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Typical computational techniques for vascular biomechanics represent the blood vessel wall via either a membrane, a shell, or a 3D solid element. Each of these formulations has its trade offs concerning accuracy, ease of implementation, and…

The discrete fracture model (DFM) has been widely used in the simulation of fluid flow in fractured porous media. Traditional DFM uses the so-called hybrid-dimensional approach to treat fractures explicitly as low-dimensional entries (e.g.…

Numerical Analysis · Mathematics 2021-02-01 Ziyao Xu , Yang Yang

Dynamic MRI may capture temporal anatomical changes in soft tissue organs with high contrast but the obtained sequences usually suffer from limited volume coverage which makes the high resolution reconstruction of organ shape trajectories a…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Karim Makki , Amine Bohi , Augustin . C Ogier , Marc Emmanuel Bellemare

The task of shape abstraction with semantic part consistency is challenging due to the complex geometries of natural objects. Recent methods learn to represent an object shape using a set of simple primitives to fit the target.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Di Liu , Long Zhao , Qilong Zhangli , Yunhe Gao , Ting Liu , Dimitris N. Metaxas

We introduce DMTet, a deep 3D conditional generative model that can synthesize high-resolution 3D shapes using simple user guides such as coarse voxels. It marries the merits of implicit and explicit 3D representations by leveraging a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Tianchang Shen , Jun Gao , Kangxue Yin , Ming-Yu Liu , Sanja Fidler

In this paper, we propose a novel one-dimensional (1D) discrete differential geometry (DDG)-based numerical method for geometrically nonlinear mechanics analysis (e.g., buckling and snapping) of axisymmetric shell structures. Our numerical…

Soft Condensed Matter · Physics 2024-10-01 Weicheng Huang , Tianzhen Liu , Zhaowei Liu , Peifei Xu , Mingchao Liu , Yuzhen Chen , K. Jimmy Hsia

We consider a discrete-continuum model of a biomembrane with embedded particles. While the membrane is represented by a continuous surface, embedded particles are described by rigid discrete objects which are free to move and rotate in…

Analysis of PDEs · Mathematics 2021-04-29 Tobias Kies , Carsten Gräser

Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have…

Tissues and Organs · Quantitative Biology 2017-07-27 Richard J. McMurtrey

Molecular dynamics (MD) has long been the de facto choice for simulating complex atomistic systems from first principles. Recently deep learning models become a popular way to accelerate MD. Notwithstanding, existing models depend on…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Fang Wu , Stan Z. Li

The Dynamical Graph Grammar (DGG) formalism can describe complex system dynamics with graphs that are mapped into a master equation. An exact stochastic simulation algorithm may be used, but it is slow for large systems. To overcome this…

Quantitative Methods · Quantitative Biology 2024-07-16 Eric Medwedeff , Eric Mjolsness

The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

Biological Physics · Physics 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

This paper presents a novel soft robotic system for a deformable mannequin that can be employed to physically realize the 3D geometry of different human bodies. The soft membrane on a mannequin is deformed by inflating several curved…

Robotics · Computer Science 2022-05-24 Yingjun Tian , Guoxin Fang , Justas Petrulis , Andrew Weightman , Charlie C. L. Wang

Cell plasma membranes display a dramatically rich structural complexity characterized by functional sub-wavelength domains with specific lipid and protein composition. Under favorable experimental conditions, patterned morphologies can also…

Soft Condensed Matter · Physics 2018-10-02 Nicolas Destainville , Manoel Manghi , Julie Cornet

This paper introduces a novel framework called DTNet for 3D mesh reconstruction and generation via Disentangled Topology. Beyond previous works, we learn a topology-aware neural template specific to each input then deform the template to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-13 Ka-Hei Hui , Ruihui Li , Jingyu Hu , Chi-Wing Fu

Triangle meshes remain the most popular data representation for surface geometry. This ubiquitous representation is essentially a hybrid one that decouples continuous vertex locations from the discrete topological triangulation.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-23 Marie-Julie Rakotosaona , Noam Aigerman , Niloy Mitra , Maks Ovsjanikov , Paul Guerrero

Recent developments in lipid membrane models for simulations are reviewed. To reduce computational costs, various coarse-grained molecular models have been proposed. Among them, implicit solvent (solvent-free) molecular models are…

Soft Condensed Matter · Physics 2015-05-13 Hiroshi Noguchi

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

The understanding of morphogenesis in living organisms has been renewed by tremendous progressin experimental techniques that provide access to cell-scale, quantitative information both on theshapes of cells within tissues and on the genes…

Biological Physics · Physics 2015-09-30 Sham Tlili , Cyprien Gay , Francois Graner , Philippe Marcq , François Molino , Pierre Saramito

Although cell shape can reflect the mechanical and biochemical properties of the cell and its environment, quantification of 3D cell shapes within 3D tissues remains difficult, typically requiring digital reconstruction from a stack of 2D…

Quantitative Methods · Quantitative Biology 2019-03-06 Tristan A. Sharp , Matthias Merkel , M. Lisa Manning , Andrea J. Liu

3D geometric contents are becoming increasingly popular. In this paper, we study the problem of analyzing deforming 3D meshes using deep neural networks. Deforming 3D meshes are flexible to represent 3D animation sequences as well as…

Graphics · Computer Science 2018-03-30 Qingyang Tan , Lin Gao , Yu-Kun Lai , Shihong Xia