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As dynamical systems equipped with neural network controllers (neural feedback systems) become increasingly prevalent, it is critical to develop methods to ensure their safe operation. Verifying safety requires extending control theoretic…

Systems and Control · Electrical Eng. & Systems 2026-04-15 I. Samuel Akinwande , Chelsea Sidrane , Mykel J. Kochenderfer , Clark Barrett

The optimal design of multi-target rendezvous and flyby missions is challenging due to the combination of traditional spacecraft trajectory optimization and high-dimensional combinatorial problems. This often requires large-scale global…

Instrumentation and Methods for Astrophysics · Physics 2025-01-24 Jack Yarndley , Harry Holt , Roberto Armellin

Machine Learning models are increasingly used for decision making, in particular in high-stakes applications such as credit scoring, medicine or recidivism prediction. However, there are growing concerns about these models with respect to…

Machine Learning · Computer Science 2023-04-12 Julien Rouzot , Julien Ferry , Marie-José Huguet

The optimization of expensive to evaluate, black-box, mixed-variable functions, i.e. functions that have continuous and discrete inputs, is a difficult and yet pervasive problem in science and engineering. In Bayesian optimization (BO),…

Machine Learning · Computer Science 2020-08-05 Erik Daxberger , Anastasia Makarova , Matteo Turchetta , Andreas Krause

In this paper, we propose a new mixed-integer linear programming (MILP) model ontology and a novel constraint typology of MILP formulations. MILP is a commonly used mathematical programming technique for modelling and solving real-life…

Artificial Intelligence · Computer Science 2021-03-02 Bahadorreza Ofoghi , Vicky Mak , John Yearwood

In this work, we develop an adaptive, multivariate partitioning algorithm for solving mixed-integer nonlinear programs (MINLP) with multi-linear terms to global optimality. This iterative algorithm primarily exploits the advantages of…

Optimization and Control · Mathematics 2019-02-05 Harsha Nagarajan , Mowen Lu , Site Wang , Russell Bent , Kaarthik Sundar

Data-driven inverse optimization for mixed-integer linear programs (MILPs), which seeks to learn an objective function and constraints consistent with observed decisions, is important for building accurate mathematical models in a variety…

Optimization and Control · Mathematics 2026-02-17 Akira Kitaoka

The irregular strip-packing problem consists of the computation of a non-overlapping placement of a set of polygons onto a rectangular strip of fixed width and the minimal length possible. Recent performance gains of the Mixed-Integer…

Optimization and Control · Mathematics 2025-04-01 Juan J. Lastra-Díaz , M. Teresa Ortuño

Machine learning components commonly appear in larger decision-making pipelines; however, the model training process typically focuses only on a loss that measures accuracy between predicted values and ground truth values. Decision-focused…

Machine Learning · Computer Science 2019-07-19 Aaron Ferber , Bryan Wilder , Bistra Dilkina , Milind Tambe

When implementing model predictive control (MPC) for hybrid systems with a linear or a quadratic performance measure, a mixed-integer linear program (MILP) or a mixed-integer quadratic program (MIQP) needs to be solved, respectively, at…

Systems and Control · Electrical Eng. & Systems 2025-04-11 Shamisa Shoja , Daniel Arnström , Daniel Axehill

Linear Predictive Clustering (LPC) partitions samples based on shared linear relationships between feature and target variables, with numerous applications including marketing, medicine, and education. Greedy optimization methods, commonly…

Machine Learning · Computer Science 2026-04-08 Jiazhou Liang , Hassan Khurram , Scott Sanner

Binary optimization has a wide range of applications in combinatorial optimization problems such as MaxCut, MIMO detection, and MaxSAT. However, these problems are typically NP-hard due to the binary constraints. We develop a novel…

Optimization and Control · Mathematics 2023-07-04 Cheng Chen , Ruitao Chen , Tianyou Li , Ruichen Ao , Zaiwen Wen

Mixed Binary Quadratic Programs (MBQPs) are an important and complex set of problems in combinatorial optimization. As solving large-scale combinatorial optimization problems is challenging, primal heuristics have been developed to quickly…

Machine Learning · Computer Science 2026-04-28 Weimin Huang , Natalie M. Isenberg , Ján Drgoňa , Draguna L Vrabie , Bistra Dilkina

Space mission planning and spacecraft design are tightly coupled and need to be considered together for optimal performance; however, this integrated optimization problem results in a large-scale Mixed-Integer Nonlinear Programming (MINLP)…

Optimization and Control · Mathematics 2025-08-27 Masafumi Isaji , Yuji Takubo , Koki Ho

In many operational contexts, solutions to NP-hard combinatorial optimization problems, modeled by means of Mixed-Integer Linear Programming (MILP), may become infeasible due to unpredictable disruptions. Typically, reoptimizing by solving…

Optimization and Control · Mathematics 2026-05-27 Mathieu Lerouge , Andrea Lodi , Enrico Malaguti , Michele Monaci , Filippo Focacci

Binary optimization, a representative subclass of discrete optimization, plays an important role in mathematical optimization and has various applications in computer vision and machine learning. Usually, binary optimization problems are…

Optimization and Control · Mathematics 2021-05-18 Huan Xiong , Mengyang Yu , Li Liu , Fan Zhu , Fumin Shen , Ling Shao

When gradient-based methods are impractical, black-box optimization (BBO) provides a valuable alternative. However, BBO often struggles with high-dimensional problems and limited trial budgets. In this work, we propose a novel approach…

Systems and Control · Electrical Eng. & Systems 2025-10-03 Riccardo Busetto , Manas Mejari , Marco Forgione , Alberto Bemporad , Dario Piga

In the last twenty-five years (1990-2014), algorithmic advances in integer optimization combined with hardware improvements have resulted in an astonishing 200 billion factor speedup in solving Mixed Integer Optimization (MIO) problems. We…

Methodology · Statistics 2015-07-14 Dimitris Bertsimas , Angela King , Rahul Mazumder

Mixed Integer Linear Programs (MILPs) are highly flexible and powerful tools for modeling and solving complex real-world combinatorial optimization problems. Recently, machine learning (ML)-guided approaches have demonstrated significant…

Artificial Intelligence · Computer Science 2025-06-13 Junyang Cai , Taoan Huang , Bistra Dilkina

Mixed-Integer Linear Programming (MILP) is a powerful framework used to address a wide range of NP-hard combinatorial optimization problems, often solved by Branch and Bound (B&B). A key factor influencing the performance of B&B solvers is…

Machine Learning · Computer Science 2025-10-23 Paul Strang , Zacharie Alès , Côme Bissuel , Olivier Juan , Safia Kedad-Sidhoum , Emmanuel Rachelson
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