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Related papers: Deep learning tackles single-cell analysis A surve…

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Deep-Learning(DL) applications have been widely employed to assist in various tasks. They are constructed based on a data-driven programming paradigm that is different from conventional software applications. Given the increasing popularity…

Software Engineering · Computer Science 2019-10-09 Xufan Zhang , Yilin Yang , Yang Feng , Zhenyu Chen

The ability to measure the transcriptomes of single cells has only been feasible for a few years, and is becoming an extremely popular assay. While many types of analysis and questions can be answered using single cell RNA-sequencing, a…

Genomics · Quantitative Biology 2017-08-09 Valentine Svensson , Roser Vento-Tormo , Sarah A Teichmann

Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells, which has given us insights into cell-cell communication, cell differentiation, and differential gene expression. However, analyzing scRNA-seq data is a…

Machine Learning · Computer Science 2023-06-27 Yuta Hozumi , Gu-Wei Wei

Motivation: Single cell transcriptome sequencing (scRNA-Seq) has become a revolutionary tool to study cellular and molecular processes at single cell resolution. Among existing technologies, the recently developed droplet-based platform…

Machine Learning · Statistics 2017-04-10 Zhe Sun , Ting Wang , Ke Deng , Xiao-Feng Wang , Robert Lafyatis , Ying Ding , Ming Hu , Wei Chen

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

Genomics · Quantitative Biology 2025-11-19 Yue Ling , Peiqi Zhang , Zhenyi Zhang , Peijie Zhou

Deep learning has empowered analysis for single-cell sequencing data in many ways and has generated deep understanding about a range of complex cellular systems. As the booming single-cell sequencing technologies brings the surge of high…

Genomics · Quantitative Biology 2021-04-27 Yang Xu , Andrew Jeremiah Strick

The pervasive nature of software vulnerabilities has emerged as a primary factor for the surge in cyberattacks. Traditional vulnerability detection methods, including rule-based, signature-based, manual review, static, and dynamic analysis,…

Software Engineering · Computer Science 2025-03-07 Md Nizam Uddin , Yihe Zhang , Xiali Hei

Single-cell RNA sequencing (scRNA-seq) has made significant strides in unraveling the intricate cellular diversity within complex tissues. This is particularly critical in the brain, presenting a greater diversity of cell types than other…

Machine Learning · Computer Science 2023-10-05 Gyutaek Oh , Baekgyu Choi , Inkyung Jung , Jong Chul Ye

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

Deep Neural Networks (DNNs) are becoming an important tool in modern computing applications. Accelerating their training is a major challenge and techniques range from distributed algorithms to low-level circuit design. In this survey, we…

Machine Learning · Computer Science 2018-09-18 Tal Ben-Nun , Torsten Hoefler

Deep learning, a rebranding of deep neural network research works, has achieved a remarkable success in recent years. With multiple hidden layers, deep learning models aim at computing the hierarchical feature representations of the…

Neural and Evolutionary Computing · Computer Science 2018-06-06 Jiawei Zhang , Limeng Cui , Fisher B. Gouza

Sequence labeling (SL) is a fundamental research problem encompassing a variety of tasks, e.g., part-of-speech (POS) tagging, named entity recognition (NER), text chunking, etc. Though prevalent and effective in many downstream applications…

Computation and Language · Computer Science 2020-11-16 Zhiyong He , Zanbo Wang , Wei Wei , Shanshan Feng , Xianling Mao , Sheng Jiang

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

Deep learning (DL) along with never-ending advancements in computational processing and cloud technologies have bestowed us powerful analyzing tools and techniques in the past decade and enabled us to use and apply them in various fields of…

Machine Learning · Computer Science 2023-02-23 Farzan Shenavarmasouleh , Farid Ghareh Mohammadi , Khaled M. Rasheed , Hamid R. Arabnia

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

Single-cell RNA sequencing (scRNA-seq) is important to transcriptomic analysis of gene expression. Recently, deep learning has facilitated the analysis of high-dimensional single-cell data. Unfortunately, deep learning models may leak…

Machine Learning · Computer Science 2024-05-14 Huifa Li , Jie Fu , Zhili Chen , Xiaomin Yang , Haitao Liu , Xinpeng Ling

Background: Small interfering RNA (siRNA) is a promising therapeutic agent due to its ability to silence disease-related genes via RNA interference. While traditional machine learning and early deep learning methods have made progress in…

Biomolecules · Quantitative Biology 2025-03-07 Wangdan Liao , Weidong Wang

Deep learning (DL), a new-generation of artificial neural network research, has transformed industries, daily lives and various scientific disciplines in recent years. DL represents significant progress in the ability of neural networks to…

Machine Learning · Statistics 2018-09-05 Chaopeng Shen

With the growth of artificial intelligence (AI), there has been an increase in the adoption of computer vision and deep learning (DL) techniques for the evaluation of microscopy images and movies. This adoption has not only addressed…

Quantitative Methods · Quantitative Biology 2023-07-21 Binghao Chai , Christoforos Efstathiou , Haoran Yue , Viji M. Draviam

The plethora of single-cell multi-omics data is getting treatment with deep learning, a revolutionary method in artificial intelligence, which has been increasingly expanding its reign over the bioscience frontiers.

Other Quantitative Biology · Quantitative Biology 2019-03-12 A. K. M. Azad , Fatemeh Vafaee