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Lung cancer is a devastating disease with the highest mortality rate among cancer types. Over 60% of non-small cell lung cancer (NSCLC) patients, which accounts for 87% of diagnoses, require radiation therapy. Rapid treatment initiation…

Image and Video Processing · Electrical Eng. & Systems 2024-08-02 Hamed Hooshangnejad , Xue Feng , Gaofeng Huang , Rui Zhang , Katelyn Kelly , Quan Chen , Kai Ding

Predicting TNM stage is the major determinant of breast cancer prognosis and treatment. The essential part of TNM stage classification is whether the cancer has metastasized to the regional lymph nodes (N-stage). Pathologic N-stage…

Computer Vision and Pattern Recognition · Computer Science 2018-05-31 Byungjae Lee , Kyunghyun Paeng

Diagnosis of breast cancer malignancy at the early stages is a crucial step for controlling its side effects. Histopathological analysis provides a unique opportunity for malignant breast cancer detection. However, such a task would be…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Ardavan Modarres , Erfan Ebrahim Esfahani , Mahsa Bahrami

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

The high-dimensional feature space of the hyperspectral imagery poses major challenges to the processing and analysis of the hyperspectral data sets. In such a case, dimensionality reduction is necessary to decrease the computational…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Mustafa Ustuner

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Chronic Pulmonary Aspergillosis (CPA) is a complex lung disease caused by infection with Aspergillus. Computed tomography (CT) images are frequently requested in patients with suspected and established disease, but the radiological signs on…

Image and Video Processing · Electrical Eng. & Systems 2019-02-08 Mario Zusag , Sujal Desai , Marcello Di Paolo , Thomas Semple , Anand Shah , Elsa Angelini

In this paper, we present a deep learning segmentation approach to classify and quantify the two most prevalent primary liver cancers - hepatocellular carcinoma and intrahepatic cholangiocarcinoma - from hematoxylin and eosin (H&E) stained…

Computer Vision and Pattern Recognition · Computer Science 2023-02-06 Miriam Hägele , Johannes Eschrich , Lukas Ruff , Maximilian Alber , Simon Schallenberg , Adrien Guillot , Christoph Roderburg , Frank Tacke , Frederick Klauschen

We present a fully automated, anatomically guided deep learning pipeline for prostate cancer (PCa) risk stratification using routine MRI. The pipeline integrates three key components: an nnU-Net module for segmenting the prostate gland and…

Lung cancer stands as the preeminent cause of cancer-related mortality globally. Prompt and precise diagnosis, coupled with effective treatment, is imperative to reduce the fatality rates associated with this formidable disease. This study…

Image and Video Processing · Electrical Eng. & Systems 2024-08-29 Bitasadat Jamshidi , Nastaran Ghorbani , Mohsen Rostamy-Malkhalifeh

Reliable and automatic segmentation of lung lobes is important for diagnosis, assessment, and quantification of pulmonary diseases. The existing techniques are prohibitively slow, undesirably rely on prior (airway/vessel) segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Abdullah-Al-Zubaer Imran , Ali Hatamizadeh , Shilpa P. Ananth , Xiaowei Ding , Demetri Terzopoulos , Nima Tajbakhsh

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Analysis of cancer and other pathological diseases, like the interstitial lung diseases (ILDs), is usually possible through Computed Tomography (CT) scans. To aid this, a preprocessing step of segmentation is performed to reduce the area to…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Jeovane Honório Alves , Pedro Martins Moreira Neto , Lucas Ferrari de Oliveira

Ultrasound imaging plays a critical role in the early detection of breast cancer. Accurate identification and segmentation of lesions are essential steps in clinical practice, requiring methods to assist physicians in lesion segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Xin Yue , Xiaoling Liu , Qing Zhao , Jianqiang Li , Changwei Song , Suqin Liu , Zhikai Yang , Guanghui Fu

Predicting outcomes, such as survival or metastasis for individual cancer patients is a crucial component of precision oncology. Machine learning (ML) offers a promising way to exploit rich multi-modal data, including clinical information…

Machine Learning · Computer Science 2021-06-04 Michal Kazmierski , Benjamin Haibe-Kains

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Philipp Kainz , Michael Pfeiffer , Martin Urschler

Automatic diagnosing lung cancer from Computed Tomography (CT) scans involves two steps: detect all suspicious lesions (pulmonary nodules) and evaluate the whole-lung/pulmonary malignancy. Currently, there are many studies about the first…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Fangzhou Liao , Ming Liang , Zhe Li , Xiaolin Hu , Sen Song

Automatic detection of cancer metastasis from whole slide images (WSIs) is a crucial step for following patient staging and prognosis. Recent convolutional neural network based approaches are struggling with the trade-off between accuracy…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Zixu Zhao , Huangjing Lin , Hao Chen , Pheng-Ann Heng

Bayesian variable selection methods are powerful techniques for fitting and inferring on sparse high-dimensional linear regression models. However, many are computationally intensive or require restrictive prior distributions on model…

Methodology · Statistics 2023-10-10 Alexander C. McLain , Anja Zgodic , Howard Bondell