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Machine learning models can be used to predict physical quantities like homogenized elasticity stiffness tensors, which must always be symmetric positive definite (SPD) based on conservation arguments. Two datasets of homogenized elasticity…

Machine Learning · Computer Science 2022-03-29 Charles F. Jekel , Kenneth E. Swartz , Daniel A. White , Daniel A. Tortorelli , Seth E. Watts

Expert diagnostic support systems have been extensively studied. The practical applications of these systems in real-world scenarios have been somewhat limited due to well-understood shortcomings, such as lack of extensibility. More…

Artificial Intelligence · Computer Science 2018-08-15 Murali Ravuri , Anitha Kannan , Geoffrey J. Tso , Xavier Amatriain

Sequence classification is the supervised learning task of building models that predict class labels of unseen sequences of symbols. Although accuracy is paramount, in certain scenarios interpretability is a must. Unfortunately, such…

Machine Learning · Computer Science 2020-06-26 Severin Gsponer , Luca Costabello , Chan Le Van , Sumit Pai , Christophe Gueret , Georgiana Ifrim , Freddy Lecue

Uncertainty quantification complements model predictions by characterizing their reliability, which is essential for high-stakes decision making such as medical image segmentation. However, most existing methods reduce uncertainty to a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 An Sui , Yuzhu Li , Gunter Schumann , Fuping Wu , Xiahai Zhuang

In health related machine learning applications, the training data often corresponds to a non-representative sample from the target populations where the learners will be deployed. In anticausal prediction tasks, selection biases often make…

Machine Learning · Statistics 2020-11-10 Elias Chaibub Neto , Phil Snyder , Solveig K Sieberts , Larsson Omberg

Interpretability is highly desired for deep neural network-based classifiers, especially when addressing high-stake decisions in medical imaging. Commonly used post-hoc interpretability methods have the limitation that they can produce…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Sourya Sengupta , Mark A. Anastasio

Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Yoni Schirris , Eric Marcus , Jonas Teuwen , Hugo Horlings , Efstratios Gavves

Recently, face recognition systems have demonstrated remarkable performances and thus gained a vital role in our daily life. They already surpass human face verification accountability in many scenarios. However, they lack explanations for…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Martin Knoche , Torben Teepe , Stefan Hörmann , Gerhard Rigoll

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

This paper presents a comprehensive approach for model-based diagnosis which includes proposals for characterizing and computing preferred diagnoses, assuming that the system description is augmented with a system structure (a directed…

Artificial Intelligence · Computer Science 2014-11-17 A. Darwiche

Uncertainty estimation has been widely studied in medical image segmentation as a tool to provide reliability, particularly in deep learning approaches. However, previous methods generally lack effective supervision in uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuzhu Li , An Sui , Fuping Wu , Xiahai Zhuang

Cognitive diagnosis models have been popularly used in fields such as education, psychology, and social sciences. While parametric likelihood estimation is a prevailing method for fitting cognitive diagnosis models, nonparametric…

Statistics Theory · Mathematics 2025-10-01 Chengyu Cui , Yanlong Liu , Gongjun Xu

Reliable and interpretable decision-making is essential in medical imaging, where diagnostic outcomes directly influence patient care. Despite advances in deep learning, most medical AI systems operate as opaque black boxes, providing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Pirzada Suhail , Aditya Anand , Amit Sethi

Machine Learning has been applied to pathology images in research and clinical practice with promising outcomes. However, standard ML models often lack the rigorous evaluation required for clinical decisions. Machine learning techniques for…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Syed Ashar Javed , Dinkar Juyal , Zahil Shanis , Shreya Chakraborty , Harsha Pokkalla , Aaditya Prakash

In medical imaging, segmentation models have known a significant improvement in the past decade and are now used daily in clinical practice. However, similar to classification models, segmentation models are affected by adversarial attacks.…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Othmane Laousy , Alexandre Araujo , Guillaume Chassagnon , Nikos Paragios , Marie-Pierre Revel , Maria Vakalopoulou

Energy systems optimisation models are a leading tool for informing decisions in the energy transition. However, these models often remain opaque, and results are frequently presented without a clear discussion of their epistemic…

Medical images are generally labeled by multiple experts before the final ground-truth labels are determined. Consensus or disagreement among experts regarding individual images reflects the gradeability and difficulty levels of the image.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Shuang Yu , Hong-Yu Zhou , Kai Ma , Cheng Bian , Chunyan Chu , Hanruo Liu , Yefeng Zheng

Diagnostic imaging studies are an increasingly important component of the workup and management of acutely presenting patients. However, ordering appropriate imaging studies according to evidence-based medical guidelines is a challenging…

Machine Learning · Computer Science 2025-08-06 Michael S. Yao , Allison Chae , Charles E. Kahn , Walter R. Witschey , James C. Gee , Hersh Sagreiya , Osbert Bastani

Conformal prediction is a statistically rigorous method for quantifying uncertainty in models by having them output sets of predictions, with larger sets indicating more uncertainty. However, prediction sets are not inherently actionable;…

Machine Learning · Computer Science 2025-02-17 Jesse C. Cresswell , Bhargava Kumar , Yi Sui , Mouloud Belbahri

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu