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FRET measurements can provide dynamic spatial information on length scales smaller than the diffraction limit of light. Several methods exist to measure FRET between fluorophores, including Fluorescence Lifetime Imaging Microscopy (FLIM),…

Quantitative Methods · Quantitative Biology 2017-01-09 Bryan Kaye , Peter J. Foster , Tae Yeon Yoo , Daniel J. Needleman

Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…

Quantitative Methods · Quantitative Biology 2023-08-14 Alexia Stollmann , Jose Garcia-Guirado , Jae-Sang Hong , Hyungsoon Im , Hakho Lee , Jaime Ortega Arroyo , Romain Quidant

(Abridged) We describe a new method to extract spectra of stars from observations of crowded stellar fields with integral field spectroscopy (IFS). Our approach extends the well-established concept of crowded field photometry in images into…

Instrumentation and Methods for Astrophysics · Physics 2015-06-12 Sebastian Kamann , Lutz Wisotzki , Martin M. Roth

Most scenes are illuminated by several light sources, where the traditional assumption of uniform illumination is invalid. This issue is ignored in most color constancy methods, primarily due to the complex spatial impact of multiple light…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Umut Cem Entok , Firas Laakom , Farhad Pakdaman , Moncef Gabbouj

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

There is currently a renewed interest in the development of experimental methods to achieve the elastic characterization of thin films, multilayers and acoustic resonators operating in the GHz range of frequencies. The potentialities of…

Applied Physics · Physics 2019-08-30 Giovanni Carlotti

The per- and polyfluoroalkyl substances (PFAS) constitute a group of organofluorine chemicals treated as the emerging pollutants and currently are of particularly acute concern. These compounds have been employed intensively as surfactants…

We propose the DPSM method, a density-based node clustering approach that automatically determines the number of clusters and can be applied in both data space and graph space. Unlike traditional density-based clustering methods, which…

Machine Learning · Computer Science 2024-11-05 Feiping Nie , Yitao Song , Jingjing Xue , Rong Wang , Xuelong Li

Far-field super-resolution fluorescence microscopy has been rapidly developed for applications ranging from cell biology to nanomaterials. However, it remains a significant challenge to achieve super-resolution imaging at depth in opaque…

Optics · Physics 2024-05-01 Tengfei Wu , YoonSeok Baek , Fei Xia , Sylvain Gigan , Hilton B. de Aguiar

The photon density operator function is used to calculate light beam propagation through turbulent atmosphere. A kinetic equation for the photon distribution function is derived and solved using the method of characteristics. Optical wave…

Quantum Physics · Physics 2009-11-13 G. P. Berman , A. A. Chumak

Fermi surfaces, three-dimensional (3D) abstract interfaces that define the occupied energies of electrons in a solid, are important for characterizing and predicting the thermal, electrical, magnetic, and optical properties of crystalline…

The Coarse-to-Fine Few-Shot (C2FS) task is designed to train models using only coarse labels, then leverages a limited number of subclass samples to achieve fine-grained recognition capabilities. This task presents two main challenges:…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Xin-yang Zhao , Jian Jin , Yang-yang Li , Yazhou Yao

The accuracy in the photometry of a point source depends on the point-spread function (PSF), detector pixelization, and observing strategy. The PSF and pixel response describe the spatial blurring of the source, the pixel scale describes…

Instrumentation and Methods for Astrophysics · Physics 2012-02-02 Johan Samsing , Alex G. Kim

The determination of minority-carrier lifetimes and surface recombination velocities is essential for the development of semiconductor technologies such as solar cells. The recent development of two-photon time-resolved microscopy allows…

Materials Science · Physics 2016-03-28 Benoit Gaury , Paul Haney

Confocal microscopy of fluorescent labeled particles has been used to study the dynamical and structural properties of colloidal and granular matter in real space. Localization algorithms allow for a fully automatized determination of the…

Soft Condensed Matter · Physics 2011-12-08 Marcel Roth , Michael Franzmann , Maria D'Acunzi , Max Kreiter , Günter K. Auernhammer

We experimentally study spatial fluctuations of the local density of states (LDOS) inside three-dimensional random photonic media. The LDOS is probed at many positions inside the random photonic media by measuring emission rates of a large…

Optics · Physics 2010-07-06 M. D. Birowosuto , S. E. Skipetrov , W. L. Vos , A. P. Mosk

We report on a recently developed laser-probing diagnostic which allows direct measurements of ray-deflection angles in one axis, whilst retaining imaging capabilities in the other axis. This allows us to measure the spectrum of angular…

Point-wise localization of individual fluorophores is a critical step in super-resolution microscopy and single particle tracking. Although the methods are limited by the accuracy in localizing individual flourophores, this point-wise…

Biological Physics · Physics 2017-05-08 Martin Lindén , Vladimir Ćurić , Elias Amselem , Johan Elf

We propose the use of a frequency-dependent photothermal measurement as a complement to light-flash, i.e. time-dependent, measurements to determine the through-plane thermal diffusivity of small, thin samples, e.g. semiconducting polymers…

Materials Science · Physics 2018-11-14 Maryam Shahi , J. W. Brill

In this two-part paper, we present a novel framework and methodology to analyze data from certain image-based biochemical assays, e.g., ELISPOT and Fluorospot assays. In this first part, we start by presenting a physical partial…

Signal Processing · Electrical Eng. & Systems 2018-10-19 Pol del Aguila Pla , Joakim Jaldén
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