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As depth increases, linear energy transfer (LET) rises toward the distal edge of the Bragg peak, boosting the radiobiological effectiveness (RBE). To manage the biological variation and limit normal-tissue damage, LET-modifying objective…

Medical Physics · Physics 2025-05-22 Lisa Seckler , Amit Ben Antony Bennan , Niklas Wahl

This paper presents a proximal bundle variant, namely, the relaxed proximal bundle (RPB) method, for solving convex nonsmooth composite optimization problems. Like other proximal bundle variants, RPB solves a sequence of prox bundle…

Optimization and Control · Mathematics 2021-06-09 Jiaming Liang , Renato D. C. Monteiro

Robot-assisted laparoscopic prostatectomy (RALP) is a treatment for prostate cancer that involves complete or nerve sparing removal prostate tissue that contains cancer. After removal the bladder neck is successively sutured directly with…

In this paper, a new mixed integer nonlinear programming formulation is proposed for optimally placing and operating pressure reducing valves and chlorine booster stations in water distribution networks. The objective is the minimization of…

Optimization and Control · Mathematics 2021-03-12 Filippo Pecci , Ivan Stoianov , Avi Ostfeld

We propose a novel application of coded computing to the problem of the nearest neighbor estimation using MatDot Codes [Fahim. et.al. 2017], that are known to be optimal for matrix multiplication in terms of recovery threshold under storage…

Information Theory · Computer Science 2018-11-30 Utsav Sheth , Sanghamitra Dutta , Malhar Chaudhari , Haewon Jeong , Yaoqing Yang , Jukka Kohonen , Teemu Roos , Pulkit Grover

Low earth orbit (LEO) satellite communications can provide ubiquitous and reliable services, making it an essential part of the Internet of Everything network. Beam hopping (BH) is an emerging technology for effectively addressing the issue…

Networking and Internet Architecture · Computer Science 2023-12-05 Shuang Zheng , Xing Zhang , Peng Wang , Wenbo Wang

Probabilistic evaluation improves the trade-off between target coverage and OAR sparing in IMPT but remains computationally demanding. This study proposes sparse probabilistic evaluation (SPE), a computationally efficient approach…

Effective transperineal ultrasound image guidance in prostate external beam radiotherapy requires consistent alignment between probe and prostate at each session during patient set-up. Probe placement and ultrasound image inter-pretation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 Alexander Grimwood , Helen McNair , Yipeng Hu , Ester Bonmati , Dean Barratt , Emma Harris

Objective: Intensity-modulated radiation therapy (IMRT) beam angle optimization (BAO) is a challenging combinatorial optimization problem that is NP-hard. In this study, we aim to develop a personalized BAO algorithm for IMRT that improves…

Medical Physics · Physics 2023-03-08 Peng Bao , Gong Wang , Ruijie Yang , Bin Dong

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Objective: Spatiotemporal optimization in radiation therapy involves determining the optimal number of dose delivery fractions (temporal) and the optimal dose per fraction (spatial). Traditional approaches focus on maximizing the…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Wangyao Li , Ronald C Chen , Hao Gao

A new strategy for radiation therapy dosimetry planning (RTDP) used to reduce dose estimation errors due to respiratory motion in breast treatment was illustrated and evaluated in this study. On CT data set acquired for breast treatment,…

Medical Physics · Physics 2021-10-20 Mazen Moussallem , Pauline Harb , Hanane Rima , Zeina Al Kattar , Saad Ayoubi

Inverse planning algorithms for dwell time optimisation in interstitial high-dose-rate (HDR) brachytherapy may produce solutions with large dwell time variations within catheters, which may result in undesirable selective high-dose…

Medical Physics · Physics 2016-03-14 Marleen Balvert , Bram Gorissen , Dick den Hertog , Aswin Hoffmann

Background and Purpose: Reirradiation for non-small cell lung cancer (NSCLC) is commonly delivered using coplanar techniques. In this study, we developed a beam orientation optimization algorithm for reirradiation planning to investigate…

The performance of multi-objective evolutionary algorithms deteriorates appreciably in solving many-objective optimization problems which encompass more than three objectives. One of the known rationales is the loss of selection pressure…

Neural and Evolutionary Computing · Computer Science 2018-02-27 Yanan Sun , Gary G. Yen , Zhang Yi

We propose a novel rolling shutter bundle adjustment method for neural radiance fields (NeRF), which utilizes the unordered rolling shutter (RS) images to obtain the implicit 3D representation. Existing NeRF methods suffer from low-quality…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Bo Xu , Ziao Liu , Mengqi Guo , Jiancheng Li , Gim Hee Lee

Base placement optimization (BPO) is a fundamental capability for mobile manipulation and has been researched for decades. However, it is still very challenging for some reasons. First, compared with humans, current robots are extremely…

Robotics · Computer Science 2023-04-18 Huiwen Zhang , Kai Mi , Zhijun Zhang

This paper introduces a new algorithm for trajectory optimization, Decoupled Reduced-space and Adaptive Feasibility-repair Trajectory Optimization (DRAFTO). It first constructs a constrained objective that accounts for smoothness, safety,…

Robotics · Computer Science 2026-03-13 Yichang Feng , Xiao Liang , Minghui Zheng

Steerable needles are a promising technology for delivering targeted therapies in the body in a minimally-invasive fashion, as they can curve around anatomical obstacles and hone in on anatomical targets. In order to accurately steer them,…

The NEPv approach has been increasingly used lately for optimization on the Stiefel manifold arising from machine learning. General speaking, the approach first turns the first order optimality condition, also known as the KKT condition,…

Optimization and Control · Mathematics 2026-05-08 Ren-Cang Li