Related papers: Diamond-based Detection Systems for Accurate Pulse…
Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-pulse dose monitoring and a real-time dose-based control system…
FLASH radiotherapy necessitates the development of advanced Quality Assurance methods and detectors for accurate and online monitoring of the radiation field. This study introduces enhanced time-resolution detection systems and methods…
Background: FLASH radiotherapy is a treatment regime that delivers therapeutic dose to tumors at an ultra-high dose rate while maintaining adequate normal tissue sparing. However, a comprehensive understanding of the underlying mechanisms,…
Purpose: A diode EDGE Detector with a newly designed electrometer has been characterized for use in an UHDR electron beam and demonstrated appropriateness for UHDR FLASH radiotherapy dosimetry. Methods: Dose linearity, mean dose rate, and…
While spatial dose conformity delivered to a target volume has been pushed to its practical limits with advanced treatment planning and delivery, investigations in novel temporal dose delivery are unfolding new mechanisms. Recent advances…
We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and cell-culture FLASH radiobiology experiments. UHDR electron beams were controlled by a…
Purpose: In this study, procedures were developed to achieve efficient reversible conversion of a clinical linear accelerator (LINAC) and deliver electron FLASH (eFLASH) or conventional beams to the treatment room isocenter. Material &…
FLASH-RT has proven beneficial in preclinical studies. However, the lack of accurate real time 2D dosimetry is a limiting factor. In this work, an innovative solution for 2D real time dosimetry in UHDR electron beams is presented. The…
Diamond sensors (DS) are widely used as solid-state particle detectors, beam loss monitors, and dosimeters in high-radiation environments, e.g., particle colliders. We have calibrated our DS with steady $\beta$- and X-radiation, spanning a…
High energy radiations are nowadays cornerstone in scientific, medical and industrial imaging and cancer therapy. However, their detection and dosimetry are restricted to systems of modest compactness that are not compatible with endoscopy.…
A liquid isooctane (C$_{8}$H$_{18}$) filled ionization linear array for radiotherapy quality assurance has been designed, built and tested. The detector consists of 128 pixels, each of them with an area of 1.7 mm $\times$ 1.7 mm and a gap…
Irradiations at Ultra High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radio-therapy with reduced harm to normal tissues. This…
For the characterization of the 10 mA ion beam delivered by the new High Current Linac at GSI, sophisticated, mainly non-intersepting diagnostic devices were developed. Besides the general set-up of a versatile test bench, we discuss in…
This article introduces a design of a Low Noise Amplifier (LNA), for the field of diamond particle detectors. This amplifier is described from simulation to measurements, which include pulses from {\alpha} particles detection. In hadron…
Single-crystal synthetic diamond sensors have been widely used in radiation dosimetry and beam diagnostics. The foreseen harsh radiation environment in electron-positron colliders at the luminosity frontier requires a thorough investigation…
Artificially-grown diamond crystals have unique properties that make them suitable as solid-state particle detectors and dosimeters in high-radiation environments. We have been using sensors based on single-crystal diamond grown by chemical…
Objective: While FLASH radiotherapy is recognized for short-term normal tissue sparing, its durability in late-responding organs remains uncertain, limiting clinical adoption. With its clinical importance and steep dose-response, the spinal…
Currently planned and constructed terrestrial detectors for gravitational waves and dark matter based on differential light-pulse atom interferometry are designed around three primary strategies to enhance their sensitivity: (i)…
This paper describes the design and testing results of an 8 channels preamplifier-discriminator circuit based on a resistive feedback Transimpedance Amplifier architecture and a Leading-Edge Discriminator stage for fast high-accuracy time…
Background: Scintillation dosimetry has promising qualities for ultra-high dose rate (UHDR) radiotherapy (RT), but no system has shown compatibility with mean dose rates ($\bar{DR}$) above 100 Gy/s and doses per pulse ($D_p$) exceeding 1.5…