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Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

Optics · Physics 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Advanced microscopy techniques are essential in biomedical research for visualising and tracking biomolecules within living cells and their compartments. Conventional fluorescence microscopy methods, however, often struggle with accurately…

Polytetrafluoroethylene (PTFE) is an excellent diffuse reflector widely used in light collection systems for particle physics experiments. In noble element systems, it is often coated with tetraphenyl butadiene (TPB) to allow detection of…

Instrumentation and Detectors · Physics 2023-03-22 J. Haefner , A. Fahs , J. Ho , C. Stanford , R. Guenette , C. Adams , H. Almazán , V. Álvarez , B. Aparicio , A. I. Aranburu , L. Arazi , I. J. Arnquist , F. Auria-Luna , S. Ayet , C. D. R. Azevedo , K. Bailey , F. Ballester , J. M. Benlloch-Rodríguez , F. I. G. M. Borges , S. Bounasser , N. Byrnes , S. Cárcel , J. V. Carrión , S. Cebrián , E. Church , C. A. N. Conde , T. Contreras , F. P. Cossío , A. A. Denisenko , E. Dey , G. Díaz , T. Dickel , J. Escada , R. Esteve , R. Felkai , L. M. P. Fernandes , P. Ferrario , A. L. Ferreira , F. W. Foss , E. D. C. Freitas , Z. Freixa , J. Generowicz , A. Goldschmidt , J. J. Gómez-Cadenas , R. González , J. Grocott , K. Hafidi , J. Hauptman , C. A. O. Henriques , J. A. Hernando Morata , P. Herrero-Gómez , V. Herrero , P. Ho , Y. Ifergan , B. J. P. Jones , M. Kekic , L. Labarga , L. Larizgoitia , P. Lebrun , D. Lopez Gutierrez , N. López-March , R. Madigan , R. D. P. Mano , J. Martín-Albo , G. Martínez-Lema , M. Martínez-Vara , A. P. Marques , Z. E. Meziani , R. Miller , K. Mistry , J. Molina-Canteras , F. Monrabal , C. M. B. Monteiro , F. J. Mora , J. Muñoz Vidal , K. Navarro , P. Novella , A. Nuñez , D. R. Nygren , E. Oblak , M. Odriozola-Gimeno , B. Palmeiro , A. Para , M. Querol , A. B. Redwine , J. Renner , I. Rivilla , J. Rodríguez , C. Rogero , L. Rogers , B. Romeo , C. Romo-Luque , F. P. Santos , J. M. F. dos Santos , A. Simón , M. Sorel , J. M. R. Teixeira , J. F. Toledo , J. Torrent , A. Usón , J. F. C. A. Veloso , T. T. Vuong , J. Waiton

New arguments supporting the reality of large-scale fluctuations in the density of the visible matter in deep galaxy surveys are presented. A statistical analysis of the radial distributions of galaxies in the COSMOS and HDF-N deep fields…

Cosmology and Nongalactic Astrophysics · Physics 2016-07-12 S. I. Shirokov , N. Yu. Lovyagin , Yu. V. Baryshev , V. L. Gorokhov

We measure the statistical distribution of the local density of optical states (LDOS) on disordered semi-continuous metal films. We show that LDOS fluctuations exhibit a maximum in a regime where fractal clusters dominate the film surface.…

Optics · Physics 2015-05-19 V. Krachmalnicoff , E. Castanié , Y. De Wilde , R. Carminati

A protein undergoes conformational dynamics with multiple time scales, which results in fluctuating enzyme activities. Recent studies in single molecule enzymology have observe this "age-old" dynamic disorder phenomenon directly. However,…

Biomolecules · Quantitative Biology 2009-11-10 Zhanghan Wu , Vlad Elgart , Hong Qian , Jianhua Xing

Taking advantage of the exceptional capabilities of ACS on board of HST, we derive Surface Brightness Fluctuation (SBF) measurements in the B and I bands from images of six elliptical galaxies with $1500 \leq cz \leq 3500$. Given the low…

Extending super-resolution imaging techniques to objects hidden in strongly scattering media potentially revolutionize the technical analysis for much broader categories of samples, such as biological tissues. The main challenge is the…

Line-based density plots are used to reduce visual clutter in line charts with a multitude of individual lines. However, these traditional density plots are often perceived ambiguously, which obstructs the user's identification of…

Graphics · Computer Science 2023-11-23 Yumeng Xue , Patrick Paetzold , Rebecca Kehlbeck , Bin Chen , Kin Chung Kwan , Yunhai Wang , Oliver Deussen

Several devices for substrate texture detection based on diffractive optics, for paper, textiles and non-wovens have been proposed in the past for direct inspection during the production processes. In spite of the presence of devices…

Popular Physics · Physics 2008-01-21 Amelia Sparavigna , Rory A. Wolf

Recently introduced angular-memory-effect based techniques enable non-invasive imaging of objects hidden behind thin scattering layers. However, both the speckle-correlation and the bispectrum analysis are based on the statistical average…

Optics · Physics 2017-11-22 Tengfei Wu , Jonathan Dong , Xiaopeng Shao , Sylvain Gigan

Brillouin Light Scattering is a powerful technique to measure the microwave excitations present in a magnetic system. In microfocused mode, the light is focused on the sample using a microscope objective. This accelerates substantially the…

Mesoscale and Nanoscale Physics · Physics 2025-06-30 Nessrine Benaziz , Thibaut Devolder , Jean-Paul Adam

Hyperuniformity characterizes a state of matter for which density fluctuations diminish towards zero at the largest length scales. However, the task of determining whether or not an experimental system is hyperuniform is experimentally…

Soft Condensed Matter · Physics 2015-06-22 Remi Dreyfus , Ye Xu , Tim Still , Lawrence A. Hough , A. G. Yodh , Salvatore Torquato

In this paper we propose a new approach to identify melanoma diseases by identifying the distribution of its main skin chromophores (melanin, oxyhemoglobin and deoxyhemoglobin) from multispectral dermatological images. Based on Blind Source…

Medical Physics · Physics 2023-09-22 Mustapha Zokay , Hicham Saylani

Mass density is a vital property for improved biophysical understanding of and within biological samples. It is increasingly attracting active investigation, but still lacks reliable, non-contact techniques to accurately characterize it in…

Soft Condensed Matter · Physics 2025-08-12 Conrad Möckel , Jiarui Li , Giulia Zanini , Jochen Guck , Giuliano Scarcelli

Photometric pipelines struggle to estimate both the flux and flux uncertainty for stars in the presence of structured backgrounds such as filaments or clouds. However, it is exactly stars in these complex regions that are critical to…

Instrumentation and Methods for Astrophysics · Physics 2022-07-20 Andrew K. Saydjari , Douglas P. Finkbeiner

A new method is presented for determining the Point Spread Function (PSF) of images that lack bright and isolated stars. It is based on the same principles as the MCS (Magain, Courbin, Sohy, 1998) image deconvolution algorithm. It uses the…

Astrophysics · Physics 2009-11-11 P. Magain , F. Courbin , M. Gillon , S. Sohy , G. Letawe , V. Chantry , Y. Letawe

The knowledge of the exact structure of the optical system PSF enables a high-quality image reconstruction in fluorescence microscopy. Accurate PSF models account for the vector nature of light and the phase and amplitude modifications.…

We report, for the first time, a multi-confocal Fluorescence Correlation Spectroscopy (mFCS) technique which allows parallel measurements at different locations, by combining a Spatial Light Modulator (SLM), with an Electron Multiplying-CCD…

We study fluctuations of particle absorption by a three-dimensional domain with multiple absorbing patches. The domain is in contact with a gas of interacting diffusing particles. This problem is motivated by living cell sensing via…

Statistical Mechanics · Physics 2017-06-28 Tal Agranov , Baruch Meerson
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