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Interpretable classification models are built with the purpose of providing a comprehensible description of the decision logic to an external oversight agent. When considered in isolation, a decision tree, a set of classification rules, or…

Machine Learning · Computer Science 2019-03-18 Riccardo Guidotti , Salvatore Ruggieri

Deep neural networks have shown impressive performance for image-based disease detection. Performance is commonly evaluated through clinical validation on independent test sets to demonstrate clinically acceptable accuracy. Reporting good…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Mobarakol Islam , Zeju Li , Ben Glocker

Deep neural networks are behind many of the recent successes in machine learning applications. However, these models can produce overconfident decisions while encountering out-of-distribution (OOD) examples or making a wrong prediction.…

Machine Learning · Computer Science 2021-06-24 Navid Kardan , Ankit Sharma , Kenneth O. Stanley

The interpretation of medical images is a challenging task, often complicated by the presence of artifacts, occlusions, limited contrast and more. Most notable is the case of chest radiography, where there is a high inter-rater variability…

This paper establishes fundamental results for statistical inference of diagnostic classification models (DCM). The results are developed at a high level of generality, applicable to essentially all diagnostic classification models. In…

Statistics Theory · Mathematics 2025-01-08 Guanhua Fang , Jingchen Liu , Zhiliang Ying

Medical imaging classifiers can achieve high predictive accuracy, but quantifying their uncertainty remains an unresolved challenge, which prevents their deployment in medical clinics. We present an algorithm that can modify any classifier…

Machine Learning · Computer Science 2024-08-12 Roy Hirsch , Jacob Goldberger

Individuals use models to guide decisions, but many models are wrong. This paper studies which misspecified models are likely to persist when individuals also entertain alternative models. Consider an agent who uses her model to learn the…

Theoretical Economics · Economics 2023-08-22 Cuimin Ba

Consistency models, which were proposed to mitigate the high computational overhead during the sampling phase of diffusion models, facilitate single-step sampling while attaining state-of-the-art empirical performance. When integrated into…

Machine Learning · Statistics 2024-02-13 Gen Li , Zhihan Huang , Yuting Wei

The identification and quantification of markers in medical images is critical for diagnosis, prognosis and management of patients in clinical practice. Supervised- or weakly supervised training enables the detection of findings that are…

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

In this review we make the statement that hybrid models in oncology are required as a mean for enhanced data integration. In the context of systems oncology, experimental and clinical data need to be at the heart of the models developments…

Quantitative Methods · Quantitative Biology 2019-01-18 Angélique Stéphanou , Pascal Ballet , Gibin Powathil

We present machine-learning-based approaches for determining the \emph{degree} of inconsistency -- which is a numerical value -- for propositional logic knowledge bases. Specifically, we present regression- and neural-based models that…

Artificial Intelligence · Computer Science 2025-02-06 Sven Weinzierl , Carl Cora

Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

With the maturing of deep learning systems, trustworthiness is becoming increasingly important for model assessment. We understand trustworthiness as the combination of explainability and robustness. Generative classifiers (GCs) are a…

Computer Vision and Pattern Recognition · Computer Science 2020-12-03 Radek Mackowiak , Lynton Ardizzone , Ullrich Köthe , Carsten Rother

Recent advances in artificial intelligence have witnessed the emergence of large-scale deep learning models capable of interpreting and generating both textual and imaging data. Such models, typically referred to as foundation models, are…

Recent advances in machine learning for medical imaging have led to impressive increases in model complexity and overall capabilities. However, the ability to discern the precise information a machine learning method is using to make…

Machine Learning · Computer Science 2020-03-17 Tatiana Fountoukidou , Raphael Sznitman

An integrated approach is proposed across visual and textual data to both determine and justify a medical diagnosis by a neural network. As deep learning techniques improve, interest grows to apply them in medical applications. To enable a…

Machine Learning · Computer Science 2019-07-15 Graham Spinks , Marie-Francine Moens

Mammographic screening is an effective method for detecting breast cancer, facilitating early diagnosis. However, the current need to manually inspect images places a heavy burden on healthcare systems, spurring a desire for automated…

Image and Video Processing · Electrical Eng. & Systems 2025-01-30 Ciaran Bench , Emir Ahmed , Spencer A. Thomas

We present new results for consistency of maximum likelihood estimators with a focus on multivariate mixed models. Our theory builds on the idea of using subsets of the full data to establish consistency of estimators based on the full…

Statistics Theory · Mathematics 2019-02-13 Karl Oskar Ekvall , Galin L. Jones