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The COVID-19 pandemic has highlighted the need to upgrade systems for infectious disease surveillance and forecasting and modeling of the spread of infection, both of which inform evidence-based public health guidance and policies. Here, we…

The SIR pandemic model suffers from an unrealistic assumption: The rate of removal from the infectious class of individuals is assumed to be proportional to the number of infectious individuals. This means that a change in the rate of…

Populations and Evolution · Quantitative Biology 2021-02-23 Paul A. Reiser

We extend the classical SIR model of infectious disease spread to account for time dependence in the parameters, which also include diffusivities. The temporal dependence accounts for the changing characteristics of testing, quarantine and…

Populations and Evolution · Quantitative Biology 2020-07-03 Zhenlin Wang , Xiaoxuan Zhang , Gregory Teichert , Mariana Carrasco-Teja , Krishna Garikipati

This paper develops an individual-based stochastic network SIR model for the empirical analysis of the Covid-19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic…

Econometrics · Economics 2022-01-05 M. Hashem Pesaran , Cynthia Fan Yang

In the context of natural disasters, human responses inevitably intertwine with natural factors. The COVID-19 pandemic, as a significant stress factor, has brought to light profound variations among different countries in terms of their…

Physics and Society · Physics 2024-02-26 Innokentiy Kastalskiy , Andrei Zinovyev , Evgeny Mirkes , Victor Kazantsev , Alexander N. Gorban

The recent coronavirus disease (COVID-19) outbreak has dramatically increased the public awareness and appreciation of the utility of dynamic models. At the same time, the dissemination of contradictory model predictions has highlighted…

Populations and Evolution · Quantitative Biology 2020-06-26 Gemma Massonis , Julio R. Banga , Alejandro F. Villaverde

The COronaVIrus Disease 2019 (COVID-19) pandemic that has had the world in its grip from the beginning of 2020, has resulted in an unprecedented level of public interest and media attention on the field of mathematical epidemiology. Ever…

Other Quantitative Biology · Quantitative Biology 2022-03-25 Sitabhra Sinha

The spreading dynamics of infectious diseases is influenced by individual behaviours, which are in turn affected by the level of awareness about the epidemic. Modelling the co-evolution of disease transmission and behavioural changes within…

Physics and Society · Physics 2026-02-27 Daniele Proverbio , Riccardo Tessarin , Giulia Giordano

Mathematical modelling of the spread of epidemics has been an interesting challenge in the field of epidemiology. The SIR Model proposed by Kermack and McKendrick in 1927 is a prototypical model of epidemiology. However, it has its…

Populations and Evolution · Quantitative Biology 2021-04-13 Agniva Datta , Muktish Acharyya

A model of reactive social distancing in epidemics is proposed, in which the infection rate changes with the number infected. The final-size equation for the total number that the epidemic will infect can be derived analytically, as can the…

Populations and Evolution · Quantitative Biology 2020-03-19 Rose Baker

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

This paper addresses statistical modelling and forecasting of key indicators describing the severity of a developing pandemic, using routinely reported daily counts of infections, hospitalizations, deaths (both in and out of hospital), and…

The fast transmission rate of COVID-19 worldwide has made this virus the most important challenge of year 2020. Many mitigation policies have been imposed by the governments at different regional levels (country, state, county, and city) to…

Applications · Statistics 2022-05-04 Yue Bai , Abolfazl Safikhani , George Michailidis

We examine the age-structured SIR model, a variant of the classical Susceptible-Infected-Recovered (SIR) model of epidemic propagation, in the context of COVID-19. In doing so, we provide a theoretical basis for the model, perform an…

Optimization and Control · Mathematics 2022-03-11 Rohit Parasnis , Ryosuke Kato , Amol Sakhale , Massimo Franceschetti , Behrouz Touri

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

The estimate of the remaining time of an ongoing wave of epidemic spreading is a critical issue. Due to the variations of a wide range of parameters in an epidemic, for simple models such as Susceptible-Infected-Removed (SIR) model, it is…

Populations and Evolution · Quantitative Biology 2021-10-12 Anvesh Reddy , Hanesh Koganti , Sai Krishna , Suhas Reddy , Soumyajyoti Biswas

OBJECTIVES: to describe the first wave of the COVID-19 pandemic with a focus on undetected cases and to evaluate different post-lockdown scenarios. DESIGN: the study introduces a SEIR compartmental model, taking into account the…

Populations and Evolution · Quantitative Biology 2021-06-03 Nicola Picchiotti , Monica Salvioli , Elena Zanardini , Francesco Missale

The purpose of this work is to give a contribution to the understanding of the COVID-19 contagion in Italy. To this end, we developed a modified Susceptible-Infected-Recovered (SIR) model for the contagion, and we used official data of the…

Physics and Society · Physics 2020-04-01 Giuseppe C. Calafiore , Carlo Novara , Corrado Possieri

The Covid-19 pandemic has two key properties: (i) asymptomatic cases (both detected and undetected) that can result in new infections, and (ii) time-varying characteristics due to new variants, Non-Pharmaceutical Interventions etc. We…

Populations and Evolution · Quantitative Biology 2022-10-26 Manindra Agrawal , Madhuri Kanitkar , Deepu Phillip , Tanima Hajra , Arti Singh , Avaneesh Singh , Prabal Pratap Singh , Mathukumalli Vidyasagar

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing…