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Model interpretability has become important to engenders appropriate user trust by providing the insight into the model prediction. However, most of the existing machine learning methods provide no interpretability for depression…

Information Retrieval · Computer Science 2021-04-29 Hamad Zogan , Imran Razzak , Xianzhi Wang , Shoaib Jameel , Guandong Xu

We propose a simple approach for weighting self-connecting edges in a Graph Convolutional Network (GCN) and show its impact on depression detection from transcribed clinical interviews. To this end, we use a GCN for modeling non-consecutive…

Computation and Language · Computer Science 2024-03-12 Sergio Burdisso , Esaú Villatoro-Tello , Srikanth Madikeri , Petr Motlicek

Depression is a widespread mental health issue affecting diverse age groups, with notable prevalence among college students and the elderly. However, existing datasets and detection methods primarily focus on young adults, neglecting the…

Recent studies in neuroscience highlight the significant potential of brain connectivity networks, which are commonly constructed from functional magnetic resonance imaging (fMRI) data for brain disorder diagnosis. Traditional brain…

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

Depression, as a typical mental disorder, has become a prevalent issue significantly impacting public health. However, the prevention and treatment of depression still face multiple challenges, including complex diagnostic procedures,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yu Luo , Nan Huang , Sophie Yu , Hendry Xu , Jerry Wang , Colin Wang , Zhichao Liu , Chen Zeng

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Major Depressive Disorder (MDD) is a clinically heterogeneous syndrome with diverse etiological pathways. Traditional Epigenome-Wide Association Studies (EWAS) have successfully identified risk loci based on differential methylation…

Computational Engineering, Finance, and Science · Computer Science 2026-01-27 Mingyan Liu , Min Huang

Tremendous recent literature show that associations between different brain regions, i.e., brain connectivity, provide early symptoms of neurological disorders. Despite significant efforts made for graph neural network (GNN) techniques,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Xin Ma , Guorong Wu , Seong Jae Hwang , Won Hwa Kim

Identifying functional connectivity biomarkers of major depressive disorder (MDD) patients is essential to advance understanding of the disorder mechanisms and early intervention. However, due to the small sample size and the high dimension…

Machine Learning · Computer Science 2023-01-09 Shuai Liu , Xiao Guo , Shun Qi , Huaning Wang , Xiangyu Chang

Large-scale collaborative analysis of brain imaging data, in psychiatry and neu-rology, offers a new source of statistical power to discover features that boost ac-curacy in disease classification, differential diagnosis, and outcome…

Large Language Models (LLMs) have demonstrated remarkable success across diverse fields, establishing a powerful paradigm for complex information processing. This has inspired the integration of speech into LLM frameworks, often by…

Audio and Speech Processing · Electrical Eng. & Systems 2025-12-30 Xiangyu Zhang , Fuming Fang , Peng Gao , Bin Qin , Beena Ahmed , Julien Epps

Compressed sensing MRI is a classic inverse problem in the field of computational imaging, accelerating the MR imaging by measuring less k-space data. The deep neural network models provide the stronger representation ability and faster…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Zhiwen Fan , Liyan Sun , Xinghao Ding , Yue Huang , Congbo Cai , John Paisley

It is essential to understand the complex structure of the human brain to develop new treatment approaches for neurodegenerative disorders (NDDs). This review paper comprehensively discusses the challenges associated with modelling the…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Depression is a common mental health disorder that can cause consequential symptoms with continuously depressed mood that leads to emotional distress. One category of depression is Concealed Depression, where patients intentionally or…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Xiaohui Chen , Tie Luo

The people with Major Depressive Disorder (MDD) exhibit the symptoms of tonal variations in their speech compared to the healthy counterparts. However, these tonal variations not only confine to the state of MDD but also on the language,…

Computation and Language · Computer Science 2024-09-24 Sona Binu , Jismi Jose , Fathima Shimna K , Alino Luke Hans , Reni K. Cherian , Starlet Ben Alex , Priyanka Srivastava , Chiranjeevi Yarra

Multimodal depression classification has gained immense popularity over the recent years. We develop a multimodal depression classification system using articulatory coordination features extracted from vocal tract variables and text…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-15 Nadee Seneviratne , Carol Espy-Wilson

We propose a novel explainable machine learning (ML) model that identifies depression from speech, by modeling the temporal dependencies across utterances and utilizing the spectrotemporal information at the vowel level. Our method first…

Sound · Computer Science 2022-10-28 Kexin Feng , Theodora Chaspari

Accurate identification of late-life depression (LLD) using structural brain MRI is essential for monitoring disease progression and facilitating timely intervention. However, existing learning-based approaches for LLD detection are often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Yuzhen Gao , Qianqian Wang , Yongheng Sun , Cui Wang , Yongquan Liang , Mingxia Liu
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