems are kinetic systems consisting of nonnegative linear combinations of power law functions. In this contribution, we analyze these kinetic systems using two main approaches: (1) we define a canonical power law…

Dynamical Systems · Mathematics 2021-07-13 Noel T. Fortun , Dylan Antonio SJ. Talabis , Editha C. Jose , Eduardo R. Mendoza

For a reaction network with species set $\mathscr{S}$, a log-parametrized (LP) set is a non-empty set of the form $E(P, x^*) = \{x \in \mathbb{R}^\mathscr{S}_> \mid \log x - \log x^* \in P^\perp\}$ where $P$ (called the LP set's flux…

Algebraic Geometry · Mathematics 2021-10-27 Angelyn R. Lao , Patrick Vincent N. Lubenia , Daryl M. Magpantay , Eduardo R. Mendoza

A complex balanced kinetic system is absolutely complex balanced (ACB) if every positive equilibrium is complex balanced. Two results on absolute complex balancing were foundational for modern chemical reaction network theory (CRNT): in…

Dynamical Systems · Mathematics 2021-12-28 Editha C. Jose , Eduardo R. Mendoza , Dylan Antonio SJ. Talabis

One important question that interests those who work in chemical reaction network theory (CRNT) is this: Does the system obtained from a reaction network admit a positive equilibrium and if it does, can there be more than one within a…

This paper studies chemical kinetic systems which decompose into weakly reversible complex factorizable (CF) systems. Among power law kinetic systems, CF systems (denoted as PL-RDK systems) are those where branching reactions of a reactant…

Dynamical Systems · Mathematics 2022-03-08 Bryan S. Hernandez , Eduardo R. Mendoza

This paper presents a computational solution to determine if a chemical reaction network endowed with power-law kinetics (PLK system) has the capacity for multistationarity, i.e., whether there exist positive rate constants such that the…

Dynamical Systems · Mathematics 2020-02-19 Bryan S. Hernandez , Eduardo R. Mendoza , Aurelio A. de los Reyes

Power law systems have been studied extensively due to their wide-ranging applications, particularly in chemistry. In this work, we focus on power law systems that can be decomposed into stoichiometrically independent subsystems. We show…

Dynamical Systems · Mathematics 2024-04-23 Al Jay Lan J. Alamin , Bryan S. Hernandez

Closed-loop positivity of feedback interconnections of positive monotone nonlinear systems is investigated. It is shown that an instantaneous gain condition on the open-loop systems which implies feedback well-posedness also guarantees…

Optimization and Control · Mathematics 2015-08-27 Sei Zhen Khong , Corentin Briat , Anders Rantzer

A decomposition of a chemical reaction network (CRN) is produced by partitioning its set of reactions. The partition induces networks, called subnetworks, that are "smaller" than the given CRN which, at this point, can be called parent…

Molecular Networks · Quantitative Biology 2021-09-15 Lauro L. Fontanil , Eduardo R. Mendoza

Dynamical systems arising from chemical reaction networks with mass action kinetics are the subject of chemical reaction network theory (CRNT). In particular, this theory provides statements about uniqueness, existence, and stability of…

Dynamical Systems · Mathematics 2014-06-26 Stefan Müller , Georg Regensburger

Mass action systems capture chemical reaction networks in homogeneous and dilute solutions. We suggest a notion of generalized mass action systems that admits arbitrary nonnegative power-law rate functions and serves as a more realistic…

Dynamical Systems · Mathematics 2013-08-15 Stefan Müller , Georg Regensburger

Absolute concentration robustness (ACR) is a condition wherein a species in a chemical kinetic system possesses the same value for any positive steady state the network may admit regardless of initial conditions. Thus far, results on ACR…

Dynamical Systems · Mathematics 2020-04-02 Noel T. Fortun , Eduardo R. Mendoza

Chemical reaction networks with generalized mass-action kinetics lead to power-law dynamical systems. As a simple example, we consider the Lotka reactions with two chemical species and arbitrary power-law kinetics. We study existence,…

Dynamical Systems · Mathematics 2022-09-14 Balázs Boros , Josef Hofbauer , Stefan Müller

We present conditions which guarantee a parametrization of the set of positive equilibria of a generalized mass-action system. Our main results state that (i) if the underlying generalized chemical reaction network has an effective…

Dynamical Systems · Mathematics 2018-05-24 Matthew D. Johnston , Stefan Müller , Casian Pantea

In this letter we introduce a class of delayed kinetic systems derived from mass action type reaction network models. We define the time delayed positive stoichiometric compatibility classes and the notion of complex balanced time delayed…

Dynamical Systems · Mathematics 2017-04-21 György Lipták , Katalin M. Hangos , Mihály Pituk , Gábor Szederkényi

This paper addresses the modeling and control of heterogeneous populations of thermostatically controlled loads (TCLs) operated by model predictive control (MPC) schemes at level of each TCL. It is shown that the dynamics of such TCLs…

Optimization and Control · Mathematics 2019-12-24 Jun Zheng , Gabriel Laparra , Guchuan Zhu , Meng Li
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