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The journey of reducing noise from distant supervision (DS) generated training data has been started since the DS was first introduced into the relation extraction (RE) task. For the past decade, researchers apply the multi-instance…

Computation and Language · Computer Science 2021-06-22 Tao Chen , Haizhou Shi , Siliang Tang , Zhigang Chen , Fei Wu , Yueting Zhuang

We consider a weakly supervised learning scenario where the supervision signal is generated by a transition function $\sigma$ of labels associated with multiple input instances. We formulate this problem as \emph{multi-instance Partial…

Machine Learning · Computer Science 2024-07-16 Kaifu Wang , Efthymia Tsamoura , Dan Roth

The paper proposes a novel multi-class Multiple-Instance Learning (MIL) problem called Learning from Majority Label (LML). In LML, the majority class of instances in a bag is assigned as the bag-level label. The goal of LML is to train a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Shiku Kaito , Shinnosuke Matsuo , Daiki Suehiro , Ryoma Bise

In many real-world tasks, particularly those involving data objects with complicated semantics such as images and texts, one object can be represented by multiple instances and simultaneously be associated with multiple labels. Such tasks…

Machine Learning · Computer Science 2020-07-07 Sheng-Jun Huang , Zhi-Hua Zhou

Multiple Instance Learning (MIL) has been widely used in weakly supervised whole slide image (WSI) classification. Typical MIL methods include a feature embedding part, which embeds the instances into features via a pre-trained feature…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Peijie Qiu , Pan Xiao , Wenhui Zhu , Yalin Wang , Aristeidis Sotiras

Recent advances in attention-based multiple instance learning (MIL) have improved our insights into the tissue regions that models rely on to make predictions in digital pathology. However, the interpretability of these approaches is still…

Quantitative Methods · Quantitative Biology 2023-09-11 Willem Bonnaffé , CRUK ICGC Prostate Group , Freddie Hamdy , Yang Hu , Ian Mills , Jens Rittscher , Clare Verrill , Dan J. Woodcock

Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

Although multiple instance learning (MIL) methods are widely used for automatic tumor detection on whole slide images (WSI), they suffer from the extreme class imbalance within the small tumor WSIs. This occurs when the tumor comprises only…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Shuo Niu , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

In computational pathology, whole-slide image (WSI) classification presents a formidable challenge due to its gigapixel resolution and limited fine-grained annotations. Multiple-instance learning (MIL) offers a weakly supervised solution,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Renao Yan , Qiehe Sun , Cheng Jin , Yiqing Liu , Yonghong He , Tian Guan , Hao Chen

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Annotating multi-class instances is a crucial task in the field of machine learning. Unfortunately, identifying the correct class label from a long sequence of candidate labels is time-consuming and laborious. To alleviate this problem, we…

Machine Learning · Computer Science 2025-12-05 Meng Wei , Zhongnian Li , Yong Zhou , Qiaoyu Guo , Xinzheng Xu

With the development of computational pathology, deep learning methods for Gleason grading through whole slide images (WSIs) have excellent prospects. Since the size of WSIs is extremely large, the image label usually contains only…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Hao Bian , Zhuchen Shao , Yang Chen , Yifeng Wang , Haoqian Wang , Jian Zhang , Yongbing Zhang

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

Artificial Intelligence · Computer Science 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

The visual examination of tissue biopsy sections is fundamental for cancer diagnosis, with pathologists analyzing sections at multiple magnifications to discern tumor cells and their subtypes. However, existing attention-based multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Olga Fourkioti , Matt De Vries , Chen Jin , Daniel C. Alexander , Chris Bakal

Multiple instance data are sets or multi-sets of unordered elements. Using metrics or distances for sets, we propose an approach to several multiple instance learning tasks, such as clustering (unsupervised learning), classification…

Machine Learning · Computer Science 2017-03-28 Quang N. Tran , Ba-Ngu Vo , Dinh Phung , Ba-Tuong Vo , Thuong Nguyen

Uncertainty estimation (UE), as an effective means of quantifying predictive uncertainty, is crucial for safe and reliable decision-making, especially in high-risk scenarios. Existing UE schemes usually assume that there are…

Machine Learning · Computer Science 2024-05-10 Pei Liu , Luping Ji

Weakly-supervised temporal action localization aims to localize and recognize actions in untrimmed videos with only video-level category labels during training. Without instance-level annotations, most existing methods follow the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Huan Ren , Wenfei Yang , Tianzhu Zhang , Yongdong Zhang

Weakly supervised object detection (WSOD) is a challenging task that requires simultaneously learn object classifiers and estimate object locations under the supervision of image category labels. A major line of WSOD methods roots in…

Computer Vision and Pattern Recognition · Computer Science 2022-05-06 Shiwei Zhang , Wei Ke , Lin Yang

Weakly Supervised Video Anomaly Detection (WSVAD) is challenging because the binary anomaly label is only given on the video level, but the output requires snippet-level predictions. So, Multiple Instance Learning (MIL) is prevailing in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Hui Lv , Zhongqi Yue , Qianru Sun , Bin Luo , Zhen Cui , Hanwang Zhang

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Joohyung Lee , Heejeong Nam , Kwanhyung Lee , Sangchul Hahn