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This survey is devoted to recent developments in the statistical analysis of spherical data, with a view to applications in Cosmology. We will start from a brief discussion of Cosmological questions and motivations, arguing that most…

Cosmology and Nongalactic Astrophysics · Physics 2023-03-28 Javier Carrón Duque , Domenico Marinucci

Celcomen leverages a mathematical causality framework to disentangle intra- and inter- cellular gene regulation programs in spatial transcriptomics and single-cell data through a generative graph neural network. It can learn gene-gene…

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

Genomics · Quantitative Biology 2025-11-19 Yue Ling , Peiqi Zhang , Zhenyi Zhang , Peijie Zhou

Spatial ecological networks are widely used to model interactions between georeferenced biological entities (e.g., populations or communities). The analysis of such data often leads to a two-step approach where groups containing similar…

Applications · Statistics 2014-02-24 Vincent Miele , Franck Picard , Stéphane Dray

Contact tracing is an essential tool in slowing and containing outbreaks of contagious diseases. Current contact tracing methods range from interviews with public health personnel to Bluetooth pings from smartphones. While all methods offer…

Methodology · Statistics 2024-12-17 K. J. Patten

In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

Dynamics of human body skeletons convey significant information for human action recognition. Conventional approaches for modeling skeletons usually rely on hand-crafted parts or traversal rules, thus resulting in limited expressive power…

Computer Vision and Pattern Recognition · Computer Science 2018-01-26 Sijie Yan , Yuanjun Xiong , Dahua Lin

For the Bio+Med-Vis Challenge 2024, we propose a visual analytics system as a redesign for the scatter pie chart visualization of cell type proportions of spatial transcriptomics data. Our design uses three linked views: a view of the…

Human-Computer Interaction · Computer Science 2024-09-12 David Hägele , Yuxuan Tang , Daniel Weiskopf

Spatial domain identification requires jointly modeling molecular signatures and physical coordinates, yet current tools frequently over-smooth biological boundaries, require user-specified cluster numbers, and lack principled multimodal…

Applications · Statistics 2026-05-18 Xin Li , Xiaofei Dong , Zhenke Duan , Lulu Shang , Xiao Wang , Xinyuan Song , Hanwen Ning , Guanyu Hu

Visual localization is a useful alternative to standard localization techniques. It works by utilizing cameras. In a typical scenario, features are extracted from captured images and compared with geo-referenced databases. Location…

Computer Vision and Pattern Recognition · Computer Science 2020-06-28 Li Weng , Valerie Gouet-Brunet , Bahman Soheilian

Spatial transcriptomics (ST) provides high-resolution pathological images and whole-transcriptomic expression profiles at individual spots across whole-slide scales. This setting makes it an ideal data source to develop multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Yuxiang Lin , Ling Luo , Ying Chen , Xushi Zhang , Zihui Wang , Wenxian Yang , Mengsha Tong , Rongshan Yu

Environmental and climate processes are often distributed over large space-time domains. Their complexity and the amount of available data make modelling and analysis a challenging task. Statistical modelling of environment and climate data…

Methodology · Statistics 2019-10-02 Behnaz Pirzamanbein

Statistical and mathematical modeling are crucial to describe, interpret, compare and predict the behavior of complex biological systems including the organization of hematopoietic stem and progenitor cells in the bone marrow environment.…

Quantitative Methods · Quantitative Biology 2018-09-07 Walter de Back , Thomas Zerjatke , Ingo Roeder

Spatial autocorrelation and spatial heterogeneity widely exist in spatial data, which make the traditional machine learning model perform badly. Spatial domain generalization is a spatial extension of domain generalization, which can…

Machine Learning · Computer Science 2022-12-29 Dazhou Yu , Guangji Bai , Yun Li , Liang Zhao

Spatiotemporal graph represents a crucial data structure where the nodes and edges are embedded in a geometric space and can evolve dynamically over time. Nowadays, spatiotemporal graph data is becoming increasingly popular and important,…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Hengning Cao , Yanfang Ye , Liang Zhao

Spatiotemporal data mining aims to discover interesting, useful but non-trivial patterns in big spatial and spatiotemporal data. They are used in various application domains such as public safety, ecology, epidemiology, earth science, etc.…

Databases · Computer Science 2022-06-28 Arun Sharma , Zhe Jiang , Shashi Shekhar

Understanding functional organization of genetic information is a major challenge in modern biology. Following the initial publication of the human genome sequence in 2001, advances in high-throughput measurement technologies and efficient…

Machine Learning · Statistics 2011-03-01 Leo Lahti

This gem describes a standard method for generating synthetic spatial data that can be used in benchmarking and scalability tests. The goal is to improve the reproducibility and increase the trust in experiments on synthetic data by using…

Databases · Computer Science 2021-09-28 Tin Vu , Sara Migliorini , Ahmed Eldawy , Alberto Belussi

Biological systems commonly exhibit complex spatiotemporal patterns whose underlying generative mechanisms pose a significant analytical challenge. Traditional approaches to spatiodynamic inference rely on dimensionality reduction through…

Quantitative Methods · Quantitative Biology 2025-08-01 Jun Won Park , Kangyu Zhao , Sanket Rane

Accurate segmentation of topological tubular structures, such as blood vessels and roads, is crucial in various fields, ensuring accuracy and efficiency in downstream tasks. However, many factors complicate the task, including thin local…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Yaolei Qi , Yuting He , Xiaoming Qi , Yuan Zhang , Guanyu Yang