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When modelling metapopulation dynamics, the influence of a single patch on the metapopulation depends on the number of individuals in the patch. Since there is usually no obvious natural upper limit on the number of individuals in a patch,…

Probability · Mathematics 2012-01-27 A. D. Barbour , M. J. Luczak

In stochastic modeling of infectious diseases, it has been established that variations in infectivity affect the probability of a major outbreak, but not the shape of the curves during a major outbreak, which is predicted by deterministic…

Physics and Society · Physics 2022-12-12 F Rousse , M Carlsson , M Ogren , B Kalischer Wellander

This paper examines an epidemic patch model with mass-action transmission mechanism and asymmetric connectivity matrix. Results on the global dynamics of solutions and the spatial structures of endemic solutions are obtained. In particular,…

Classical Analysis and ODEs · Mathematics 2023-11-14 Rachidi Salako , Yixiang Wu

Stochastic infection processes are continuous-time Markov chains on graphs that assign each vertex one of multiple states, such as susceptible, infected, or recovered. Depending on the model, vertices change their state based on random…

Probability · Mathematics 2026-05-20 Nicolas Klodt , Martin S. Krejca

We consider a general class of epidemic models obtained by applying a random time change to a collection of Poisson processes and we show the large deviation principle for such models. We generalize to a more general situation the approach…

Probability · Mathematics 2020-03-10 Etienne Pardoux , Brice Samegni-Kepgnou

In this survey paper, we review the recent advances in individual based non--Markovian epidemic models. They include epidemic models with a constant infectivity rate, varying infectivity rate or infection-age dependent infectivity,…

Probability · Mathematics 2022-09-26 Raphael Forien , Guodong Pang , Etienne Pardoux

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

We study a stochastic spatial epidemic model where the $N$ individuals carry two features: a position and an infection state, interact and move in $\R^d$. In this Markovian model, the evolution of the infection states are described with the…

Probability · Mathematics 2021-11-05 Yen V. Vuong , Maxime Hauray , Etienne Pardoux

Changes in human behavior are increasingly recognized as a major determinant of epidemic dynamics. Although collective activity can be modified through imposed measures to control epidemic progression, spontaneous changes can also arise as…

Populations and Evolution · Quantitative Biology 2021-05-25 Susanna Manrubia , Damián H. Zanette

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

A simple, but ``classical``, stochastic model for epidemic spread in a finite, but large, population is studied. The progress of the epidemic can be divided into three different phases that requires different tools to analyse. Initially the…

Populations and Evolution · Quantitative Biology 2018-05-29 Åke Svensson

We investigate the SIR epidemic on a dynamic inhomogeneous Erd\H{o}s-R\'enyi random graph, in which vertices are of one of $k$ types and in which edges appear and disappear independently of each other. We establish a functional law of large…

Probability · Mathematics 2024-04-22 Yuanfei Huang , Adrian Röllin

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

Epidemic spread in single-host systems strongly depends on the population's contact network. However, little is known regarding the spread of epidemics across networks representing populations of multiple hosts. We explored cross-species…

Populations and Evolution · Quantitative Biology 2017-12-06 Shai Pilosof , Gili Greenbaum , Boris R. Krasnov , Yuval R. Zelnik

We analyze a Markovian SIR epidemic model where individuals either recover naturally or are diagnosed, leading to isolation and potential contact tracing. Our focus is on digital contact tracing via a tracing app, considering both its…

Probability · Mathematics 2026-01-14 Tom Britton , Dongni Zhang

Recent years have seen a large amount of interest in epidemics on networks as a way of representing the complex structure of contacts capable of spreading infections through the modern human population. The configuration model is a popular…

Populations and Evolution · Quantitative Biology 2017-01-23 Frank Ball , Thomas House

The propagation of infectious diseases and its impact on individuals play a major role in disease dynamics, and it is important to incorporate population heterogeneity into efforts to study diseases. As a simplistic but illustrative…

Populations and Evolution · Quantitative Biology 2019-07-24 Juan G. Calvo , Alberto Hernández , Mason A. Porter , Fabio Sanchez

We consider a stochastic SIR (susceptible $\to$ infective $\to$ recovered) epidemic defined on a configuration model random graph, in which infective individuals can infect only their neighbours in the graph during an infectious period…

Probability · Mathematics 2018-12-10 Frank Ball

We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals…

Populations and Evolution · Quantitative Biology 2012-02-14 Artem S. Novozhilov

Density dependent Markov population processes with countably many types can often be well approximated over finite time intervals by the solution of the differential equations that describe their average drift, provided that the total…

Probability · Mathematics 2014-06-05 A. D. Barbour , Malwina Luczak