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Recently, DNA storage has surfaced as a promising alternative for data storage, presenting notable benefits in terms of storage capacity, cost-effectiveness in maintenance, and the capability for parallel replication. Mathematically, the…

Information Theory · Computer Science 2024-01-31 Yi Lu , Yun Ma , Chenghao Li , Xin Zhang , Guangxiang Si

Motivated by DNA-based data storage, we investigate a system where digital information is stored in an unordered set of several vectors over a finite alphabet. Each vector begins with a unique index that represents its position in the whole…

Information Theory · Computer Science 2019-01-23 Andreas Lenz , Paul H. Siegel , Antonia Wachter-Zeh , Eitan Yaakobi

Density reconstruction from X-ray projections is an important problem in radiography with key applications in scientific and industrial X-ray computed tomography (CT). Often, such projections are corrupted by unknown sources of noise and…

Image and Video Processing · Electrical Eng. & Systems 2026-02-26 Siddhant Gautam , Marc L. Klasky , Balasubramanya T. Nadiga , Trevor Wilcox , Gary Salazar , Saiprasad Ravishankar

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Precise load forecasting in buildings could increase the bill savings potential and facilitate optimized strategies for power generation planning. With the rapid evolution of computer science, data-driven techniques, in particular the Deep…

Machine Learning · Computer Science 2023-01-30 Menna Nawar , Moustafa Shomer , Samy Faddel , Huangjie Gong

Transformer is a deep neural network that employs a self-attention mechanism to comprehend the contextual relationships within sequential data. Unlike conventional neural networks or updated versions of Recurrent Neural Networks (RNNs) such…

Machine Learning · Computer Science 2023-06-14 Saidul Islam , Hanae Elmekki , Ahmed Elsebai , Jamal Bentahar , Najat Drawel , Gaith Rjoub , Witold Pedrycz

We study the amount of reliable information that can be stored in a DNA-based storage system with noisy sequencing, where each codeword is composed of short DNA molecules. We analyze a concatenated coding scheme, where the outer code is…

Information Theory · Computer Science 2026-05-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

Deep neural networks (DNN) are growing in capability and applicability. Their effectiveness has led to their use in safety critical and autonomous systems, yet there is a dearth of cost-effective methods available for reasoning about the…

Neural and Evolutionary Computing · Computer Science 2019-08-22 David Shriver , Dong Xu , Sebastian Elbaum , Matthew B. Dwyer

In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

Information Theory · Computer Science 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

Convolutional Neural Network (CNN) has gained state-of-the-art results in many pattern recognition and computer vision tasks. However, most of the CNN structures are manually designed by experienced researchers. Therefore, auto- matically…

Neural and Evolutionary Computing · Computer Science 2018-10-26 Guoqiang Zhong , Tao Li , Wenxue Liu , Yang Chen

In this paper, we consider the outer channel for DNA-based data storage. When transmitting over the outer channel, each DNA string is treated as a unit/symbol that would be either correctly received, or erased, or corrupted by uniformly…

Information Theory · Computer Science 2025-09-23 Xuan He , Yi Ding , Kui Cai , Guanghui Song , Bin Dai , Xiaohu Tang

Current neural network (NN) models can learn patterns from data points with historical dependence. Specifically, in natural language processing (NLP), sequential learning has transitioned from recurrence-based architectures to…

Machine Learning · Computer Science 2025-04-08 Muhammed Adil Yatkin , Mihkel Korgesaar , Jani Romanoff , Umit Islak , Hasan Kurban

Most DNA sequencing technologies are based on the shotgun paradigm: many short reads are obtained from random unknown locations in the DNA sequence. A fundamental question, studied in arXiv:1203.6233, is what read length and coverage depth…

Information Theory · Computer Science 2022-02-09 Aditya Narayan Ravi , Alireza Vahid , Ilan Shomorony

Transformers evaluated in a single, fixed-depth pass are provably limited in expressive power to the constant-depth circuit class TC0. Running a Transformer autoregressively removes that ceiling -- first in next-token prediction and, more…

Machine Learning · Computer Science 2025-07-21 Mrinal Mathur , Mike Doan , Barak Pearlmutter , Sergey Plis

High read depth can be used to assemble short sequence repeats. The existing genome assemblers fail in repetitive regions of longer than average read. I propose a new algorithm for a DNA assembly which uses the relative frequency of reads…

Genomics · Quantitative Biology 2015-01-08 Robert M. Nowak

Deep learning employs multi-layer neural networks trained via the backpropagation algorithm. This approach has achieved success across many domains and relies on adaptive gradient methods such as the Adam optimizer. Sequence modeling…

Machine Learning · Computer Science 2025-07-16 Esmail Gumaan

The ability to reconstruct fine-grained network session data, including individual packets, from coarse-grained feature vectors is crucial for improving network security models. However, the large-scale collection and storage of raw network…

Machine Learning · Computer Science 2025-04-16 Mark Cheung , Sridhar Venkatesan

This thesis focuses on representation learning for sequence data over time or space, aiming to improve downstream sequence prediction tasks by using the learned representations. Supervised learning has been the most dominant approach for…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-02 Qingming Tang

Biological sequence analysis relies on the ability to denoise the imprecise output of sequencing platforms. We consider a common setting where a short sequence is read out repeatedly using a high-throughput long-read platform to generate…

Genomics · Quantitative Biology 2023-09-06 Nathan Ng , Ji Won Park , Jae Hyeon Lee , Ryan Lewis Kelly , Stephen Ra , Kyunghyun Cho

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren
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