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Related papers: Can Language Models be Biomedical Knowledge Bases?

200 papers

Previous literatures show that pre-trained masked language models (MLMs) such as BERT can achieve competitive factual knowledge extraction performance on some datasets, indicating that MLMs can potentially be a reliable knowledge source. In…

Computation and Language · Computer Science 2021-06-18 Boxi Cao , Hongyu Lin , Xianpei Han , Le Sun , Lingyong Yan , Meng Liao , Tong Xue , Jin Xu

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Pre-trained language models (LMs) have recently gained attention for their potential as an alternative to (or proxy for) explicit knowledge bases (KBs). In this position paper, we examine this hypothesis, identify strengths and limitations…

Computation and Language · Computer Science 2021-10-18 Simon Razniewski , Andrew Yates , Nora Kassner , Gerhard Weikum

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has…

Computation and Language · Computer Science 2021-09-22 Rahul Nadkarni , David Wadden , Iz Beltagy , Noah A. Smith , Hannaneh Hajishirzi , Tom Hope

Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

Computation and Language · Computer Science 2023-05-09 Deepak Gupta , Dina Demner-Fushman

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

Objective: This study investigates the potential of Large Language Models (LLMs) as an alternative to human expert elicitation for extracting structured causal knowledge and facilitating causal modeling in biometric and healthcare…

Artificial Intelligence · Computer Science 2025-04-15 Olha Shaposhnyk , Daria Zahorska , Svetlana Yanushkevich

Large Language Models (LLMs) are increasingly explored as knowledge bases (KBs), yet current evaluation methods focus too narrowly on knowledge retention, overlooking other crucial criteria for reliable performance. In this work, we rethink…

Computation and Language · Computer Science 2024-12-17 Danna Zheng , Mirella Lapata , Jeff Z. Pan

Language models (LMs) capabilities have grown with a fast pace over the past decade leading researchers in various disciplines, such as biomedical research, to increasingly explore the utility of LMs in their day-to-day applications. Domain…

Computation and Language · Computer Science 2025-06-16 Aman Sinha , Bogdan-Valentin Popescu , Xavier Coubez , Marianne Clausel , Mathieu Constant

Large language models (LLMs) have broad medical knowledge and can reason about medical information across many domains, holding promising potential for diverse medical applications in the near future. In this study, we demonstrate a…

As language models (LMs) become integral to fields like healthcare, law, and journalism, their ability to differentiate between fact, belief, and knowledge is essential for reliable decision-making. Failure to grasp these distinctions can…

Computation and Language · Computer Science 2024-10-29 Mirac Suzgun , Tayfun Gur , Federico Bianchi , Daniel E. Ho , Thomas Icard , Dan Jurafsky , James Zou

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

In this paper, we address reasoning tasks from open vocabulary Knowledge Bases (openKBs) using state-of-the-art Neural Language Models (NLMs) with applications in scientific literature. For this purpose, self-attention based NLMs are…

The unprecedented performance of large language models (LLMs) necessitates improvements in evaluations. Rather than merely exploring the breadth of LLM abilities, we believe meticulous and thoughtful designs are essential to thorough,…

Large Language Models (LLMs) increasingly support applications in a wide range of domains, some with potential high societal impact such as biomedicine, yet their reliability in realistic use cases is under-researched. In this work we…

Large Language Models (LLMs) have emerged as highly capable systems and are increasingly being integrated into various uses. However, the rapid pace of their deployment has outpaced a comprehensive understanding of their internal mechanisms…

Computation and Language · Computer Science 2025-10-27 Gabriele Prato , Jerry Huang , Prasanna Parthasarathi , Shagun Sodhani , Sarath Chandar

Large language models (LLMs) provide capabilities far beyond sentence completion, including question answering, summarization, and natural-language inference. While many of these capabilities have potential application to cognitive systems,…

Artificial Intelligence · Computer Science 2023-10-12 James R. Kirk , Robert E. Wray , John E. Laird

Most biomedical pretrained language models are monolingual and cannot handle the growing cross-lingual requirements. The scarcity of non-English domain corpora, not to mention parallel data, poses a significant hurdle in training…

Computation and Language · Computer Science 2023-11-21 Lei Geng , Xu Yan , Ziqiang Cao , Juntao Li , Wenjie Li , Sujian Li , Xinjie Zhou , Yang Yang , Jun Zhang