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We use a 3D computational model to study the fluid transport and mixing due to the beating of an infinite array of cilia. In accord with recent experiments, we observe two distinct regions: a fluid transport region above the cilia and a…

Fluid Dynamics · Physics 2014-03-24 Yang Ding , Janna Nawroth , Margaret McFall-Ngai , Eva Kanso

Cells are modeled with spherical grains connected each other. Each cell can shrink and swell by transporting its fluid content to other connected neighbor while still maintaining its density at constant value. As a spherical part of a cell…

Biological Physics · Physics 2014-02-27 Sparisoma Viridi , Nuning Nuraini

When a millimetric body is placed atop a vibrating liquid bath, the relative motion between the object and interface generates outward propagating waves with an associated momentum flux. Prior work has shown that isolated chiral objects,…

Soft Condensed Matter · Physics 2025-02-28 Jack-William Barotta , Giuseppe Pucci , Eli Silver , Alireza Hooshanginejad , Daniel M. Harris

Nature uses elongated shapes and filaments to build stable structures, generate motion, and allow complex geometric interactions. In this Review, we examine the role of biological filaments across different length scales. From the molecular…

Soft Condensed Matter · Physics 2025-07-25 Jan Cammann , Hannah Laeverenz-Schlogelhofer , Kirsty Y. Wan , Marco G. Mazza

On surfaces with many motile cilia, beats of the individual cilia coordinate to form metachronal waves. We present a theoretical framework that connects the dynamics of an individual cilium to the collective dynamics of a ciliary carpet via…

Soft Condensed Matter · Physics 2021-03-12 Fanlong Meng , Rachel R. Bennett , Nariya Uchida , Ramin Golestanian

Curvature plays a central organizational role in active polymer dynamics. Using large-scale Langevin-dynamics simulations, we study active semiflexible filaments confined to smooth curved surfaces and map how curvature, bending rigidity,…

Soft Condensed Matter · Physics 2026-02-18 Giulia Janzen , Euan D. Mackay , Rastko Sknepnek , D. A. Matoz-Fernandez

Cellular biology abound with filaments interacting through fluids, from intracellular microtubules, to rotating flagella and beating cilia. While previous work has demonstrated the complexity of capturing nonlocal hydrodynamic interactions…

Fluid Dynamics · Physics 2016-12-21 Yi Man , Lyndon Koens , Eric Lauga

Motor proteins drive persistent motion and self-organisation of cytoskeletal filaments. However, state-of-the-art microscopy techniques and continuum modelling approaches focus on large length and time scales. Here, we perform…

Soft Condensed Matter · Physics 2024-06-03 Gerrit Vliegenthart , Arvind Ravichandran , Marisol Ripoll , Thorsten Auth , Gerhard Gompper

Flexible filaments moving in viscous fluids are ubiquitous in the natural microscopic world. For example, the swimming of bacteria and spermatozoa as well as important physiological functions at organ-level, such as the cilia-induced motion…

Soft Condensed Matter · Physics 2019-06-05 Panayiota Katsamba , Eric Lauga

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

By taking into account the hydrodynamic interactions in a one dimensional array of model cilia attached to a no-slip cylinderical surface, we investigate their synchronized motion. We show, how does the emergence of metachronal waves depend…

Biological Physics · Physics 2017-05-31 Aref Ghorbani , Ali Najafi

Active filaments, such as microtubules with attached cargo-carrying motor proteins, are important dynamic structures for fluid transport in and around living cells. The mathematical models of active filaments appearing in the literature…

Fluid Dynamics · Physics 2025-08-19 Ilteber R. Ozdemir , Bethany Clarke , Yongyun Hwang , Eric E. Keaveny

Despite recent advances in artificial cilia technologies, the application of metachrony, which is the collective wavelike motion by cilia moving out-of-phase, has been severely hampered by difficulties in controlling densely packed…

Cellular locomotion often involves the motion of thin, elastic filaments, such as cilia and flagella, in viscous environments. The manuscript serves as a general introduction to the topic of modelling microscale elastohydrodynamics. We…

Soft Condensed Matter · Physics 2024-10-15 Maciej Lisicki

Active matter consists of self-propelled elements exhibits fascinating collective motions ranging from biological to artificial systems. Among wide varieties of active matter systems, reconstituted bio-filaments moving on molecular motor…

Soft Condensed Matter · Physics 2020-03-25 Sakurako Tanida , Ken'ya Furuta , Kaori Nishikawa , Tetsuya Hiraiwa , Hiroaki Kojima , Kazuhiro Oiwa , Masaki Sano

Contact inhibition plays a crucial role in the motility of cells, the process of wound healing, and the formation of tumors. By mimicking the mechanical motion of calls crawling on a substrate using a pseudopod, we constructed a minimal…

Soft Condensed Matter · Physics 2016-11-28 Simon Kaspar Schnyder , Yuki Tanaka , John Jairo Molina , Ryoichi Yamamoto

Natural cilia are hair-like microtubule-based structures that are able to move fluid at low Reynolds number through asymmetric motion. In this paper we follow a biomimetic approach to design artificial cilia lining the inner surface of…

Dynamic organization of the cytoskeletal filaments and rod-like proteins in the cell membrane and other biological interfaces occurs in many cellular processes. Previous modeling studies have considered the dynamics of a single rod on fluid…

Fluid Dynamics · Physics 2022-06-17 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Filamentous cyanobacteria can show fascinating examples of nonequilibrium self-organization, which however are not well-understood from a physical perspective. We investigate the motility and collective organization of colonies of these…

Soft Condensed Matter · Physics 2023-10-20 Mixon K. Faluweki , Jan Cammann , Marco G. Mazza , Lucas Goehring

Synchronization plays a crucial role in the dynamics of living organisms, from fireflies flashing in unison to pacemaker cells that jointly generate heartbeats. Uncovering the mechanism behind these phenomena requires an understanding of…

Adaptation and Self-Organizing Systems · Physics 2024-05-16 Aleksandre Japaridze , Victor Struijk , Kushal Swamy , Irek Roslon , Oriel Shoshani , Cees Dekker , Farbod Alijani