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Most sensory cells use surface receptors to detect environmental stimuli and initiate downstream signaling. Cooperative interactions among sensory receptors is known to play a crucial role in enhancing the sensitivity of biochemical…

Molecular Networks · Quantitative Biology 2014-01-15 Jianmin Sun , Michael Grabe

A hub-based colony consists of multiple agents who share a common nest site called the hub. Agents perform tasks away from the hub like foraging for food or gathering information about future nest sites. Modeling hub-based colonies is…

Multiagent Systems · Computer Science 2024-08-12 Puneet Jain , Chaitanya Dwivedi , Vigynesh Bhatt , Nick Smith , Michael A Goodrich

Robotic systems often use predictive uncertainty to decide whether to act autonomously or defer to a fallback policy. In threshold-gated autonomy, uncertainty matters mainly through its ability to rank likely errors. Standard metrics such…

Robotics · Computer Science 2026-05-19 Johannes A. Gaus , Jhon P. F. Charaja , Daniel Haeufle

Outcomes of data-driven AI models cannot be assumed to be always correct. To estimate the uncertainty in these outcomes, the uncertainty wrapper framework has been proposed, which considers uncertainties related to model fit, input quality,…

Machine Learning · Computer Science 2022-01-11 Pascal Gerber , Lisa Jöckel , Michael Kläs

Policy gradient (PG) methods are successful approaches to deal with continuous reinforcement learning (RL) problems. They learn stochastic parametric (hyper)policies by either exploring in the space of actions or in the space of parameters.…

Machine Learning · Computer Science 2024-05-31 Alessandro Montenegro , Marco Mussi , Alberto Maria Metelli , Matteo Papini

Visualizing the uncertainty of ensemble simulations is challenging due to the large size and multivariate and temporal features of ensemble data sets. One popular approach to studying the uncertainty of ensembles is analyzing the positional…

Machine Learning · Computer Science 2022-10-25 Mengjiao Han , Tushar M. Athawale , David Pugmire , Chris R. Johnson

Mass is a fundamental property of galaxy groups and clusters. In theory weak gravitational lensing will enable an approximately unbiased measurement of mass, but parametric methods for extracting cluster masses from data require the…

Cosmology and Nongalactic Astrophysics · Physics 2017-05-31 Maggie Lieu , Will M. Farr , Michael Betancourt , Graham P. Smith , Mauro Sereno , Ian G. McCarthy

Distributed processing over networks relies on in-network processing and cooperation among neighboring agents. Cooperation is beneficial when agents share a common objective. However, in many applications agents may belong to different…

Optimization and Control · Mathematics 2023-07-19 Xiaochuan Zhao , Ali H. Sayed

Link prediction is an open problem in the complex network, which attracts much research interest currently. However, little attention has been paid to the relation between network structure and the performance of prediction methods. In…

Social and Information Networks · Computer Science 2014-10-28 Xu Feng , Jichang Zhao , Ke Xu

Learning invariant representations is an important requirement when training machine learning models that are driven by spurious correlations in the datasets. These spurious correlations, between input samples and the target labels, wrongly…

Machine Learning · Computer Science 2022-01-12 Vishnu Suresh Lokhande , Kihyuk Sohn , Jinsung Yoon , Madeleine Udell , Chen-Yu Lee , Tomas Pfister

Intracellular transport is based on molecular motors that pull cargos along cytoskeletal filaments. One motor species always moves in one direction, e.g. conventional kinesin moves to the microtubule plus end, while cytoplasmic dynein moves…

Subcellular Processes · Quantitative Biology 2008-07-04 Melanie J. I. Müller , Stefan Klumpp , Reinhard Lipowsky

Model-based clustering is a powerful tool that is often used to discover hidden structure in data by grouping observational units that exhibit similar response values. Recently, clustering methods have been developed that permit…

Methodology · Statistics 2025-06-24 Sally Paganin , Garritt L. Page , Fernando Andrés Quintana

Understanding and explaining deep learning models is an imperative task. Towards this, we propose a method that obtains gradient-based certainty estimates that also provide visual attention maps. Particularly, we solve for visual question…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Badri N. Patro , Mayank Lunayach , Vinay P. Namboodiri

The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…

Cell Behavior · Quantitative Biology 2007-05-23 Radek Erban , Hans G. Othmer

Cell signaling networks are complex and often incompletely characterized, making it difficult to obtain a comprehensive picture of the mechanisms they encode. Mathematical modeling of these networks provides important clues, but the models…

Molecular Networks · Quantitative Biology 2022-11-07 Soutick Saha , Hye-ran Moon , Bumsoo Han , Andrew Mugler

Graph contrastive learning (GCL) aims to learn discriminative semantic invariance by contrasting different views of the same graph that share critical topological patterns. However, existing GCL approaches with structural augmentations…

Machine Learning · Computer Science 2025-12-03 Qirui Ji , Bin Qin , Yifan Jin , Yunze Zhao , Chuxiong Sun , Changwen Zheng , Jianwen Cao , Jiangmeng Li

Identifying clusters of vertices in graphs continues to be an important problem, and modularity continues to be used as a tool for solving the problem. Modularity, which measures the quality of a division of the vertices into clusters,…

Social and Information Networks · Computer Science 2021-09-13 Larry Wilson

Clustering under pairwise constraints is an important knowledge discovery tool that enables the learning of appropriate kernels or distance metrics to improve clustering performance. These pairwise constraints, which come in the form of…

Machine Learning · Computer Science 2022-03-24 Benedikt Boecking , Vincent Jeanselme , Artur Dubrawski

In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

Machine Learning · Statistics 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

We show how the competition between sensing and adaptation can result in a performance peak in E.coli chemotaxis using extensive numerical simulations in a detailed theoretical model. Receptor clustering amplifies the input signal coming…

Cell Behavior · Quantitative Biology 2021-03-17 Shobhan Dev Mandal , Sakuntala Chatterjee