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Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Medical image segmentation modeling is a high-stakes task where understanding of uncertainty is crucial for addressing visual ambiguity. Prior work has developed segmentation models utilizing probabilistic or generative mechanisms to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Andre Ye , Quan Ze Chen , Amy Zhang

Deep learning has achieved significant breakthroughs in medical imaging, but these advancements are often dependent on large, well-annotated datasets. However, obtaining such datasets poses a significant challenge, as it requires…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Siteng Ma , Honghui Du , Yu An , Jing Wang , Qinqin Wang , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Guoping Xu , Jayaram K. Udupa , Jax Luo , Songlin Zhao , Yajun Yu , Scott B. Raymond , Hao Peng , Lipeng Ning , Yogesh Rathi , Wei Liu , You Zhang

Segmentation of pathological images is essential for accurate disease diagnosis. The quality of manual labels plays a critical role in segmentation accuracy; yet, in practice, the labels between pathologists could be inconsistent, thus…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Li Xiao , Yinhao Li , Luxi Qv , Xinxia Tian , Yijie Peng , S. Kevin Zhou

Collecting annotations from multiple independent sources could mitigate the impact of potential noises and biases from a single source, which is a common practice in medical image segmentation. Learning segmentation networks from…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Yifeng Wang , Luyang Luo , Mingxiang Wu , Qiong Wang , Hao Chen

Identifying and handling label errors can significantly enhance the accuracy of supervised machine learning models. Recent approaches for identifying label errors demonstrate that a low self-confidence of models with respect to a certain…

Machine Learning · Computer Science 2024-05-17 Johannes Jakubik , Michael Vössing , Manil Maskey , Christopher Wölfle , Gerhard Satzger

Segment anything model (SAM) has emerged as the leading approach for zero-shot learning in segmentation tasks, offering the advantage of avoiding pixel-wise annotations. It is particularly appealing in medical image segmentation, where the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Ziyi Huang , Hongshan Liu , Haofeng Zhang , Xueshen Li , Haozhe Liu , Fuyong Xing , Andrew Laine , Elsa Angelini , Christine Hendon , Yu Gan

Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Two of the most common tasks in medical imaging are classification and segmentation. Either task requires labeled data annotated by experts, which is scarce and expensive to collect. Annotating data for segmentation is generally considered…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Ozan Ciga , Anne L. Martel

Most image segmentation algorithms are trained on binary masks formulated as a classification task per pixel. However, in applications such as medical imaging, this "black-and-white" approach is too constraining because the contrast between…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Charley Gros , Andreanne Lemay , Julien Cohen-Adad

Machine learning models for medical images can help physicians diagnose and manage diseases. However, due to the fact that medical image annotation requires a great deal of manpower and expertise, as well as the fact that clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Can Li , Sheng Shao , Junyi Qu , Shuchao Pang , Mehmet A. Orgun

When applying a Deep Learning model to medical images, it is crucial to estimate the model uncertainty. Voxel-wise uncertainty is a useful visual marker for human experts and could be used to improve the model's voxel-wise output, such as…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

In the domain of medical imaging, many supervised learning based methods for segmentation face several challenges such as high variability in annotations from multiple experts, paucity of labelled data and class imbalanced datasets. These…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Soumick Chatterjee , Franziska Gaidzik , Alessandro Sciarra , Hendrik Mattern , Gábor Janiga , Oliver Speck , Andreas Nürnberger , Sahani Pathiraja

This paper explores the use of a soft ground-truth mask ("soft mask'') to train a Fully Convolutional Neural Network (FCNN) for segmentation of Multiple Sclerosis (MS) lesions. Detection and segmentation of MS lesions is a complex task…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan

This paper presents an automatic algorithm for the segmentation of areas affected by an acute stroke on the non-contrast computed tomography brain images. The proposed algorithm is designed for learning in a weakly supervised scenario when…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Anna Dobshik , Andrey Tulupov , Vladimir Berikov
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