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Read mapping is a fundamental, yet computationally-expensive step in many genomics applications. It is used to identify potential matches and differences between fragments (called reads) of a sequenced genome and an already known genome…

Synthetic DNA can in principle be used for the archival storage of arbitrary data. Because errors are introduced during DNA synthesis, storage, and sequencing, an error-correcting code (ECC) is necessary for error-free recovery of the data.…

Quantitative Methods · Quantitative Biology 2018-12-05 William H. Press , John A. Hawkins

Motivated by polymer-based data-storage platforms that use chains of binary synthetic polymers as the recording media and read the content via tandem mass spectrometers, we propose a new family of codes that allows for both unique string…

Information Theory · Computer Science 2021-06-29 Srilakshmi Pattabiraman , Ryan Gabrys , Olgica Milenkovic

This paper presents an efficient speech enhancement (SE) approach that reuses a processing block repeatedly instead of conventional stacking. Rather than increasing the number of blocks for learning deep latent representations, repeating a…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-01 Jangyeon Kim , Ui-Hyeop Shin , Jaehyun Ko , Hyung-Min Park

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

The Transformer translation model is based on the multi-head attention mechanism, which can be parallelized easily. The multi-head attention network performs the scaled dot-product attention function in parallel, empowering the model by…

Computation and Language · Computer Science 2021-09-13 Hongfei Xu , Qiuhui Liu , Josef van Genabith , Deyi Xiong

Memory constraint of always-on devices is one of the major concerns when deploying speech processing models on these devices. While larger models trained with sufficiently large amount of data generally perform better, making them fit in…

Computation and Language · Computer Science 2024-01-09 Yiming Wang , Jinyu Li

Federated learning is an emerging research paradigm enabling collaborative training of machine learning models among different organizations while keeping data private at each institution. Despite recent progress, there remain fundamental…

Machine Learning · Computer Science 2022-04-15 Liangqiong Qu , Yuyin Zhou , Paul Pu Liang , Yingda Xia , Feifei Wang , Ehsan Adeli , Li Fei-Fei , Daniel Rubin

Addressing the resource waste caused by fixed computation paradigms in deep learning models under dynamic scenarios, this paper proposes a Transformer$^{-1}$ architecture based on the principle of deep adaptivity. This architecture achieves…

Machine Learning · Computer Science 2025-01-29 Lumen AI , Tengzhou No. 1 Middle School , Shihao Ji , Zihui Song , Fucheng Zhong , Jisen Jia , Zhaobo Wu , Zheyi Cao , Xu Tianhao

DNA has been considered a promising medium for storing digital information. As an essential step in the DNA-based data storage workflow, coding algorithms are responsible to implement functions including bit-to-base transcoding, error…

Emerging Technologies · Computer Science 2023-03-31 Haoling Zhang , Zhaojun Lan , Wenwei Zhang , Xun Xu , Zhi Ping , Yiwei Zhang , Yue Shen

We consider the problem of storing and retrieving information from synthetic DNA media. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on their collection of substrings…

Information Theory · Computer Science 2015-02-03 Han Mao Kiah , Gregory J. Puleo , Olgica Milenkovic

The sequence reconstruction problem for insertion/deletion channels has attracted significant attention owing to their applications recently in some emerging data storage systems, such as racetrack memories, DNA-based data storage. Our goal…

Information Theory · Computer Science 2026-04-24 Van Long Phuoc Pham , Yeow Meng Chee , Kui Cai , Van Khu Vu

Due to its high data density and longevity, DNA is considered a promising medium for satisfying ever-increasing data storage needs. However, the diversity of errors that occur in DNA sequences makes efficient error-correction a challenging…

Information Theory · Computer Science 2020-11-12 Yuanyuan Tang , Farzad Farnoud

We consider the reconstruction of a codeword from multiple noisy copies that are independently corrupted by insertions, deletions, and substitutions. This problem arises, for example, in DNA data storage. A common code construction uses a…

Information Theory · Computer Science 2025-11-04 Julian Streit , Franziska Weindel , Reinhard Heckel

Single-shot imaging with femtosecond X-ray lasers is a powerful measurement technique that can achieve both high spatial and temporal resolution. However, its accuracy has been severely limited by the difficulty of applying conventional…

Systematic techniques to improve quality of deep neural networks (DNNs) are critical given the increasing demand for practical applications including safety-critical ones. The key challenge comes from the little controllability in updating…

Machine Learning · Computer Science 2022-03-07 Shogo Tokui , Susumu Tokumoto , Akihito Yoshii , Fuyuki Ishikawa , Takao Nakagawa , Kazuki Munakata , Shinji Kikuchi

Stochastic microstructure reconstruction has become an indispensable part of computational materials science, but ongoing developments are specific to particular material systems. In this paper, we address this generality problem by…

Materials Science · Physics 2018-05-09 Xiaolin Li , Yichi Zhang , He Zhao , Craig Burkhart , L Catherine Brinson , Wei Chen

In the age of data revolution, a modern storage~or transmission system typically requires different levels of protection. For example, the coding technique used to fortify data in a modern storage system when the device is fresh cannot be…

Information Theory · Computer Science 2025-12-29 Doğukan Özbayrak , Ahmed Hareedy

Super-resolution reconstruction is aimed at generating images of high spatial resolution from low-resolution observations. State-of-the-art super-resolution techniques underpinned with deep learning allow for obtaining results of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Maciej Zyrek , Michal Kawulok

Synthetic polymer-based storage seems to be a particularly promising candidate that could help to cope with the ever-increasing demand for archival storage requirements. It involves designing molecules of distinct masses to represent the…

Information Theory · Computer Science 2026-04-02 Anisha Banerjee , Antonia Wachter-Zeh , Eitan Yaakobi
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