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Bayesian optimization (BO) algorithms try to optimize an unknown function that is expensive to evaluate using minimum number of evaluations/experiments. Most of the proposed algorithms in BO are sequential, where only one experiment is…
Bayesian optimization (BO) is a widely-used sequential method for zeroth-order optimization of complex and expensive-to-compute black-box functions. The existing BO methods assume that the function evaluation (feedback) is available to the…
Brain-computer interface (BCI) is the technology that enables the communication between humans and devices by reflecting status and intentions of humans. When conducting imagined speech, the users imagine the pronunciation as if actually…
Identification of optimal dose combinations in early phase dose-finding trials is challenging, due to the trade-off between precisely estimating the many parameters required to flexibly model the possibly non-monotonic dose-response…
Brain-computer interfaces (BCIs) promise to extend human movement capabilities by enabling direct neural control of supernumerary effectors, yet integrating augmented commands with multiple degrees of freedom without disrupting natural…
Research on transcranial magnetic stimulation (TMS) combined with encephalography feedback (EEG-TMS) has shown that the phase of the sensorimotor mu rhythm is predictive of corticospinal excitability. Thus, if the subject-specific optimal…
Modeling invasive neural spike data is fundamental to advancing high-performance brain-computer interfaces (BCIs). However, existing approaches face critical challenges, including limited-scale heterogeneous data, cross-domain distribution…
An asynchronous Brain--Computer Interface (BCI) based on imagined speech is a tool that allows to control an external device or to emit a message at the moment the user desires to by decoding EEG signals of imagined speech. In order to…
Brain computer interface (BCI) provides promising applications in neuroprosthesis and neurorehabilitation by controlling computers and robotic devices based on the patient's intentions. Here, we have developed a novel BCI platform that…
An Event-Related Potential (ERP)-based Brain-Computer Interface (BCI) Speller System assists people with disabilities to communicate by decoding electroencephalogram (EEG) signals. A P300-ERP embedded in EEG signals arises in response to a…
We recently reported the existence of fluctuations in neural signals that may permit neurons to code multiple simultaneous stimuli sequentially across time. This required deploying a novel statistical approach to permit investigation of…
This dissertation covers a single-processor approach to the speech processing pipeline of bilateral Cochlear Implants (CIs). The use of only a single processor to provide binaural stimulation signals overcomes the synchronization problem,…
Experimental (design) optimization is a key driver in designing and discovering new products and processes. Bayesian Optimization (BO) is an effective tool for optimizing expensive and black-box experimental design processes. While Bayesian…
Auditory front-end is an integral part of a spiking neural network (SNN) when performing auditory cognitive tasks. It encodes the temporal dynamic stimulus, such as speech and audio, into an efficient, effective and reconstructable spike…
Early phase, personalized dose-finding trials for combination therapies seek to identify patient-specific optimal biological dose (OBD) combinations, which are defined as safe dose combinations which maximize therapeutic benefit for a…
Simulation-based inference (SBI) is a method to perform inference on a variety of complex scientific models with challenging inference (inverse) problems. Bayesian Optimal Experimental Design (BOED) aims to efficiently use experimental…
The paper presents results from a psychophysical study conducted to optimize vibrotactile stimuli delivered to subject finger tips in order to evoke the somatosensory responses to be utilized next in a haptic brain computer interface (hBCI)…
A brain-computer interface (BCI) can't be effectively used since electroencephalography (EEG) varies between and within subjects. BCI systems require calibration steps to adjust the model to subject-specific data. It is widely acknowledged…
A brain-computer interface (BCI) based on the motor imagery (MI) paradigm translates one's motor intention into a control signal by classifying the Electroencephalogram (EEG) signal of different tasks. However, most existing systems either…
Bayesian optimization has emerged as a highly effective tool for the safe online optimization of systems, due to its high sample efficiency and noise robustness. To further enhance its efficiency, reduced physical models of the system can…