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Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling…

Fluid Dynamics · Physics 2018-06-13 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

Microorganisms develop coordinated beating patterns on surfaces lined with cilia known as metachronal waves. For a chain of cilia attached to a flat ciliate, it has been shown that hydrodynamic interactions alone can lead the system to…

Fluid Dynamics · Physics 2016-03-23 Babak Nasouri , Gwynn J. Elfring

Motile cilia beat in an asymmetric fashion in order to propel the surrounding fluid. When many cilia are located on a surface, their beating can synchronise such that their phases form metachronal waves. Here, we computationally study a…

Soft Condensed Matter · Physics 2023-09-29 David J. Hickey , Ramin Golestanian , Andrej Vilfan

Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thousands of individual cilia that beat in a striking metachronal…

Soft Condensed Matter · Physics 2022-11-30 Anup Kanale , Feng Ling , Hanliang Guo , Sebastian Fuerthauer , Eva Kanso

Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the action of internal molecular motors and are typically found in dense arrays. These active filaments coordinate their beating to generate…

Soft Condensed Matter · Physics 2022-01-28 Brato Chakrabarti , Sebastian Fürthauer , Michael J. Shelley

Carpets of actively bending cilia represent arrays of biological oscillators that can exhibit self-organized metachronal synchronization in the form of traveling waves of cilia phase. This metachronal coordination supposedly enhances fluid…

Biological Physics · Physics 2022-01-11 Anton Solovev , Benjamin M. Friedrich

Cilia are motile biological appendages that are driven to bend by internal shear stresses between tubulin filaments. A continuum model of ciliary material is constructed that incorporates the essential ciliary constraints: (1)…

Soft Condensed Matter · Physics 2013-05-29 Mark A. Peterson

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

Soft Condensed Matter · Physics 2016-04-20 Nicolas Bruot , Pietro Cicuta

Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between different synchronization modes in the same cell type. Here, we…

Fluid Dynamics · Physics 2018-02-14 Hanliang Guo , Lisa Fauci , Michael Shelley , Eva Kanso

Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…

Tissues and Organs · Quantitative Biology 2020-01-13 Pietro Cicuta

In a variety of biological processes, eukaryotic cells use cilia to transport flow. Although cilia have a remarkably conserved internal molecular structure, experimental observations report very diverse kinematics. To address this…

Biological Physics · Physics 2012-07-19 Christophe Eloy , Eric Lauga

Non-equilibrium processes which convert chemical energy into mechanical motion enable the motility of organisms. Bundles of inextensible filaments driven by energy transduction of molecular motors form essential components of micron-scale…

Soft Condensed Matter · Physics 2013-06-13 Abhrajit Laskar , Rajeev Singh , Somdeb Ghose , Gayathri Jayaraman , P. B. Sunil Kumar , R. Adhikari

Enhanced colloidal transport beyond the limit imposed by diffusion is usually achieved through external fields. Here, we demonstrate the ballistic transport of a colloidal sphere using internal sources of energy provided by an attached…

Soft Condensed Matter · Physics 2017-01-12 Raj Kumar Manna , P. B. Sunil Kumar , R. Adhikari

Large groups of active cilia collectively beat in a fluid medium as metachronal waves, essential for some microorganisms motility and for flow generation in mucociliary clearance. Several models can predict the emergence of metachronal…

Soft Condensed Matter · Physics 2024-05-08 Supravat Dey , Gladys Massiera , Estelle Pitard

We study a slender filament beating in a viscous fluid with novel curvature-dependent bending stiffness. Our numerical and experimental investigations reveal that such differential stiffness can sustain planar bending waves far along…

We calculate the hydrodynamic flow field generated far from a cilium which is attached to a surface and beats periodically. In the case of two beating cilia, hydrodynamic interactions can lead to synchronization of the cilia, which are…

Biological Physics · Physics 2007-05-23 Andrej Vilfan , Frank Julicher

Chiral active particles are able to draw energy from the environment to self-propel in the form of rotation. We describe an experimental arrangement wherein chiral objects, spinners, floating on the surface of a vibrated fluid rotate due to…

Soft Condensed Matter · Physics 2025-02-28 Nilgun Sungar , John Sharpe , Loic Ijzerman , Jack-William Barotta

Here we show that coupling to curvature has profound effects on collective motion in active systems, leading to patterns not observed in flat space. Biological examples of such active motion in curved environments are numerous: curvature…

Soft Condensed Matter · Physics 2015-03-05 Rastko Sknepnek , Silke Henkes

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

Fluid Dynamics · Physics 2011-08-30 Sebastien Michelin , Eric Lauga

Cells or bacteria carrying cilia on their surface show many striking features : alignment of cilia in an array, two-phase asymmetric beating for each cilium, coordination between cilia and existence of metachronal waves with a constant…

Biological Physics · Physics 2009-11-11 Boris Guirao , Jean-François Joanny
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