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Since the first recordings made of evoked action potentials it has become apparent that the responses of individual neurons to ongoing physiologically relevant input, are highly variable. This variability is manifested in non-stationary…

Neurons and Cognition · Quantitative Biology 2010-08-10 Avner Wallach , Danny Eytan , Asaf Gal , Christoph Zrenner , Ron Meir , Shimon Marom

Caenorhabditis elegans, a free-living soil nematode, propels itself by producing undulatory body motion and displays a rich variety of body shapes and trajectories during its locomotion in complex environments. Here we show that the complex…

We introduce SIM-CE, an advanced, user-friendly modeling and simulation environment in Simulink for performing multi-scale behavioral analysis of the nervous system of Caenorhabditis elegans (C. elegans). SIM-CE contains an implementation…

Neurons and Cognition · Quantitative Biology 2017-03-28 Ramin M. Hasani , Victoria Beneder , Magdalena Fuchs , David Lung , Radu Grosu

High density neurostimulation systems are coming to market to help spinal cord injury patients by stimulating and recording neuromuscular function. However, the parameter space that these systems have to explore is exceedingly large, and…

Signal Processing · Electrical Eng. & Systems 2021-12-06 Dhruv Pai , Mentor Kip Ludwig

High coherence visible and near-visible laser sources are centrally important to the operation of advanced position/navigation/timing systems as well as classical/quantum sensing systems. However, the complexity and size of these bench-top…

To establish the relationship between locomotory behavior and dynamics of neural circuits in the nematode C. elegans we combined molecular and theoretical approaches. In particular, we quantitatively analyzed the motion of C. elegans with…

Neurons and Cognition · Quantitative Biology 2008-06-10 Jan Karbowski , Gary Schindelman , Chris J. Cronin , Adeline Seah , Paul W. Sternberg

Caenorhabditis elegans (C. elegans) illustrated remarkable behavioral plasticities including complex non-associative and associative learning representations. Understanding the principles of such mechanisms presumably leads to constructive…

Neurons and Cognition · Quantitative Biology 2017-03-28 Ramin M. Hasani , Magdalena Fuchs , Victoria Beneder , Radu Grosu

Graph theoretical analyses of nervous systems usually omit the aspect of connection polarity, due to data insufficiency. The chemical synapse network of Caenorhabditis elegans is a well-reconstructed directed network, but the signs of its…

Molecular Networks · Quantitative Biology 2021-01-18 Bank G. Fenyves , Gabor S. Szilagyi , Zsolt Vassy , Csaba Soti , Peter Csermely

Free-living nematode Caenorhabditis elegans is a powerful genetic model, essential for investigations ranging from behavior to neuroscience to aging, and locomotion is a key observable used in these studies. However, despite the fact that…

Biological Physics · Physics 2019-01-18 Alejandro Bilbao , Amar K. Patel , Mizanur Rahman , Siva A. Vanapalli , Jerzy Blawzdziewicz

Walking animals, like stick insects, cockroaches or ants, demonstrate a fascinating range of locomotive abilities and complex behaviors. The locomotive behaviors can consist of a variety of walking patterns along with adaptation that allow…

Neural and Evolutionary Computing · Computer Science 2016-08-08 Sakyasingha Dasgupta , Dennis Goldschmidt , Florentin Wörgötter , Poramate Manoonpong

This paper develops a primal-dual dynamical system where the coefficients are designed in closed-loop way for solving a convex optimization problem with linear equality constraints. We first introduce a ``second-order primal" +…

Optimization and Control · Mathematics 2026-03-03 Huan Zhang , Xiangkai Sun , Shengjie Li , Kok Lay Teo

Closed-loop sleep modulation is an emerging research paradigm to treat sleep disorders and enhance sleep benefits. However, two major barriers hinder the widespread application of this research paradigm. First, subjects often need to be…

Signal Processing · Electrical Eng. & Systems 2022-11-24 Mingzhe Sun , Aaron Zhou , Naize Yang , Yaqian Xu , Yuhan Hou , Xilin Liu

Brain state regulates sensory processing and motor control for adaptive behavior. Internal mechanisms of brain state control are well studied, but the role of external modulation from the environment is not well understood. Here, we…

Neurons and Cognition · Quantitative Biology 2016-03-01 Christopher L. Buckley , Satohiro Tajima , Toru Yanagawa , Kana Takakura , Yasuo Nagasaka , Naotaka Fujii , Taro Toyoizumi

In this article, a biophysically realistic model of a soft octopus arm with internal musculature is presented. The modeling is motivated by experimental observations of sensorimotor control where an arm localizes and reaches a target. Major…

Systems and Control · Electrical Eng. & Systems 2025-09-11 Tixian Wang , Udit Halder , Ekaterina Gribkova , Rhanor Gillette , Mattia Gazzola , Prashant G. Mehta

Robots for physical Human-Robot Collaboration (pHRC) systems need to change their behavior and how they operate in consideration of several factors, such as the performance and intention of a human co-worker and the capabilities of…

Robotics · Computer Science 2023-10-03 Avinash Singh , Dikai Liu , Chin-Teng Lin

We present in this letter a scheme for optical interferometry. We utilize coherent-beam-stimulated two-mode squeezed light, which interacts with a phase shifter and is then squeezed again before detection. Our theoretical device has the…

Quantum Physics · Physics 2015-06-16 William N. Plick , Jonathan P. Dowling , G. S. Agarwal

People deploy top-down, goal-directed attention to accomplish tasks, such as finding lost keys. By tuning the visual system to relevant information sources, object recognition can become more efficient (a benefit) and more biased toward the…

Machine Learning · Computer Science 2020-10-02 Xiaoliang Luo , Brett D. Roads , Bradley C. Love

Robots operating in unstructured environments face significant challenges when interacting with everyday objects like doors. They particularly struggle to generalize across diverse door types and conditions. Existing vision-based and…

Robotics · Computer Science 2025-04-15 Zhi Wang , Yuchen Mo , Shengmiao Jin , Wenzhen Yuan

Electrochemiluminescence (ECL) produces light through electrochemical reactions and has shown promise for various analytic applications in biomedicine. However, the use of ECL devices (ECLDs) as light sources has been limited due to…

C. elegans shows chemotaxis using klinokinesis where the worm senses the concentration based on a single concentration sensor to compute the concentration gradient to perform foraging through gradient ascent/descent towards the target…

Neurons and Cognition · Quantitative Biology 2021-05-05 Apoorv Kishore , Vivek Saraswat , Udayan Ganguly
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