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In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple…

Optimization and Control · Mathematics 2021-12-17 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

In vaccine studies for infectious diseases such as human immunodeficiency virus (HIV), the frequency and type of contacts between study participants and infectious sources are among the most informative risk factors, but are often not…

Applications · Statistics 2012-08-27 Yang Yang , Peter Gilbert , Ira M. Longini, , M. Elizabeth Halloran

How to allocate vaccines over heterogeneous individuals is one of the important policy decisions in pandemic times. This paper develops a procedure to estimate an individualized vaccine allocation policy under limited supply, exploiting…

Econometrics · Economics 2021-10-25 Toru Kitagawa , Guanyi Wang

Understanding the network structure, and finding out the influential nodes is a challenging issue in the large networks. Identifying the most influential nodes in the network can be useful in many applications like immunization of nodes in…

Social and Information Networks · Computer Science 2017-01-10 Naveen Gupta , Anurag Singh , Hocine Cherifi

The non-backtracking matrix and its eigenvalues have many applications in network science and graph mining, such as node and edge centrality, community detection, length spectrum theory, graph distance, and epidemic and percolation…

Social and Information Networks · Computer Science 2020-02-28 Leo Torres , Kevin S. Chan , Hanghang Tong , Tina Eliassi-Rad

We formalize and study the problem of optimal allocation strategies for a (perfect) vaccine in the infinite-dimensional SIS model. The question may be viewed as a bi-objective minimization problem, where one tries to minimize simultaneously…

Probability · Mathematics 2021-08-27 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Network immunization is an automated task in the field of network analysis that involves protecting a network (modeled as a graph) from being infected by an undesired arbitrary diffusion. In this article, we consider the spread of harmful…

Social and Information Networks · Computer Science 2024-06-21 Elena-Simona Apostol , Özgur Coban , Ciprian-Octavian Truică

We study decentralized protection strategies against Susceptible-Infected-Susceptible (SIS) epidemics on networks. We consider a population game framework where nodes choose whether or not to vaccinate themselves, and the epidemic risk is…

Computer Science and Game Theory · Computer Science 2019-03-05 Ashish R. Hota , Shreyas Sundaram

The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

Optimization and Control · Mathematics 2021-09-22 David Rey , Ahmed W Hammad , Meead Saberi

In the face of serious infectious diseases, governments endeavour to implement containment measures such as public vaccination at a macroscopic level. Meanwhile, individuals tend to protect themselves by avoiding contacts with infections at…

Physics and Society · Physics 2016-10-20 Xiao-Long Peng , Xin-Jian Xu , Michael Small , Xinchu Fu , Zhen Jin

Variations in individuals' perceptions of vaccination and decision-making processes can give rise to poor vaccination coverage. The future vaccination promotion programs will benefit from understanding this heterogeneity amongst groups…

Quantitative Methods · Quantitative Biology 2024-11-05 Azadeh Aghaeeyan , Mark A. Lewis , Pouria Ramazi

We consider a SIR model with temporary immunity and time dependent transmission rate. We assume time dependent vaccination which confers the same immunity as natural infection. We study two types of vaccination strategies: i) optimal…

Populations and Evolution · Quantitative Biology 2016-04-06 Paulo Doutor , Paula Rodrigues , Maria do Céu Soares , Fabio A. C. C. Chalub

In this work we propose and investigate a new strategy of vaccination, which we call "dynamic vaccination". In our model, susceptible people become aware that one or more of their contacts are infected, and thereby get vaccinated with…

Physics and Society · Physics 2019-01-09 L. G. Alvarez-Zuzek , M. A. Di Muro , S. Havlin , L. A. Braunstein

The decision of whether or not to vaccinate is a complex one. It involves the contribution both to a social good -- herd immunity -- and to one's own well being. It is informed by social influence, personal experience, education, and mass…

Populations and Evolution · Quantitative Biology 2022-02-15 Soya Miyoshi , Marko Jusup , Petter Holme

We consider the simple epidemiological SIS model for a general heterogeneous population introduced by Lajmanovich and Yorke (1976) in finite dimension, and its infinite dimensional generalization we introduced in previous works. In this…

Dynamical Systems · Mathematics 2022-11-29 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

We investigate methods to vaccinate contact networks -- i.e. removing nodes in such a way that disease spreading is hindered as much as possible -- with respect to their cost-efficiency. Any real implementation of such protocols would come…

Populations and Evolution · Quantitative Biology 2017-11-01 Petter Holme , Nelly Litvak

We study a game-theoretic model of epidemic control in a large population with finitely many groups and non-cooperative individuals. In the model, individuals jointly choose their socialization levels and vaccination rates, and vaccination…

Optimization and Control · Mathematics 2026-04-28 Huaning Liu , Gokce Dayanikli

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

Machine Learning · Computer Science 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan