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Numerous multi-objective optimization problems encounter with a number of fitness functions to be simultaneously optimized of which their mutual preferences are not inherently known. Suffering from the lack of underlying generative models,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Arash Broumand

DNA sequence encoding is fundamental to gene function prediction, protein synthesis, and diverse downstream biological tasks. Despite the substantial progress achieved by large-scale DNA sequence pretraining, existing studies have…

Machine Learning · Computer Science 2026-04-21 Zhijiang Tang , Jiaxin Qi , Yan Cui , Jinli Ou , Yuhua Zheng , Jianqiang Huang

In the near future, all the human genes will be identified. But understanding the functions coded in the genes is a much harder problem. For example, by using block entropy, one has that the DNA code is closer to a random code then written…

Numerical Analysis · Mathematics 2007-07-13 Torbjörn Lundh

Formal methods apply algorithms based on mathematical principles to enhance the reliability of systems. It would only be natural to try to progress from verification, model checking or testing a system against its formal specification into…

Software Engineering · Computer Science 2014-02-28 Gal Katz , Doron Peled

Genetic algorithms, computer programs that simulate natural evolution, are increasingly applied across many disciplines. They have been used to solve various optimisation problems from neural network architecture search to strategic games,…

Neural and Evolutionary Computing · Computer Science 2021-09-14 Aymeric Vie , Alissa M. Kleinnijenhuis , Doyne J. Farmer

The code written by developers usually suffers from efficiency problems and contain various performance bugs. These inefficiencies necessitate the research of automated refactoring methods for code optimization. Early research in code…

Software Engineering · Computer Science 2024-08-23 Shuzheng Gao , Cuiyun Gao , Wenchao Gu , Michael Lyu

In this paper the approach to solving several combinatorial optimization problems using the local search and the genetic algorithm techniques is proposed. Initially this approach was developed in purpose to overcome some difficulties…

Neural and Evolutionary Computing · Computer Science 2010-04-30 Anton Bondarenko

Real world problems always have different multiple solutions. For instance, optical engineers need to tune the recording parameters to get as many optimal solutions as possible for multiple trials in the varied-line-spacing holographic…

Neural and Evolutionary Computing · Computer Science 2015-08-04 Ka-Chun Wong

Detectability of failures of linear programming (LP) decoding and the potential for improvement by adding new constraints motivate the use of an adaptive approach in selecting the constraints for the underlying LP problem. In this paper, we…

Information Theory · Computer Science 2007-07-13 Mohammad H. Taghavi , Paul H. Siegel

The genes that encode the targets of most therapies do not have rare variants with large-effect or common variants with moderate effects on the biomarker reflecting the pharmacologic action of the corresponding therapy. Therefore, providing…

Quantitative Methods · Quantitative Biology 2020-07-28 B. A. Ference , G. Davey Smith , M. V. Holmes , A. L. Catapano , K. K. Ray , S. J. Nicholls

The immense amounts of source code provide ample challenges and opportunities during software development. To handle the size of code bases, developers commonly search for code, e.g., when trying to find where a particular feature is…

Software Engineering · Computer Science 2022-10-06 Luca Di Grazia , Michael Pradel

Over the last decades, hand-crafted feature extractors have been used to encode image visual properties into feature vectors. Recently, data-driven feature learning approaches have been successfully explored as alternatives for producing…

Computer Vision and Pattern Recognition · Computer Science 2020-11-25 Érico M. Pereira , Ricardo da S. Torres , Jefersson A. dos Santos

It has been widely recognized that the performance of a multi-agent system is highly affected by its organization. A large scale system may have billions of possible ways of organization, which makes it impractical to find an optimal choice…

Multiagent Systems · Computer Science 2014-11-25 Zhiqi Shen , Ling Yu , Han Yu

This paper provides experimental experiences on two local search hybridized genetic algorithms in solving the uncapacitated examination timetabling problem. The proposed two hybrid algorithms use partition and priority based solution…

Neural and Evolutionary Computing · Computer Science 2023-06-02 Ayse Aslan

The genetic code is the set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells. The code defines a mapping between tri-nucleotide sequences,…

Other Quantitative Biology · Quantitative Biology 2015-12-03 Jayanta Kumar Das , Atrayee Majumder , Pabitra Pal Choudhury

The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

Quantitative Methods · Quantitative Biology 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

An anytime decoding algorithm for tree codes using Monte-Carlo tree search is proposed. The meaning of anytime decoding here is twofold: 1) the decoding algorithm is an anytime algorithm, whose decoding performance improves as more…

Information Theory · Computer Science 2021-05-04 Aolin Xu

All living organisms use the same genetic languages in their molecular biology machinery. They can be understood as the optimal solutions to the replication tasks involving DNA and proteins. These solutions perfectly fit the pattern…

Other Quantitative Biology · Quantitative Biology 2025-05-21 Apoorva D. Patel

Complex systems with tightly coadapted parts frequently appear in living systems and are difficult to account for through Darwinian evolution, that is random variation and natural selection, if the constituent parts are independently coded…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 John F. McGowan , Ph. D

The representation, or encoding, utilized in evolutionary algorithms has a substantial effect on their performance. Examination of the suitability of widely used representations for quality diversity optimization (QD) in robotic domains has…

Neural and Evolutionary Computing · Computer Science 2023-04-10 Ludovico Scarton , Alexander Hagg