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Although bulk transcriptomic analyses have significantly contributed to an enhanced comprehension of multifaceted diseases, their exploration capacity is impeded by the heterogeneous compositions of biological samples. Indeed, by averaging…

Quantitative Methods · Quantitative Biology 2023-10-24 Bastien Chassagnol , Grégory Nuel , Etienne Becht

We introduce a new graphical model for tracking radio-tagged animals and learning their movement patterns. The model provides a principled way to combine radio telemetry data with an arbitrary set of userdefined, spatial features. We…

Machine Learning · Computer Science 2012-03-19 Berk Kapicioglu , Robert E. Schapire , Martin Wikelski , Tamara Broderick

While spatial transcriptomics (ST) has advanced our understanding of gene expression in tissue context, its high experimental cost limits its large-scale application. Predicting ST from pathology images is a promising, cost-effective…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Zhiceng Shi , Changmiao Wang , Jun Wan , Wenwen Min

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Spatial data is playing an emerging role in new technologies such as web and mobile mapping and Geographic Information Systems (GIS). Important decisions in political, social and many other aspects of modern human life are being made using…

Databases · Computer Science 2016-05-17 Bagher Saberi , Nasser Ghadiri

Spatial transcriptomics (ST) is a promising technique that characterizes the spatial gene profiling patterns within the tissue context. Comprehensive ST analysis depends on consecutive slices for 3D spatial insights, whereas the missing…

Image and Video Processing · Electrical Eng. & Systems 2025-05-19 NingFeng Que , Xiaofei Wang , Jingjing Chen , Yixuan Jiang , Chao Li

Many biological and physical systems exhibit behaviour at multiple spatial, temporal or population scales. Multiscale processes provide challenges when they are to be simulated using numerical techniques. While coarser methods such as…

Quantitative Methods · Quantitative Biology 2018-02-12 Cameron A. Smith , Christian A. Yates

Spatial graphs are particular graphs for which the nodes are localized in space (e.g., public transport network, molecules, branching biological structures). In this work, we consider the problem of spatial graph reduction, that aims to…

Machine Learning · Statistics 2026-03-10 Anna Calissano , Etienne Lasalle

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Recent advancements in geographic information systems and mixed reality technologies have positioned spatial computing as a transformative paradigm in computational science. However, the field remains conceptually fragmented, with diverse…

Human-Computer Interaction · Computer Science 2025-09-01 Yibo Wang , Yuhan Luo , Janghee Cho , Junnan Yu

Humans perceive and understand real-world spaces through a stream of visual observations. Therefore, the ability to streamingly maintain and update spatial evidence from potentially unbounded video streams is essential for spatial…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Fangfu Liu , Diankun Wu , Jiawei Chi , Yimo Cai , Yi-Hsin Hung , Xumin Yu , Hao Li , Han Hu , Yongming Rao , Yueqi Duan

With the rapid advances of data acquisition techniques, spatio-temporal data are becoming increasingly abundant in a diverse array of disciplines. Here we develop spatio-temporal regression methodology for analyzing large amounts of…

Methodology · Statistics 2021-12-01 Ting Fung Ma , Fangfang Wang , Jun Zhu , Anthony R. Ives , Katarzyna E. Lewińska

The size of large, geo-located datasets has reached scales where visualization of all data points is inefficient. Random sampling is a method to reduce the size of a dataset, yet it can introduce unwanted errors. We describe a method for…

Human-Computer Interaction · Computer Science 2017-09-14 Yan Zheng , Yi Ou , Alexander Lex , Jeff M. Phillips

Single cell responses are shaped by the geometry of signaling kinetic trajectories carved in a multidimensional space spanned by signaling protein abundances. It is however challenging to assay large number (>3) of signaling species in…

Quantitative Methods · Quantitative Biology 2017-07-27 Sayak Mukherjee , David Stewart , William Stewart , Lewis L. Lanier , Jayajit Das

Higher-order tensors have received increased attention across science and engineering. While most tensor decomposition methods are developed for a single tensor observation, scientific studies often collect side information, in the form of…

Methodology · Statistics 2021-10-29 Jiaxin Hu , Chanwoo Lee , Miaoyan Wang

Many approaches have dealt with the hypothesis that the environment contain information, mostly focusing on how humans decode information from the environment in visual perception, navigation, and spatial decision-making. A question yet to…

Physics and Society · Physics 2019-10-16 Vinicius M. Netto , Edgardo Brigatti , Caio Cacholas , Vinicius Gomes Aleixo

Spatial transcriptomics (ST) technologies enable transcriptome-wide gene expression profiling while preserving spatial resolution, offering unprecedented opportunities to uncover complex spatial structures. Due to the ultra-high…

Applications · Statistics 2026-03-11 Changhu Wang , Qiyun Huang , Zihao Chen , Jin Liu , Ruibin Xi

Spatial computing is a technological advancement that facilitates the seamless integration of devices into the physical environment, resulting in a more natural and intuitive digital world user experience. Spatial computing has the…

We address the problem of tactile localization, where the goal is to identify image regions that share the same material properties as a tactile input. Existing visuo-tactile methods rely on global alignment and thus fail to capture the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Seongyu Kim , Seungwoo Lee , Hyeonggon Ryu , Joon Son Chung , Arda Senocak

Spatial transcriptomics enables gene expression profiling with spatial context, offering unprecedented insights into the tissue microenvironment. However, most computational models treat genes as isolated numerical features, ignoring the…

Machine Learning · Computer Science 2025-11-17 Jiangkai Long , Yanran Zhu , Chang Tang , Kun Sun , Yuanyuan Liu , Xuesong Yan