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Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activities, and can be very useful in the studies of brain…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Chao Cao , Tong Chen , Minheng Chen , Yan Zhuang , Tianming Liu , Dajiang Zhu

We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently…

Machine Learning · Computer Science 2020-04-27 Chun-Ren Phang , Chee-Ming Ting , Fuad Noman , Hernando Ombao

Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Weizheng Yan , Han Zhang , Jing Sui , Dinggang Shen

Timely and objective screening of major depressive disorder (MDD) is vital, yet diagnosis still relies on subjective scales. Electroencephalography (EEG) provides a low-cost biomarker, but existing deep models treat spectra as static…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Jingru Qiu , Jiale Liang , Xuanhan Fan , Mingda Zhang , Zhenli He

Depression is ranked as the largest contributor to global disability and is also a major reason for suicide. Still, many individuals suffering from forms of depression are not treated for various reasons. Previous studies have shown that…

Computation and Language · Computer Science 2024-10-30 Marcel Trotzek , Sven Koitka , Christoph M. Friedrich

Functional connectivity network (FCN) data from functional magnetic resonance imaging (fMRI) is increasingly used for the diagnoses of brain disorders. However, state-of-the-art studies used to build the FCN using a single brain…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Mianxin Liu , Han Zhang , Feng Shi , Dinggang Shen

Psychiatric disorders involve complex neural activity changes, with functional magnetic resonance imaging (fMRI) data serving as key diagnostic evidence. However, data scarcity and the diverse nature of fMRI information pose significant…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Mujie Liu , Mengchu Zhu , Qichao Dong , Ting Dang , Jiangang Ma , Jing Ren , Feng Xia

In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

Neurons and Cognition · Quantitative Biology 2019-03-28 Milena Cukic Radenkovic

Mental disorders like major depressive disorder can be seen as complex dynamical systems. In this study we investigate the dynamic behaviour of individuals to see whether or not we can expect a transition to another mood state. We introduce…

Physics and Society · Physics 2019-03-27 Jolanda J Kossakowski , Marijke C M Gordijn , Harriette Riese , Lourens J Waldorp

In this work we propose a machine learning model for depression detection from transcribed clinical interviews. Depression is a mental disorder that impacts not only the subject's mood but also the use of language. To this end we use a…

Computation and Language · Computer Science 2020-06-16 D. Xezonaki , G. Paraskevopoulos , A. Potamianos , S. Narayanan

Cardiovascular diseases (CVD) and depression exhibit significant comorbidity, which is highly predictive of poor clinical outcomes. Yet, the underlying biological pathways remain challenging to decipher, presumably due to the non-linear…

Diagnosing Major Depressive Disorder (MDD) from functional magnetic resonance imaging (fMRI) using functional connectivity (FC) analysis requires large amounts of labeled data that are scarce in clinical settings. Existing augmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Depression is one of the leading causes of disability worldwide, posing a severe burden on individuals, healthcare systems, and society at large. Recent advancements in Large Language Models (LLMs) have shown promise in addressing mental…

Computation and Language · Computer Science 2025-02-11 Shiyu Teng , Jiaqing Liu , Rahul Kumar Jain , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-wei Chen

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by complex physiological processes. Previous research has predominantly focused on static cerebral interactions, often neglecting the brain's dynamic nature and…

Machine Learning · Computer Science 2024-09-11 Peng Wang , Xin Wen , Ruochen Cao , Chengxin Gao , Yanrong Hao , Rui Cao

Obsessive-compulsive disorder (OCD) is a common psychiatric disorder with a lifetime prevalence of 2-3 percent. Recently, brain activity in the resting state is gathering attention as a new means of exploring altered functional connectivity…

Background: Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) has proven to be a powerful technique to help subjects to gauge and enhance emotional control. Traditionally, rtfMRI-nf has focused on emotional…

Dynamic functional connectivity (dFC) derived from resting-state functional magnetic resonance imaging (fMRI) has been extensively utilized in brain science research. The sliding window correlation (SWC) method is a widely used approach for…

Neurons and Cognition · Quantitative Biology 2026-03-27 Jinlong Hu , Jiatong Huang , Zijian Cai

Depression is a growing concern gaining attention in both public discourse and AI research. While deep neural networks (DNNs) have been used for recognition, they still lack real-world effectiveness. Large language models (LLMs) show strong…

Human-Computer Interaction · Computer Science 2025-08-27 Yupei Li , Shuaijie Shao , Manuel Milling , Björn W. Schuller

Sleep stage classification is essential for sleep assessment and disease diagnosis. Although previous attempts to classify sleep stages have achieved high classification performance, several challenges remain open: 1) How to effectively…

Signal Processing · Electrical Eng. & Systems 2021-09-07 Ziyu Jia , Youfang Lin , Jing Wang , Xiaojun Ning , Yuanlai He , Ronghao Zhou , Yuhan Zhou , Li-wei H. Lehman

This paper presents our solution to the Multimodal Personality-aware Depression Detection (MPDD) challenge at ACM MM 2025. We propose a multimodal depression detection model in the Elderly that incorporates personality characteristics. We…

Sound · Computer Science 2025-10-10 Honghong Wang , Jing Deng , Rong Zheng