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Related papers: Joint Models for Cause-of-Death Mortality in Multi…

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A linear mixed-effects (LME) model is proposed for modelling and forecasting single and multi-population age-specific death rates (ASDRs). The innovative approach that we take in this study treats age, the interaction between gender and…

Applications · Statistics 2025-11-18 Reza Dastranj , Martin Kolar

Multimorbidity, the co-occurrence of two or more chronic diseases such as diabetes, obesity or cardiovascular diseases in one patient, is a frequent phenomenon. To make care more efficient, it is of relevance to understand how different…

Medical Physics · Physics 2019-08-05 Nils Haug , Stefan Thurner , Alexandra Kautzky-Willer , Michael Gyimesi , Peter Klimek

When drawing causal inferences about the effects of multiple treatments on clustered survival outcomes using observational data, we need to address implications of the multilevel data structure, multiple treatments, censoring and unmeasured…

Methodology · Statistics 2022-02-18 Liangyuan Hu , Jiayi Ji , Ronald D. Ennis , Joseph W. Hogan

In the evolving world, we require more additionally the young era to flourish and evolve into developed land. Most of the population all around the world are unaware of the complications involved in the routine they follow while they are…

Machine Learning · Computer Science 2023-12-08 S. Nandini , Sanjjushri Varshini R

Cause-of-death data is fundamental for understanding population health trends and inequalities as well as designing and evaluating public health interventions. A significant proportion of global deaths, particularly in low- and…

Applications · Statistics 2025-02-04 Yu Zhu , Zehang Richard Li

Child mortality is an important population health indicator. However, many countries lack high-quality vital registration to measure child mortality rates precisely and reliably over time. Research endeavors such as those by the United…

Applications · Statistics 2026-01-29 Katherine R Paulson , Taylor Okonek , Jon Wakefield

Research on Poisson regression analysis for dependent data has been developed rapidly in the last decade. One of difficult problems in a multivariate case is how to construct a cross-correlation structure and at the meantime make sure that…

Methodology · Statistics 2017-10-05 A'yunin Sofro , Jian Qing Shi , Chunzheng Cao

The use of artificial intelligence in clinical care to improve decision support systems is increasing. This is not surprising since, by its very nature, the practice of medicine consists of making decisions based on observations from…

Quantitative Methods · Quantitative Biology 2019-05-03 Isaac Mativo , Yelena Yesha , Michael Grasso , Tim Oates , Qian Zhu

As cancer patient survival improves, late effects from treatment are becoming the next clinical challenge. Chemotherapy and radiotherapy, for example, potentially increase the risk of both morbidity and mortality from second malignancies…

Estimating causal effects in quasi-experiments with spatio-temporal panel data often requires adjusting for unmeasured confounding that varies across space and time. Gaussian Processes (GPs) offer a flexible, nonparametric modeling approach…

Methodology · Statistics 2025-07-08 Sofia L. Vega , Rachel C. Nethery

Ecological Momentary Assessment provides real-time data on suicidal thoughts and behaviors, but predicting suicide attempts remains challenging due to their rarity and patient heterogeneity. We show that single models fit to all patients…

Machine Learning · Statistics 2025-11-25 Genesis Hang , Annie Chen , Hope Neveux , Matthew K. Nock , Yaniv Yacoby

Joinpoint regression is used to determine the number of segments needed to adequately explain the relationship between two variables. This methodology can be widely applied to real problems, but we focus on epidemiological data, the main…

Applications · Statistics 2011-12-08 Miguel A. Martinez-Beneito , Gonzalo García-Donato , Diego Salmerón

Age-specific mortality rates are often disaggregated by different attributes, such as sex, state, ethnic group and socioeconomic status. In making social policies and pricing annuity at national and subnational levels, it is important not…

Applications · Statistics 2017-05-24 Han Lin Shang , Steven Haberman

The analysis of complex longitudinal data such as COVID-19 deaths is challenging due to several inherent features: (i) Similarly-shaped profiles with different decay patterns; (ii) Unexplained variation among repeated measurements within…

In the aftermath of the COVID-19 pandemic, empirical data have revealed that large-scale health crises not only cause immediate disruptions in mortality dynamics but also have persistent effects that may last for several years. Existing…

Applications · Statistics 2026-03-26 Yanxin Liu , Kenneth Q. Zhou

When modeling sub-national mortality rates, it is important to incorporate any possible correlation among sub-populations to improve forecast accuracy. Moreover, forecasts at the sub-national level should aggregate consistently across the…

Applications · Statistics 2020-11-17 Han Lin Shang , Yang Yang

This study introduces a novel generalized additive mixed model (GAMM) for mortality modelling, utilizing the mortality covariate $k_t$ as proposed by Dastranj-Kolar. Our findings indicate that the GAMM effectively addresses this…

Applications · Statistics 2025-11-18 Reza Dastranj , Martin Kolar

We make use of Kronecker structure for scaling Gaussian Process models to large-scale, heterogeneous, clinical data sets. Repeated measures, commonly performed in clinical research, facilitate computational acceleration for nonlinear…

Methodology · Statistics 2024-08-29 Owen Thomas , Leiv Rønneberg

In this paper, we introduce the use of a personalized Gaussian Process model (pGP) to predict the key metrics of Alzheimer's Disease progression (MMSE, ADAS-Cog13, CDRSB and CS) based on each patient's previous visits. We start by learning…

Machine Learning · Computer Science 2018-05-07 Kelly Peterson , Ognjen Rudovic , Ricardo Guerrero , Rosalind W. Picard

Joint modelling of longitudinal and time-to-event data has received much attention recently. Increasingly, extensions to standard joint modelling approaches are being proposed to handle complex data structures commonly encountered in…

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