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We explore multiple instance verification, a problem setting in which a query instance is verified against a bag of target instances with heterogeneous, unknown relevancy. We show that naive adaptations of attention-based multiple instance…

Machine Learning · Computer Science 2025-09-18 Xin Xu , Eibe Frank , Geoffrey Holmes

In the application of Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) classification, attention mechanisms often focus on a subset of discriminative instances, which are closely linked to overfitting. To mitigate…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yunlong Zhang , Honglin Li , Yuxuan Sun , Sunyi Zheng , Chenglu Zhu , Lin Yang

Multi-instance learning attempts to learn from a training set consisting of labeled bags each containing many unlabeled instances. Previous studies typically treat the instances in the bags as independently and identically distributed.…

Machine Learning · Computer Science 2009-05-13 Zhi-Hua Zhou , Yu-Yin Sun , Yu-Feng Li

Multiple Instance Learning (MIL) has been widely applied to medical imaging diagnosis, where bag labels are known and instance labels inside bags are unknown. Traditional MIL assumes that instances in each bag are independent samples from a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Yunan Wu , Francisco M. Castro-Macías , Pablo Morales-Álvarez , Rafael Molina , Aggelos K. Katsaggelos

The dynamic environment of laboratories and clinics, with streams of data arriving on a daily basis, requires regular updates of trained machine learning models for consistent performance. Continual learning is supposed to help train models…

Machine Learning · Computer Science 2025-08-12 Zahra Ebrahimi , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

In multiple instance multiple label learning, each sample, a bag, consists of multiple instances. To alleviate labeling complexity, each sample is associated with a set of bag-level labels leaving instances within the bag unlabeled. This…

Machine Learning · Computer Science 2021-07-28 Tam Nguyen , Raviv Raich

In traditional multiple instance learning (MIL), both positive and negative bags are required to learn a prediction function. However, a high human cost is needed to know the label of each bag---positive or negative. Only positive bags…

Machine Learning · Computer Science 2016-03-17 Zhen Hu , Zhuyin Xue

Multiple instance learning (MIL) is a robust paradigm for whole-slide pathological image (WSI) analysis, processing gigapixel-resolution images with slide-level labels. As pioneering efforts, attention-based MIL (ABMIL) and its variants are…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Linghan Cai , Shenjin Huang , Ye Zhang , Jinpeng Lu , Yongbing Zhang

Multiple instance learning (MIL) is a key algorithm for classification of whole slide images (WSI). Histology WSIs can have billions of pixels, which create enormous computational and annotation challenges. Typically, such images are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Andriy Myronenko , Ziyue Xu , Dong Yang , Holger Roth , Daguang Xu

When applying multi-instance learning (MIL) to make predictions for bags of instances, the prediction accuracy of an instance often depends on not only the instance itself but also its context in the corresponding bag. From the viewpoint of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-25 Tiancheng Lin , Hongteng Xu , Canqian Yang , Yi Xu

In this paper, we propose a novel approach to tackle the multiple instance regression (MIR) problem. This problem arises when the data is a collection of bags, where each bag is made of multiple instances corresponding to the same unique…

Machine Learning · Statistics 2020-03-13 Thomas Uriot

Deep learning-based classification of rare anemia disorders is challenged by the lack of training data and instance-level annotations. Multiple Instance Learning (MIL) has shown to be an effective solution, yet it suffers from low accuracy…

Machine Learning · Computer Science 2022-07-06 Salome Kazeminia , Ario Sadafi , Asya Makhro , Anna Bogdanova , Shadi Albarqouni , Carsten Marr

We describe a novel weakly supervised deep learning framework that combines both the discriminative and generative models to learn meaningful representation in the multiple instance learning (MIL) setting. MIL is a weakly supervised…

Machine Learning · Computer Science 2018-07-09 Shabnam Ghaffarzadegan

Multiple instance learning (MIL) significantly reduced annotation costs via bag-level weak labels for large-scale images, such as histopathological whole slide images (WSIs). However, its adaptability to continual tasks with minimal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Byung Hyun Lee , Wongi Jeong , Woojae Han , Kyoungbun Lee , Se Young Chun

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

Multiple-instance learning (MIL) is a paradigm of machine learning that aims to classify a set (bag) of objects (instances), assigning labels only to the bags. This problem is often addressed by selecting an instance to represent each bag,…

Human-Computer Interaction · Computer Science 2021-12-22 Sonia Castelo , Moacir Ponti , Rosane Minghim

We introduce a graphical framework for multiple instance learning (MIL) based on Markov networks. This framework can be used to model the traditional MIL definition as well as more general MIL definitions. Different levels of ambiguity --…

Machine Learning · Computer Science 2013-09-27 Hossein Hajimirsadeghi , Jinling Li , Greg Mori , Mohammad Zaki , Tarek Sayed

The paper proposes a novel problem in multi-class Multiple-Instance Learning (MIL) called Learning from the Majority Label (LML). In LML, the majority class of instances in a bag is assigned as the bag's label. LML aims to classify…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Kaito Shiku , Shinnosuke Matsuo , Daiki Suehiro , Ryoma Bise

A new random forest based model for solving the Multiple Instance Learning (MIL) problem under small tabular data, called Soft Tree Ensemble MIL (STE-MIL), is proposed. A new type of soft decision trees is considered, which is similar to…

Machine Learning · Computer Science 2023-02-14 Andrei V. Konstantinov , Lev V. Utkin

Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2015-04-16 Deepak Pathak , Evan Shelhamer , Jonathan Long , Trevor Darrell