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We present a general theory for predicting the interaction potentials between DNA-coated colloids, and more broadly, any particles that interact via valence-limited ligand-receptor binding. Our theory correctly incorporates the…

Soft Condensed Matter · Physics 2015-06-05 Patrick Varilly , Stefano Angioletti-Uberti , Bortolo M. Mognetti , Daan Frenkel

By exploiting the exquisite selectivity of DNA hybridization, DNA-Coated Colloids (DNACCs) can be made to self-assemble in a wide variety of structures. The beauty of this system stems largely from its exceptional versatility and from the…

Soft Condensed Matter · Physics 2016-01-29 Stefano Angioletti-Uberti , Bortolo M. Mognetti , Daan Frenkel

In recent years significant attention has been attracted to proposals which utilize DNA for nanotechnological applications. Potential applications of these ideas range from the programmable self-assembly of colloidal crystals, to biosensors…

Soft Condensed Matter · Physics 2008-05-02 Nicholas A. Licata

DNA-coated particles are promising as building blocks for functional and finite-sized assemblies because they can be programmed with orthogonal interactions owing to the sequence-specific hybridization of DNA strands. To fully exploit this…

Soft Condensed Matter · Physics 2026-04-17 T. C. M. Stevens , A. van der Sluis , I. K. Voets , P. G. Moerman

We present a quantitative, multi-scale coarse-grained model of DNA coated colloids. The parameters of this model are transferable and are solely based on experimental data. As a test case, we focus on nano-sized colloids carrying…

Just like atoms combine into molecules, colloids can self-organize into predetermined structures according to a set of design principles. Controlling valence -- the number of inter-particle bonds -- is a prerequisite for the assembly of…

Soft Condensed Matter · Physics 2022-01-05 Angus McMullen , Sascha Hilgenfeldt , Jasna Brujic

The possibility of prescribing local interactions between nano- and microscopic components that direct them to assemble in a predictable fashion is a central goal of nanotechnology research. In this article we advance a new paradigm in…

DNA-coated colloids can self-assemble into an incredible diversity of crystal structures, but applications of this technology are limited by poor understanding and control over the dynamical crystallization pathways. To address this…

Soft Condensed Matter · Physics 2021-06-01 Alexander Hensley , William M. Jacobs , W. Benjamin Rogers

We construct a theoretical model for the dynamics of a microscale colloidal particle, modeled as an interval, moving horizontally on a DNA-coated surface, modelled as a line coated with springs that can stick to the interval. Averaging over…

Soft Condensed Matter · Physics 2018-09-28 James P. Lee-Thorp , Miranda Holmes-Cerfon

Developing construction methods of materials tailored for given applications with absolute control over building block placement poses an immense challenge. DNA-coated colloids offer the possibility of realising programmable self-assembly,…

Soft Condensed Matter · Physics 2020-05-22 Xiuyang Xia , Hao Hu , Massimo Pica Ciamarra , Ran Ni

Self-assembly is traditionally described as the process through which an initially disordered system relaxes towards an equilibrium ordered phase only driven by local interactions between its building blocks. However, This definition is too…

Soft Condensed Matter · Physics 2015-06-15 Lorenzo Di Michele , Francesco Varrato , Jurij Kotar , Simon H. Nathan , Giuseppe Foffi , Erika Eiser

The interaction between light and matter can be controlled efficiently by structuring materials at a length scale shorter than the wavelength of interest. With the goal to build optical devices that operate at the nanoscale, plasmonics has…

Optics · Physics 2021-05-06 Na Liu , Tim Liedl

DNA-mediated multivalent interactions between colloidal particles have been extensively applied for their ability to program bulk phase behaviour and dynamic processes. Exploiting the competition between different types of DNA-DNA bonds,…

DNA-coated colloids are a popular model system for self-assembly through tunable interactions. The DNA-encoded linkages between particles theoretically allow for very high specificity, but generally no directionality or long-range…

Soft Condensed Matter · Physics 2010-08-24 Simon H. Tindemans , Bela M. Mulder

We propose a new strategy to improve the self-assembly properties of DNA-functionalised colloids. The problem that we address is that DNA-functionalised colloids typically crystallize in a narrow temperature window, if at all. The…

Soft Condensed Matter · Physics 2013-01-22 B. M. Mognetti , M. E. Leunissen , D. Frenkel

We present a coarse-grained model of DNA-functionalized colloids that is computationally tractable. Importantly, the model parameters are solely based on experimental data. Using this highly simplified model, we can predict the phase…

Nearly thirty years after its inception, the field of DNA-programmed colloidal self-assembly has begun to realize its initial promise. In this review, we summarize recent developments in designing effective interactions and understanding…

Soft Condensed Matter · Physics 2025-05-08 William M. Jacobs , W. Benjamin Rogers

In equilibrium self-assembly, microscopic building blocks spontaneously self-organize into stable structures as dictated by their interaction potentials, which limits the accessible structural features to those that correspond to global…

Soft Condensed Matter · Physics 2026-04-17 Pepijn G. Moerman , Chenghung Chou , Thomas E. Videbæk , W. Benjamin Rogers , Rebecca Schulman

We demonstrate the realization of (laterally) optically bounded colloidal structures on a liquid-liquid interface of an emulsion droplet. We use DNA tethers to graft the particles to the droplet surface, effectively confining them to a…

Soft Condensed Matter · Physics 2017-03-27 Alessio Caciagli , Darshana Joshi , Jurij Kotar , Erika Eiser

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume
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