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Self-generated gradients (SGG) provide robust steering cues that guide cells in their long-distance expeditions during embryonic development, immune response, and cancer metastasis. Cells generate their own local, dynamic gradients by…

Soft Condensed Matter · Physics 2021-09-29 Himadri S Samanta

The environment plays a critical role in galaxy evolution, with galaxy clusters and their infall regions offering diverse conditions that shape galaxies before they enter the dense cluster core, a process known as ``pre-processing''.…

Astrophysics of Galaxies · Physics 2026-05-15 Rhys Jordan , Meghan E. Gray , Alfonso Aragón-Salamanca , Steven P. Bamford , Frazer R. Pearce , Roan Haggar

We put forward a new model of congestion games where agents have uncertainty over the routes used by other agents. We take a non-probabilistic approach, assuming that each agent knows that the number of agents using an edge is within a…

Computer Science and Game Theory · Computer Science 2017-03-28 Reshef Meir , David Parkes

Understanding and explaining deep learning models is an imperative task. Towards this, we propose a method that obtains gradient-based certainty estimates that also provide visual attention maps. Particularly, we solve for visual question…

Computer Vision and Pattern Recognition · Computer Science 2019-10-18 Badri N. Patro , Mayank Lunayach , Shivansh Patel , Vinay P. Namboodiri

Deep neural networks are often ignorant about what they do not know and overconfident when they make uninformed predictions. Some recent approaches quantify classification uncertainty directly by training the model to output high…

Machine Learning · Computer Science 2020-06-09 Murat Sensoy , Lance Kaplan , Federico Cerutti , Maryam Saleki

The problem of clustering large complex networks plays a key role in several scientific fields ranging from Biology to Sociology and Computer Science. Many approaches to clustering complex networks are based on the idea of maximizing a…

Social and Information Networks · Computer Science 2013-10-17 Pasquale De Meo , Emilio Ferrara , Giacomo Fiumara , Alessandro Provetti

We investigate the boundary between chemotaxis driven by spatial estimation of gradients and chemotaxis driven by temporal estimation. While it is well known that spatial chemotaxis becomes disadvantageous for small organisms at high noise…

Neural and Evolutionary Computing · Computer Science 2024-06-18 Albert Alonso , Julius B. Kirkegaard

A cell routinely responds to one of many competing environmental cues. A fundamental question is whether the cell follows the cue prioritized by its internal signaling network or the cue that carries the most external information. We…

Biological Physics · Physics 2025-06-26 Louis Gonzalez , Hogyeong Gwak , Bumsoo Han , Andrew Mugler

Human mobility clustering is an important problem for understanding human mobility behaviors (e.g., work and school commutes). Existing methods typically contain two steps: choosing or learning a mobility representation and applying a…

Machine Learning · Computer Science 2023-01-23 Haoji Hu , Haowen Lin , Yao-Yi Chiang

Clustering is a fundamental learning task widely used as a first step in data analysis. For example, biologists use cluster assignments to analyze genome sequences, medical records, or images. Since downstream analysis is typically…

Machine Learning · Computer Science 2024-06-11 Jonathan Svirsky , Ofir Lindenbaum

Temporal data, obtained in the setting where it is only possible to observe one time point per experiment, is widely used in different research fields, yet remains insufficiently addressed from the statistical point of view. Such data often…

Methodology · Statistics 2025-03-10 Polina Arsenteva , Mohamed Amine Benadjaoud , Hervé Cardot

The ability of biological and artificial collectives to outperform solitary individuals in a wide variety of tasks depends crucially on the efficient processing of social and environmental information at the level of the collective. Here,…

Biological Physics · Physics 2020-10-13 Parisa Rahmani , Fernando Peruani , Pawel Romanczuk

To successfully navigate chemical gradients, microorganisms need to predict how the ligand concentration changes in space. Due to their limited size, they do not take a spatial derivative over their body length but rather a temporal…

Molecular Networks · Quantitative Biology 2024-02-09 Age J. Tjalma , Pieter Rein ten Wolde

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Aleksei Shpilman , Dmitry Boikiy , Marina Polyakova , Daniel Kudenko , Anton Burakov , Elena Nadezhdina

Selective classification allows models to abstain from making predictions (e.g., say "I don't know") when in doubt in order to obtain better effective accuracy. While typical selective models can be effective at producing more accurate…

Machine Learning · Computer Science 2024-06-24 Adam Fisch , Tommi Jaakkola , Regina Barzilay

People organize in groups and contagions spread across them. A simple stochastic process, yet complex to model due to dynamical correlations within and between groups. Moreover, groups can evolve if agents join or leave in response to…

Physics and Society · Physics 2025-05-22 Giulio Burgio , Guillaume St-Onge , Laurent Hébert-Dufresne

It is a challenge to predict the response of a large, complex system to a perturbation. Recent attempts to predict the behaviour of food webs have revealed that the effort needed to understand a system grows quickly with its complexity,…

Populations and Evolution · Quantitative Biology 2013-11-07 Helge Aufderheide , Lars Rudolf , Thilo Gross , Kevin D. Lafferty

The use of mathematical models to make predictions about tumor growth and response to treatment has become increasingly more prevalent in the clinical setting. The level of complexity within these models ranges broadly, and the calibration…

Quantitative Methods · Quantitative Biology 2021-12-28 Allison L. Lewis , Kathleen M. Storey , Heyrim Cho , Anna C. Zittle

A cognitive radio system has the ability to observe and learn from the environment, adapt to the environmental conditions, and use the radio spectrum more efficiently. However, due to multipath fading, shadowing, or varying channel…

Information Theory · Computer Science 2017-01-20 Fatima Salahdine , Naima Kaabouch , Hassan Ghazi

We consider the problem of classification of points sampled from an unknown probability measure on a Euclidean space. We study the question of querying the class label at a very small number of judiciously chosen points so as to be able to…

Machine Learning · Computer Science 2020-12-09 Alexander Cloninger , Hrushikesh Mhaskar
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